Juhász László

University of Debrecen Faculty of Science and Technology

Institute of Chemistry

Department of Organic Chemistry

2000-

Name: Juhász László

Affiliation:

Debreceni Egyetem. Természettudományi és Technológiai Kar. Kémiai Intézet. Szerves Kémiai Tanszék / University of Debrecen. Faculty of Science and Technology. Institute of Chemistry. Department of Organic Chemistry

Other profiles: MTMT

Degree:

PhD, Debreceni Egyetem (2001)
dr. habil, Debreceni Egyetem (2015)

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Date range:

2000-2024

2024

Homolya, L., Mathomes, R. T., Varga, L., Docsa, T., Juhász, L., Hayes, J. M., Somsák, L.: Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors.
Int. J. Mol. Sci. 25 (9), 1-21, (article identifier: 4591), 2024.

doi DEA WoS Scopus

Journal metrics:

Q2 Catalysis

Q1 Computer Science Applications

Q1 Inorganic Chemistry

Q1 Medicine (miscellaneous)

Q2 Molecular Biology

D1 Organic Chemistry

Q1 Physical and Theoretical Chemistry

D1 Spectroscopy

2023

József, J., Somsák, L., Tóth, M., Juhász, L.: [2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones.
Eur. J. Org. Chem. 26 (12), 1-10, (article identifier: 202201488), 2023.

doi DEA WoS Scopus

Journal metrics:

Q2 Organic Chemistry

Q2 Physical and Theoretical Chemistry

Juhász-Tóth, É., Malecz, Á. S., Tóth, M., Homolya, Á., Kaszás, T., Somsák, L., Juhász, L.: 2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction.
New J. Chem. 47 (42), 19376-19388, 2023.

doi DEA WoS Scopus

Journal metrics:

Q3 Catalysis

Q2 Chemistry (miscellaneous)

Q2 Materials Chemistry

Homolya, Á., Jedlóczki, I., Ábrahám, A., Somsák, L., Tóth, M., Juhász, L.: Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions.
Carbohydr. Res. 529, 1-12, (article identifier: 108825), 2023.

doi DEA WoS Scopus

Journal metrics:

Q2 Analytical Chemistry

Q3 Biochemistry

Q3 Medicine (miscellaneous)

Q2 Organic Chemistry

József, J., Somsák, L., Juhász, L.: Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók.
Magy. Kém. F. 129 (3-4), 147-154, 2023.

doi DEA

2022

Kaszás, T., Szakács, B., Juhász-Tóth, É., Cservenyák, I., Kovács, T., Juhász, L., Somsák, L., Tóth, M.: Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles.
European Journal of Organic Chemistry 2022 (42), e202201103, (article identifier: 202201103), 2022.

doi DEA WoS Scopus

Journal metrics:

Q2 Organic Chemistry

Q2 Physical and Theoretical Chemistry

Kaszás, T., Baráth, B. Á., Balázs, B., Blága, T., Juhász, L., Somsák, L., Tóth, M.: Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids.
Molecules. 27 (6), 1-31, (article identifier: 1795), 2022.

doi DEA WoS Scopus

Journal metrics:

Q2 Analytical Chemistry

Q2 Chemistry (miscellaneous)

Q2 Drug Discovery

Q2 Medicine (miscellaneous)

Q3 Molecular Medicine

Q2 Organic Chemistry

Q1 Pharmaceutical Science

Q2 Physical and Theoretical Chemistry

Homolya, L., Antal, D., Nagy, M., Juhász-Tóth, É., Tóth, M., Bényei, A., Somsák, L., Juhász, L.: Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions.
Carbohydr. Res. 519, 1-10, (article identifier: 108582), 2022.

doi DEA WoS Scopus

Journal metrics:

Q2 Analytical Chemistry

Q3 Biochemistry

Q3 Medicine (miscellaneous)

Q3 Organic Chemistry

2021

Homolya, L., Juhász, L., Somsák, L.: Halogen addition to some 1-C-substituted pyranoid glycals.
Carbohydr. Res. 504, 1-11, 2021.

doi DEA

Journal metrics:

Q3 Analytical Chemistry

Q3 Biochemistry

Q3 Medicine (miscellaneous)

Q3 Organic Chemistry

2020

10.

