Székvölgyi Lóránt
DE >
ÁOKassociate professor 2021-
DEassociate professor 2021-
Name: Székvölgyi Lóránt
Affiliation: - Debreceni Egyetem. A DE Kutatócsoportjai. MTA-DE Lendület Genom szerkezet és Rekombináció Kutatócsoport / University of Debrecen. Research Groups.
- Debreceni Egyetem. Általános Orvostudományi Kar. Biokémiai és Molekuláris Biológiai Intézet / University of Debrecen. Faculty of Medicine. Department of Biochemistry and Molecular Biology
- Debreceni Egyetem. Gyógyszerésztudományi Kar / University of Debrecen. Faculty of Pharmacy
Degree
- Ph.D., Debreceni Egyetem (2007)
- habilitáció, Debreceni Egyetem (2019)
Profession: biophysicist
Recommended links: Labor honlap - MTA-DE Lendület Genomszerkezet és Rekomvináció Kutatócsoport honlapja
Publication list
2022
Karányi, Z.,
Mosolygó, Á.,
Feró, O.,
Horváth, A.,
Boros-Oláh, B.,
Nagy, É.,
Hetey, S.,
Holb, I.,
Szaker, H.,
Miskei, M.,
Csorba, T.,
Székvölgyi, L.:
NODULIN HOMEOBOX is required for heterochromatin homeostasis in Arabidopsis.
Nat Comms. 13 1-20, 2022.
Journal metrics:
D1 Biochemistry, Genetics and Molecular Biology (miscellaneous) (2021)
D1 Chemistry (miscellaneous) (2021)
D1 Physics and Astronomy (miscellaneous) (2021)
2021
Miskei, M.,
Horváth, A.,
Viola, L.,
Varga, L.,
Nagy, É.,
Feró, O.,
Karányi, Z.,
Roszik, J.,
Miskey, C.,
Ivics, Z.,
Székvölgyi, L.:
Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome.
Computational and Structural Biotechnology Journal. 19 4032-4041, 2021.
Journal metrics:
Q1 Biochemistry
D1 Biophysics
Q1 Biotechnology
Q1 Computer Science Applications
Q1 Genetics
Q2 Structural Biology
2020
Molnár-Fodor, K.,
Sipos, É.,
Dobos, N.,
Nagy, J.,
Steiber, Z.,
Méhes, G.,
Dull, K.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Correlation between the Expression of Angiogenic Factors and Stem Cell Markers in Human Uveal Melanoma.
Life (Basel). 10 (12), 1-15, 2020.
Journal metrics:
Q2 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q1 Ecology, Evolution, Behavior and Systematics
Q1 Paleontology
Q2 Space and Planetary Science
Molnár-Fodor, K.,
Dobos, N.,
Schally, A.,
Steiber, Z.,
Oláh, G.,
Sipos, É.,
Székvölgyi, L.,
Halmos, G.:
The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma.
Oncotarget. 11 (2), 175-187, 2020.
2019
Halász, L.,
Karányi, Z.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Sipos, É.,
Nagy, É.,
Mosolygó, Á.,
Türk-Mázló, A.,
Rajnavölgyi, É.,
Halmos, G.,
Székvölgyi, L.:
Corrigendum: RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases.
Genome Res. 29 (1), 157-157, 2019.
Boros-Oláh, B.,
Dobos, N.,
Hornyák, L.,
Szabó, Z.,
Karányi, Z.,
Halmos, G.,
Roszik, J.,
Székvölgyi, L.:
Drugging the R-loop interactome: RNA-DNA hybrid binding proteins as targets for cancer therapy.
DNA Repair. 84 1-10, 2019.
Journal metrics:
Q1 Biochemistry
Q1 Cell Biology
Q1 Molecular Biology
2018
Sipos, É.,
Dobos, N.,
Rózsa, D.,
Molnár-Fodor, K.,
Oláh, G.,
Szabó, Z.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Characterization of Luteinizing hormone-releasing hormone (LH-RH-I) receptor type I as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines.
OncoTargets Ther. 11 933-941, 2018.
Journal metrics:
Q2 Oncology
Q2 Pharmacology (medical)
Hegedűs, É.,
Kókai, E.,
Nánási, P.,
Imre, L.,
Halász, L.,
Jossé, R.,
Antunovics, Z.,
Webb, M.,
El Hage, A.,
Pommier, Y.,
Székvölgyi, L.,
Dombrádi, V.,
Szabó, G.:
Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae.
