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Szabó András

Szabó András

Name: Szabó András
Affiliation: Debreceni Egyetem. Általános Orvostudományi Kar. Biokémiai és Molekuláris Biológiai Intézet / University of Debrecen. Faculty of Medicine. Department of Biochemistry and Molecular Biology
Other profiles: MTMT

Publication list

Uploaded publications:
27
Publications in DEA:
27
OA:
15
Date range:
2003-2023
2023
  1. Morales Granda, N., Toldi, V., Miczi, M., Lassoued, M., Szabó, A.: Inhibition of mouse trypsin isoforms by SPINK1 and effect of human pancreatitis-associated mutations.
    Pancreatology. 23 (4), 358-366, 2023.
    Journal metrics:
    Q1 Endocrinology (2022)
    Q1 Endocrinology, Diabetes and Metabolism (2022)
    Q1 Gastroenterology (2022)
    Q2 Hepatology (2022)
2022
2021
  1. Szabó, A., Toldi, V., Gazda, L., Demcsák, A., Tőzsér, J., Sahin-Tóth, M.: Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
    J. Biol. Chem. 296 1-13, 2021.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
  2. Toldi, V., Kassay, N., Szabó, A.: Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress.
    Pancreatology. 21 (7), 1317-1325, 2021.
    Journal metrics:
    Q2 Endocrinology
    Q1 Endocrinology, Diabetes and Metabolism
    Q1 Gastroenterology
    Q2 Hepatology
2020
  1. Toldi, V., Szabó, A., Sahin-Tóth, M.: Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation.
    J. Biol. Chem. 295 (11), 3447-3455, 2020.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2019
  1. Esteghamat, F., Broughton, J., Smith, E., Cardone, R., Tyagi, T., Guerra, M., Szabó, A., Ugwu, N., Mani, M., Azari, B., Kayingo, G., Chung, S., Fathzadeh, M., Weiss, E., Bender, J., Mane, S., Lifton, R., Adeniran, A., Nathanson, M., Gorelick, F., Hwa, J., Sahin-Tóth, M., Belfort-DeAguiar, R., Kibbey, R., Mani, A.: CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation.
    Nature Genet. 51 (8), 1233-1243, 2019.
    Journal metrics:
    D1 Genetics
  2. Lasher, D., Szabó, A., Masamune, A., Chen, J., Xiao, X., Whitcomb, D., Barmada, M., Ewers, M., Ruffert, C., Paliwal, S., Issarapu, P., Bhaskar, S., Mani, K., Chandak, G., Laumen, H., Masson, E., Kume, K., Hamada, S., Nakano, E., Seltsam, K., Bugert, P., Müller, T., Groneberg, D., Shimosegawa, T., Rosendahl, J., Férec, C., Lowe, M., Witt, H., Sahin-Tóth, M.: Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
    Am. J. Gastroenterol. 114 (6), 974-983, 2019.
    Journal metrics:
    D1 Gastroenterology
    Q1 Hepatology
2017
  1. Tóth, A., Szabó, A., Hegyi, E., Hegyi, P., Sahin-Tóth, M.: Detection of human elastase isoforms by the ScheBo pancreatic elastase 1 test.
    Am. J. Physiol.-Gastroint. Liver Physiol. 312 (6), G606-G614, 2017.
    Journal metrics:
    Q1 Gastroenterology
    Q1 Hepatology
    Q1 Physiology
    Q1 Physiology (medical)
  2. Boros, E., Szabó, A., Zboray, K., Héja, D., Pál, G., Sahin-Tóth, M.: Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes.
    J. Biol. Chem. 292 (7), 2690-2702, 2017.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2016
  1. Szabó, A., Pilsak, C., Bence, M., Witt, H., Sahin-Tóth, M.: Complex formation of human proelastases with procarboxypeptidases A1 and A2.
    J. Biol. Chem. 291 (34), 17706-17716, 2016.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2015
  1. Szabó, A., Xiao, X., Haughney, M., Spector, A., Sahin-Tóth, M., Lowe, M.: A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding.
    Biochim. Biophys. Acta. Mol. Basis Dis. 1852 (7), 1372-1379, 2015.
    Journal metrics:
    Q1 Molecular Biology
    D1 Molecular Medicine
  2. Szabó, A., Ludwig, M., Hegyi, E., Szépeová, R., Witt, H., Sahin-Tóth, M.: Mesotrypsin signature mutation in a chymotrypsin C (CTRC) variant associated with chronic pancreatitis.
    J. Biol. Chem. 290 (28), 17282-17292, 2015.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2014
  1. Szabó, A., Salameh, M., Ludwig, M., Radisky, E., Sahin-Tóth, M.: Tyrosine sulfation of human trypsin steers S2' subsite selectivity towards basic amino acids.
    PLoS One. 9 (7), e102063, 2014.
    Journal metrics:
    D1 Agricultural and Biological Sciences (miscellaneous)
    Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous)
    D1 Medicine (miscellaneous)
  2. Szabó, A., Radisky, E., Sahin-Tóth, M.: Zymogen activation confers thermodynamic stability on a key peptide bond and protects human cationic trypsin from degradation.
    J. Biol. Chem. 289 (8), 4753-4761, 2014.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2013
  1. Beer, S., Zhou, J., Szabó, A., Keiles, S., Chandak, G., Witt, H., Sahin-Tóth, M.: Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk.
    Gut. 62 (11), 1616-1624, 2013.
    Journal metrics:
    D1 Gastroenterology
  2. Batra, J., Szabó, A., Caulfield, T., Soares, A., Sahin-Tóth, M., Radisky, E.: Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation.
    J. Biol. Chem. 288 (14), 9848-9859, 2013.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
  3. Witt, H., Beer, S., Rosendahl, J., Chen, J., Chandak, G., Masamune, A., Bence, M., Szmola, R., Oracz, G., Macek, J., Bhatia, E., Steigenberger, S., Lasher, D., Bühler, F., Delaporte, C., Tebbing, J., Ludwig, M., Pilsak, C., Saum, K., Bugert, P., Masson, E., Paliwal, S., Bhaskar, S., Sobczynska-Tomaszewska, A., Bak, D., Balascak, I., Choudhuri, G., Reddy, D., Rao, G., Thomas, V., Kume, K., Nakano, E., Kakuta, Y., Shimosegawa, T., Durko, L., Szabó, A., Schnúr, A., Hegyi, P., Rakonczay, Z., Pfützer, R., Schneider, A., Groneberg, D., Braun, M., Schmidt, H., Witt, U., Friess, H., Algül, H., Landt, O., Schuelke, M., Krüger, R., Wiedenmann, B., Schmidt, F., Zimmer, K., Kovács, P., Stumvoll, M., Blüher, M., Müller, T., Janecke, A., Teich, N., Grützmann, R., Schulz, H., Mössner, J., Keim, V., Löhr, M., Férec, C., Sahin-Tóth, M.: Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
    Nature Genet. 45 (10), 1216-1220, 2013.
    Journal metrics:
    D1 Genetics
2012
  1. Szabó, A., Sahin-Tóth, M.: Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen.
    FEBS J. 279 (23), 4983-4292, 2012.
    Journal metrics:
    Q1 Biochemistry
    Q2 Cell Biology
    Q1 Molecular Biology
  2. Szabó, A., Sahin-Tóth, M.: Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
    J. Biol. Chem. 287 (24), 20701-20710, 2012.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2011
  1. Szabó, A., Héja, D., Szakács, D., Zboray, K., Kékesi, K., Radisky, E., Sahin-Tóth, M., Pál, G.: High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues.
    J. Biol. Chem. 286 (25), 22535-22545, 2011.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2010
  1. Szmola, R., Bence, M., Carpentieri, A., Szabó, A., Costello, C., Samuelson, J., Sahin-Tóth, M.: Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.
    J. Biol. Chem. 286 (3), 1819-1827, 2010.
    Journal metrics:
    D1 Biochemistry
    Q1 Cell Biology
    Q1 Molecular Biology
2009
  1. Szabó, A., Kotormán, M., Laczkó, I., Simon, L.: Improved stability and catalytic activity of chemically modified papain in aqueous organic solvents.
    Process Biochem. 44 (2), 199-204, 2009.
    Journal metrics:
    Q1 Applied Microbiology and Biotechnology
    Q2 Biochemistry
    Q1 Bioengineering
  2. Szabó, A., Kotormán, M., Laczkó, I., Simon, L.: Influence of carbohydrates on stability of papain in aqueous tetrahydrofuran mixture.
    J. Chem. Technol. Biotechnol. 84 (1), 133-138, 2009.
    Journal metrics:
    Q2 Biotechnology
    Q1 Chemical Engineering (miscellaneous)
    Q1 Fuel Technology
    Q2 Inorganic Chemistry
    Q2 Organic Chemistry
    Q2 Pollution
    Q2 Renewable Energy, Sustainability and the Environment
    Q1 Waste Management and Disposal
2007
  1. Simon, L., Kotormán, M., Szabó, A., Nemcsók, J., Laczkó, I.: The effects of organic solvent/water mixtures on the structure and catalytic activity of porcine pepsin.
    Process Biochem. 42 (5), 909-912, 2007.
    Journal metrics:
    Q1 Applied Microbiology and Biotechnology
    Q2 Biochemistry
    Q1 Bioengineering
2006
  1. Szabó, A., Kotormán, M., Laczkó, I., Simon, L.: Spectroscopic studies of stability of papain in aqueous organic solvents.
    J. Mol. Catal. B-Enzym. 41 (1-2), 43-48, 2006.
    Journal metrics:
    Q3 Biochemistry
    Q2 Bioengineering
    Q3 Catalysis
    Q1 Process Chemistry and Technology
Show all
updated: 2024-03-17, 01:21