Nagy, L., Béke, F., Juhász, L., Kovács, T., Juhász-Tóth, É., Docsa, T., Tóth, A., Gergely, P., Somsák, L., Bai, P.: Glycogen phosphorylase inhibitor, 2,3-bis[(2E)-3-(4-hydroxyphenyl)prop-2-enamido] butanedioic acid (BF142), improves baseline insulin secretion of MIN6 insulinoma cells.
PLoS One. 15 (9), 1-15, 2020.

doi DEA WoS Scopus

Journal metrics:

D1 Multidisciplinary

11.

József, J., Debreczeni, N., Eszenyi, D., Borbás, A., Juhász, L., Somsák, L.: Synthesis and photoinitiated thiol-ene reactions of exo-mannals - a new route to C-beta-d-mannosyl derivatives.
RSC Adv. 10 (57), 34825-34836, 2020.

doi DEA WoS Scopus

Journal metrics:

Q1 Chemical Engineering (miscellaneous)

Q2 Chemistry (miscellaneous)

2019

12.

Somsák, L., Bokor, É., Juhász, L., Kun, S., Lázár, L., Juhász-Tóth, É., Tóth, M.: New syntheses towards C-glycosyl type glycomimetics.
Pure Appl. Chem. 91 (7), 1159-1175, 2019.

doi DEA WoS Scopus

Journal metrics:

Q2 Chemical Engineering (miscellaneous)

Q2 Chemistry (miscellaneous)

13.

József, J., Juhász, L., Somsák, L.: Thio-click reaction of 2-deoxy-exo-glycals towards new glycomimetics: stereoselective synthesis of C-2-deoxy-D-glycopyranosyl compounds.
New J. Chem. 43 (15), 5670-5686, 2019.

doi DEA WoS Scopus

Journal metrics:

Q3 Catalysis

Q2 Chemistry (miscellaneous)

Q1 Materials Chemistry

2018

14.

Kyriakis, E., Solovou, T. G. A., Kun, S., Czifrák, K., Szőcs, B., Juhász, L., Bokor, É., Stravodimos, G. A., Kantsadi, A. L., Chatzileontiadou, D. S. M., Skamnaki, V. T., Somsák, L., Leonidas, D. D.: Probing the [beta]-pocket of the active site of human liver glycogen phosphorylase with 3-(C-[beta]-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorganic Chem. 77, 485-493, 2018.

doi DEA WoS Scopus

Journal metrics:

Q3 Biochemistry

Q2 Drug Discovery

Q3 Molecular Biology

Q2 Organic Chemistry

2017

15.

Lázár, L., Juhász, L., Batta, G., Borbás, A., Somsák, L.: Unprecedented [beta]-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals.
New J. Chem. 41 (3), 1284-1292, 2017.

doi DEA WoS Scopus

Journal metrics:

Q2 Catalysis

Q1 Chemistry (miscellaneous)

Q1 Materials Chemistry

2015

16.

Juhász, L.: Bruckner-termi előadás: Glükopiranozil-oxadiazol- és triazolkarboxamidok mint GP-inhibitorok : szintézis, enzimkinetika és szerkezet-hatás összefüggések.
Magy. kém. lapja. 70 (9), 278-280, 2015.

DEA

17.

Begum, J., Varga, G., Docsa, T., Gergely, P., Hayes, J. M., Juhász, L., Somsák, L.: Computationally motivated synthesis and enzyme kinetic evaluation of N-([beta]-D-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors.
Med. Chem. Commun. 6 (1), 80-89, 2015.

doi DEA

Journal metrics:

Q2 Biochemistry

Q1 Pharmaceutical Science

18.