Nucleic Acids Res. 46 (20), 10649-10668, 2018.
Karányi, Z.,
Halász, L.,
Acquaviva, L.,
Jonás, D.,
Hetey, S.,
Boros-Oláh, B.,
Peng, F.,
Chen, D.,
Klein, F.,
Géli, V.,
Székvölgyi, L.:
Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation.
J. Cell Biol. 217 (10), 3398-3415, 2018.
Journal metrics:
D1 Cell Biology
D1 Medicine (miscellaneous)
Hornyák, L.,
Dobos, N.,
Koncz, G.,
Karányi, Z.,
Páll, D.,
Szabó, Z.,
Halmos, G.,
Székvölgyi, L.:
The role of indoleamine-2,3-dioxygenase (IDO) in cancer development, diagnostics, and therapy.
Front. Immunol. 9 (151), 1-8, 2018.
Journal metrics:
Q1 Immunology
Q1 Immunology and Allergy
2017
Hetey, S.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Li, Q.,
Karányi, Z.,
Szabó, Z.,
Roszik, J.,
Szalóki, N.,
Vámosi, G.,
Tóth, K.,
Székvölgyi, L.:
Biophysical characterization of histone H3.3 K27M point mutation.
Biochem. Biophys. Res. Commun. 490 (3), 868-875, 2017.
Journal metrics:
Q2 Biochemistry
Q1 Biophysics
Q3 Cell Biology
Q2 Molecular Biology
Nánási, P.,
Imre, L.,
Horváth, A.,
Halász, L.,
Szántó, A.,
Kimura, H.,
Székvölgyi, L.,
Nagy, L.,
Szabó, G.:
Breaking good: +1 nucleosome destabilizationby nicking.
FEBS J. 284 (Suppl.), 221, 2017.
Qin, Y.,
Ekmekcioglu, S.,
Forget, M.,
Székvölgyi, L.,
Hwu, P.,
Grimm, E.,
Jazaeri, A.,
Roszik, J.:
Cervical cancer neoantigen landscape and immune activity is associated with HPV master regulators.
Front. Immunol. 8 1-8, 2017.
Journal metrics:
Q1 Immunology
D1 Immunology and Allergy
Sipos, É.,
Dull, K.,
Treszl, A.,
Steiber, Z.,
Méhes, G.,
Dobos, N.,
Molnár-Fodor, K.,
Oláh, G.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma.
Oncol. Rep. 37 1927-1934, 2017.
Journal metrics:
Q3 Cancer Research
Q1 Medicine (miscellaneous)
Q2 Oncology
Roszik, J.,
Fenyőfalvi, G.,
Halász, L.,
Karányi, Z.,
Székvölgyi, L.:
In Silico Restriction Enzyme Digests To Minimize Mapping Bias In Genomic Sequencing.
Mol. Ther. Methods. Clin. Dev. 6 66-67, 2017.
Journal metrics:
Q2 Genetics
Q2 Molecular Biology
Q2 Molecular Medicine
Halász, L.,
Karányi, Z.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Sipos, É.,
Nagy, É.,
Mosolygó, Á.,
Türk-Mázló, A.,
Rajnavölgyi, É.,
Halmos, G.,
Székvölgyi, L.:
RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases.
Genome Res. 27 1063-1073, 2017.
Journal metrics:
D1 Genetics
D1 Genetics (clinical)
2016
Bársony, O.,
Szalóki, G.,
Türk, D.,
Tarapcsák, S.,
Gutay-Tóth, Z.,
Bacsó, Z.,
Holb, I.,
Székvölgyi, L.,
Szabó, G.,
Csanády, L.,
Szakács, G.,
Goda, K.:
A single active catalytic site is sufficient to promote transport in P-glycoprotein.
Sci. Rep. 6 (24810), 1-16, 2016.
2015
Székvölgyi, L.,
Ohta, K.,
Nicolas, A.:
Initiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodeling.
Cold Spring Harbor Perspect. Biol. 7 (5), 1-16, 2015.