SCImago quartiles of
scientific journal articles

Number of scientific articles: 27
Q1/D1 17 (63%)
Q1 27 (100%)
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SCImago subject areas and categories

Biochemistry, Genetics and Molecular Biology (24)
Biochemistry (16)
Molecular Biology (14)
Cell Biology (13)
Biophysics (2)
Endocrinology (2)
Genetics (2)
Biochemistry, Genetics and Molecular Biology (miscellaneous) (1)
Biotechnology (1)
Molecular Medicine (1)
Physiology (1)
Medicine (6)
Gastroenterology (5)
Hepatology (4)
Endocrinology, Diabetes and Metabolism (2)
Medicine (miscellaneous) (1)
Physiology (medical) (1)
Chemical Engineering (4)
Bioengineering (3)
Catalysis (1)
Chemical Engineering (miscellaneous) (1)
Process Chemistry and Technology (1)
Immunology and Microbiology (2)
Applied Microbiology and Biotechnology (2)
Agricultural and Biological Sciences (1)
Agricultural and Biological Sciences (miscellaneous) (1)
Chemistry (1)
Inorganic Chemistry (1)
Organic Chemistry (1)
Energy (1)
Fuel Technology (1)
Renewable Energy, Sustainability and the Environment (1)
Environmental Science (1)
Pollution (1)
Waste Management and Disposal (1)
Multidisciplinary (1)
Multidisciplinary (1)

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Other co-authors

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Chandak, Giriraj Ratan
Groneberg, David Alexander
Belfort-DeAguiar, Renata
Caulfield, Thomas R.
Costello, Catherine E.
Delaporte, Catherine
Esteghamat, Fatemehsadat
Kékesi Katalin Adrienna
Morales Granda, Nataly C.
Nathanson, Michael H.
Schneider, Alexander
Sobczynska-Tomaszewska, Agnieszka
Steigenberger, Sandra