József, J., Juhász, L., Illyés, T. Z., Csávás, M., Borbás, A., Somsák, L.: Photoinitiated hydrothiolation of pyranoid exo-glycals: the d-galacto and d-xylo cases.
Carbohydr. Res. 413, 63-69, 2015.

doi DEA WoS Scopus

Journal metrics:

Q2 Analytical Chemistry

Q3 Biochemistry

Q2 Medicine (miscellaneous)

Q2 Organic Chemistry

2014

19.

Kun, S., Bokor, É., Varga, G., Szőcs, B., Páhi, A., Czifrák, K., Tóth, M., Juhász, L., Docsa, T., Gergely, P., Somsák, L.: New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4- triazoles, nanomolar inhibitors of glycogen phosphorylase.
Eur. J. Med. Chem. 76, 567-579, 2014.

doi DEA

Journal metrics:

Q1 Drug Discovery

Q1 Medicine (miscellaneous)

Q1 Organic Chemistry

Q1 Pharmacology

20.

Juhász, L., Varga, G., Sztankovics, A., Béke, F., Docsa, T., Kiss-Szikszai, A., Gergely, P., Kóňa, J., Tvaroška, I., Somsák, L.: Structure-activity relationships of glycogen phosphorylase inhibitor FR258900 and its analogues: a combined synthetic, enzyme kinetics, and computational study.
ChemPlusChem. 79 (11), 1558-1568, 2014.

doi DEA WoS Scopus

Journal metrics:

Q1 Chemistry (miscellaneous)

2013

21.

Polyák, M., Varga, G., Szilágyi, B., Juhász, L., Docsa, T., Gergely, P., Begum, J., Hayes, J. M., Somsák, L.: Synthesis, enzyme kinetics and computational evaluation of N-(β-d-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors.
Bioorg. Med. Chem. 21 (18), 5738-5747, 2013.

doi DEA

Journal metrics:

Q2 Biochemistry

Q2 Clinical Biochemistry

Q1 Drug Discovery

Q3 Molecular Biology

Q2 Molecular Medicine

Q1 Organic Chemistry

Q1 Pharmaceutical Science

22.

Varga, G., Docsa, T., Gergely, P., Juhász, L., Somsák, L.: Synthesis of tartaric acid analogues of FR258900 and their evaluation as glycogen phosphorylase inhibitors.
Bioorg. Med. Chem. Lett. 23 (6), 1789-1792, 2013.

doi DEA

Journal metrics:

Q2 Biochemistry

Q2 Clinical Biochemistry

Q2 Drug Discovery

Q3 Molecular Biology

Q3 Molecular Medicine

Q2 Organic Chemistry

Q1 Pharmaceutical Science

2011

23.

Somsák, L., Bokor, É., Czifrák, K., Juhász, L., Tóth, M.: Carbohydrate derivatives and glycomimetic compounds in established and investigational therapies of type 2 diabetes mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes / Mark B. Zimering, InTech, Rijeka, 103-126, 2011. ISBN: 9789533075907

DEA

24.

Somsák, L., Bokor, É., Czifrák, K., Juhász, L., Tóth, M.: Carbohydrate Derivatives and Glycomimetic Compounds in Established and Investigational Therapies of Type 2 Diabetes Mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes. Ed.: Marc B. Zimering, InTech Open Access Publisher, Rijeka, 103-126, 2011.

DEA

25.

Tóth, M., Czecze, L., Juhász, L., Kun, S., Kónya, B., Polyák, M., Docsa, T., Gergely, P., Somsák, L.: N- és C-glükopiranozil-heterociklusok; mint potenciális glikogén foszforiláz inhibitorok.
In: MKE 1. Nemzeti Konferencia : 2011. május 22-25., Sopron : program és előadás összefoglalók. Szerk.: Adányiné Kisbocskói Nóra, Wölfling János, Magyar Kémikusok Egyesülete, Budapest, 59, 2011. ISBN: 9789639970113

DEA