Journal metrics:
D1 Biochemistry, Genetics and Molecular Biology (miscellaneous)
2013
Acquaviva, L.,
Székvölgyi, L.,
Dichtl, B.,
Dichtl, B.,
Saint André, C.,
Nicolas, A.,
Géli, V.:
The COMPASS subunit Spp1 links histone methylation to initiation of meiotic recombination.
Science. 339 (6116), 215-218, 2013.
Journal metrics:
D1 History and Philosophy of Science
D1 Multidisciplinary
2022
Karányi, Z.,
Mosolygó, Á.,
Feró, O.,
Horváth, A.,
Boros-Oláh, B.,
Nagy, É.,
Hetey, S.,
Holb, I.,
Szaker, H.,
Miskei, M.,
Csorba, T.,
Székvölgyi, L.:
NODULIN HOMEOBOX is required for heterochromatin homeostasis in Arabidopsis.
Nat Comms. 13 1-20, 2022.
Journal metrics:
D1 Biochemistry, Genetics and Molecular Biology (miscellaneous) (2021)
D1 Chemistry (miscellaneous) (2021)
D1 Physics and Astronomy (miscellaneous) (2021)
2021
Miskei, M.,
Horváth, A.,
Viola, L.,
Varga, L.,
Nagy, É.,
Feró, O.,
Karányi, Z.,
Roszik, J.,
Miskey, C.,
Ivics, Z.,
Székvölgyi, L.:
Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome.
Computational and Structural Biotechnology Journal. 19 4032-4041, 2021.
Journal metrics:
Q1 Biochemistry
D1 Biophysics
Q1 Biotechnology
Q1 Computer Science Applications
Q1 Genetics
Q2 Structural Biology
2020
Molnár-Fodor, K.,
Sipos, É.,
Dobos, N.,
Nagy, J.,
Steiber, Z.,
Méhes, G.,
Dull, K.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Correlation between the Expression of Angiogenic Factors and Stem Cell Markers in Human Uveal Melanoma.
Life (Basel). 10 (12), 1-15, 2020.
Journal metrics:
Q2 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q1 Ecology, Evolution, Behavior and Systematics
Q1 Paleontology
Q2 Space and Planetary Science
Molnár-Fodor, K.,
Dobos, N.,
Schally, A.,
Steiber, Z.,
Oláh, G.,
Sipos, É.,
Székvölgyi, L.,
Halmos, G.:
The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma.
Oncotarget. 11 (2), 175-187, 2020.
2019
Halász, L.,
Karányi, Z.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Sipos, É.,
Nagy, É.,
Mosolygó, Á.,
Türk-Mázló, A.,
Rajnavölgyi, É.,
Halmos, G.,
Székvölgyi, L.:
Corrigendum: RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases.
Genome Res. 29 (1), 157-157, 2019.
Boros-Oláh, B.,
Dobos, N.,
Hornyák, L.,
Szabó, Z.,
Karányi, Z.,
Halmos, G.,
Roszik, J.,
Székvölgyi, L.:
Drugging the R-loop interactome: RNA-DNA hybrid binding proteins as targets for cancer therapy.
DNA Repair. 84 1-10, 2019.
Journal metrics:
Q1 Biochemistry
Q1 Cell Biology
Q1 Molecular Biology
2018
Sipos, É.,
Dobos, N.,
Rózsa, D.,
Molnár-Fodor, K.,
Oláh, G.,
Szabó, Z.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Characterization of Luteinizing hormone-releasing hormone (LH-RH-I) receptor type I as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines.
OncoTargets Ther. 11 933-941, 2018.
Journal metrics:
Q2 Oncology
Q2 Pharmacology (medical)
Hegedűs, É.,
Kókai, E.,
Nánási, P.,
Imre, L.,
Halász, L.,
Jossé, R.,
Antunovics, Z.,
Webb, M.,
El Hage, A.,
Pommier, Y.,
Székvölgyi, L.,
Dombrádi, V.,
Szabó, G.:
Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae.
Nucleic Acids Res. 46 (20), 10649-10668, 2018.
Karányi, Z.,
Halász, L.,
Acquaviva, L.,
Jonás, D.,
Hetey, S.,
Boros-Oláh, B.,
Peng, F.,
Chen, D.,
Klein, F.,
Géli, V.,
Székvölgyi, L.:
Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation.
J. Cell Biol. 217 (10), 3398-3415, 2018.
Journal metrics:
D1 Cell Biology
D1 Medicine (miscellaneous)
Hornyák, L.,
Dobos, N.,
Koncz, G.,
Karányi, Z.,
Páll, D.,
Szabó, Z.,
Halmos, G.,
Székvölgyi, L.:
The role of indoleamine-2,3-dioxygenase (IDO) in cancer development, diagnostics, and therapy.
Front. Immunol. 9 (151), 1-8, 2018.
Journal metrics:
Q1 Immunology
Q1 Immunology and Allergy
2017
Hetey, S.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Li, Q.,
Karányi, Z.,
Szabó, Z.,
Roszik, J.,
Szalóki, N.,
Vámosi, G.,
Tóth, K.,
Székvölgyi, L.:
Biophysical characterization of histone H3.3 K27M point mutation.
Biochem. Biophys. Res. Commun. 490 (3), 868-875, 2017.
Journal metrics:
Q2 Biochemistry
Q1 Biophysics
Q3 Cell Biology
Q2 Molecular Biology
Nánási, P.,
Imre, L.,
Horváth, A.,
Halász, L.,
Szántó, A.,
Kimura, H.,
Székvölgyi, L.,
Nagy, L.,
Szabó, G.:
Breaking good: +1 nucleosome destabilizationby nicking.
FEBS J. 284 (Suppl.), 221, 2017.
Qin, Y.,
Ekmekcioglu, S.,
Forget, M.,
Székvölgyi, L.,
Hwu, P.,
Grimm, E.,
Jazaeri, A.,
Roszik, J.:
Cervical cancer neoantigen landscape and immune activity is associated with HPV master regulators.
Front. Immunol. 8 1-8, 2017.
Journal metrics:
Q1 Immunology
D1 Immunology and Allergy
Sipos, É.,
Dull, K.,
Treszl, A.,
Steiber, Z.,
Méhes, G.,
Dobos, N.,
Molnár-Fodor, K.,
Oláh, G.,
Székvölgyi, L.,
Schally, A.,
Halmos, G.:
Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma.
Oncol. Rep. 37 1927-1934, 2017.
Journal metrics:
Q3 Cancer Research
Q1 Medicine (miscellaneous)
Q2 Oncology
Roszik, J.,
Fenyőfalvi, G.,
Halász, L.,
Karányi, Z.,
Székvölgyi, L.:
In Silico Restriction Enzyme Digests To Minimize Mapping Bias In Genomic Sequencing.
Mol. Ther. Methods. Clin. Dev. 6 66-67, 2017.
Journal metrics:
Q2 Genetics
Q2 Molecular Biology
Q2 Molecular Medicine
Halász, L.,
Karányi, Z.,
Boros-Oláh, B.,
Kuik-Rózsa, T.,
Sipos, É.,
Nagy, É.,
Mosolygó, Á.,
Türk-Mázló, A.,
Rajnavölgyi, É.,
Halmos, G.,
Székvölgyi, L.:
RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases.
Genome Res. 27 1063-1073, 2017.
Journal metrics:
D1 Genetics
D1 Genetics (clinical)
2016
Bársony, O.,
Szalóki, G.,
Türk, D.,
Tarapcsák, S.,
Gutay-Tóth, Z.,
Bacsó, Z.,
Holb, I.,
Székvölgyi, L.,
Szabó, G.,
Csanády, L.,
Szakács, G.,
Goda, K.:
A single active catalytic site is sufficient to promote transport in P-glycoprotein.
Sci. Rep. 6 (24810), 1-16, 2016.
2015
Székvölgyi, L.,
Ohta, K.,
Nicolas, A.:
Initiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodeling.
Cold Spring Harbor Perspect. Biol. 7 (5), 1-16, 2015.
Journal metrics:
D1 Biochemistry, Genetics and Molecular Biology (miscellaneous)
2013
Acquaviva, L.,
Székvölgyi, L.,
Dichtl, B.,
Dichtl, B.,
Saint André, C.,
Nicolas, A.,
Géli, V.:
The COMPASS subunit Spp1 links histone methylation to initiation of meiotic recombination.
Science. 339 (6116), 215-218, 2013.
Journal metrics:
D1 History and Philosophy of Science
D1 Multidisciplinary
2010
2009
Székvölgyi, L.,
Imre, L.,
Doan-Xuan, Q.,
Hegedűs, É.,
Bacsó, Z.,
Szabó, G.:
Flow Cytometric and Laser Scanning Microscopic Approaches in Epigenetics Research.
Methods Mol. Biol. 567 99-111, 2009.
Journal metrics:
Q3 Genetics
Q3 Molecular Biology
Hegedűs, É.,
Kókai, E.,
Vereb, G.,
Bacsó, Z.,
Székvölgyi, L.,
Dombrádi, V.,
Szabó, G.:
Mapping the arrangement of nicks marking loop-size domains in yeast chromatin.
Cell. Oncol. 31 (2), 143-144, 2009.
Máthé, C.,
Beyer, D.,
Erdődi, F.,
Serfőző, Z.,
Székvölgyi, L.,
Vasas, G.,
Mikóné Hamvas, M.,
Jámbrik, K.,
Gonda, S.,
Kiss, A.,
Máthéné Szigeti, Z.,
Surányi, G.:
Microcystin-LR induces abnormal root development by altering microtubule organization in tissue-cultured common reed (Phragmites australis) plantlets.
Aquat. Toxicol. 92 (3), 122-130, 2009.
Journal metrics:
D1 Aquatic Science
D1 Health, Toxicology and Mutagenesis
2008
Hegedűs, É.,
Imre, L.,
Pataki, J.,
Lizanecz, E.,
Székvölgyi, L.,
Fazakas, F.,
Bacsó, Z.,
Tóth, A.,
Szabó, M.,
Seres, Z.,
Szabó, G.:
Heteroduplex analysis using flow cytometric microbead assays to detect deletions, insertions, and single-strand lesions.
Cytometry A. 73 (3), 238-245, 2008.
Journal metrics:
Q3 Cell Biology
Q1 Histology
Q1 Pathology and Forensic Medicine
2007
Székvölgyi, L.,
Rákosy, Z.,
Bálint, B.,
Kókai, E.,
Imre, L.,
Vereb, G.,
Bacsó, Z.,
Goda, K.,
Varga, S.,
Balázs, M.,
Dombrádi, V.,
Nagy, L.,
Szabó, G.:
Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA.
Proc. Natl. Acad. Sci. U.S.A. 104 (38), 14964-14969, 2007.
2006
Székvölgyi, L.,
Bálint, B.,
Imre, L.,
Goda, K.,
Szabó, M.,
Nagy, L.,
Szabó, G.:
Chip-on-beads: flow-cytometric evaluation of chromatin immunoprecipitation.
Cytometry A. 69A (10), 1086-1091, 2006.
Journal metrics:
Q3 Cell Biology
Q1 Histology
Q1 Pathology and Forensic Medicine
Székvölgyi, L.,
Hegedűs, É.,
Molnár, M.,
Bacsó, Z.,
Szarka, K.,
Beck, Z.,
Dombrádi, V.,
Austin, C.,
Szabó, G.:
Nick-forming sequences may be involved in the organization of eukaryotic chromatin into ~50 kbp loops.
Histochem. Cell Biol. 125 (1-2), 63-73, 2006.
Journal metrics:
Q2 Cell Biology
Q1 Histology
D1 Medical Laboratory Technology
Q2 Molecular Biology
2005
Pataki, J.,
Szabó, M.,
Lantos, E.,
Székvölgyi, L.,
Molnár, M.,
Hegedűs, É.,
Bacsó, Z.,
Kappelmayer, J.,
Lustyik, G.,
Szabó, G.:
Biological microbeads for flow-cytometric immunoassays, enzyme titrations, and quantitative PCR.
Cytometry A. 68 (1), 45-52, 2005.
Journal metrics:
Q3 Cell Biology
Q2 Histology
Q1 Pathology and Forensic Medicine
2003
Szilágyi, I.,
Varga, T.,
Székvölgyi, L.,
Hegedűs, É.,
Goda, K.,
Kaczur, V.,
Bacsó, Z.,
Nakayama, Y.,
Pósafi, J.,
Pongor, S.,
Szabó, G.:
Non-random features of loop-size chromatin fragmentation.
J. Cell. Biochem. 89 (6), 1193-1205, 2003.
Journal metrics:
Q1 Biochemistry
Q2 Cell Biology
Q2 Molecular Biology
Show all
updated: 2023-02-05, 01:53
