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Somsák László
Somsák László
DE
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TTK
Institute of Chemistry
Department of Organic Chemistry
egyetemi tanár
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Name:
Somsák László
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Profession:
chemist
Media links (6)
Glikogén foszforiláz gátlás monoszacharid-származékokkal
Cukorbetegség elleni szereket fejlesztenek Debrecenben
A máj glükóztermelését csökkentő szerek fejlesztésén dolgoznak a Debreceni Egyetem Szerves Kémiai Tanszékén
Címlapon a debreceni kutatók
Címlapon a debreceni kutatók
Új vegyület a cukorbetegek szolgálatában
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Uploaded publications:
197
Publications in DEA:
175
OA:
76
Date range:
1982-2024
2024
Homolya, L.
,
Mathomes, R.
,
Varga, L.
,
Docsa, T.
,
Juhász, L.
,
Hayes, J.
,
Somsák, L.
:
Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors
.
Int. J. Mol. Sci.
25 (9), 1-21, 2024.
Journal metrics:
Q2
Catalysis (2023)
Q1
Computer Science Applications (2023)
D1
Inorganic Chemistry (2023)
Q1
Medicine (miscellaneous) (2023)
Q2
Molecular Biology (2023)
D1
Organic Chemistry (2023)
Q1
Physical and Theoretical Chemistry (2023)
D1
Spectroscopy (2023)
2023
József, J.
,
Somsák, L.
,
Tóth, M.
,
Juhász, L.
:
[2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones
.
Eur. J. Org. Chem.
26 (12), 1-10, 2023.
Journal metrics:
Q2
Organic Chemistry
Q2
Physical and Theoretical Chemistry
Juhász-Tóth, É.
,
Malecz, Á.
,
Tóth, M.
,
Homolya, Á.
,
Kaszás, T.
,
Somsák, L.
,
Juhász, L.
:
2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction
.
New J. Chem.
47 (42), 19376-19388, 2023.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q2
Materials Chemistry
Homolya, Á.
,
Jedlóczki, I.
,
Ábrahám, A.
,
Somsák, L.
,
Tóth, M.
,
Juhász, L.
:
Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions
.
Carbohydr. Res.
529 1-12, 2023.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q2
Organic Chemistry
Kun, S.
,
Mathomes, R.
,
Docsa, T.
,
Somsák, L.
,
Hayes, J.
:
Design and Synthesis of 3-(β-D-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential
.
Molecules.
28 (7), 1-19, 2023.
Journal metrics:
Q1
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
József, J.
,
Somsák, L.
,
Juhász, L.
:
Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók
.
Magy. Kém. F.
129 (3-4), 147-154, 2023.
Bokor, É.
,
Kecskés, D.
,
Gombás, F.
,
Fehér, A.
,
Kardos, E.
,
Dabian, A.
,
Vonza, Z.
,
Szennyes, E.
,
Somsák, L.
:
First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines
.
New Journal of Chemistry
47 (1), 56-74, 2023.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q2
Materials Chemistry
Kacsir, I.
,
Sipos, A.
,
Kiss, T.
,
Major, E.
,
Bajusz, N.
,
Tóth, E.
,
Buglyó, P.
,
Somsák, L.
,
Kardos, G.
,
Bai, P.
,
Bokor, É.
:
Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria
.
Front. Chem.
11 1-18, 2023.
Journal metrics:
Q1
Chemistry (miscellaneous)
Kacsir, I.
,
Sipos, A.
,
Major, E.
,
Bajusz, N.
,
Bényei, A.
,
Buglyó, P.
,
Somsák, L.
,
Kardos, G.
,
Bai, P.
,
Bokor, É.
:
Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities
.
Molecules.
28 (7), 1-55, 2023.
Journal metrics:
Q1
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Lázár, L.
,
Tsagkarakou, A.
,
Stravodimos, G.
,
Kontopidis, G.
,
Leffler, H.
,
Nilsson, U.
,
Somsák, L.
,
Leonidas, D.
:
Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3 - Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
.
Journal of Medicinal Chemistry
66 (17), 12420-12431, 2023.
Journal metrics:
D1
Drug Discovery
D1
Molecular Medicine
2022
Kiss, M.
,
Timári, I.
,
Barna, T.
,
Mészáros, Z.
,
Slámová, K.
,
Bojarová, P.
,
Křen, V.
,
Hayes, J.
,
Somsák, L.
:
2-Acetamido-2-deoxy-d-glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes
.
Int. J. Mol. Sci.
23 (3), 1-18, 2022.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
D1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Kaszás, T.
,
Szakács, B.
,
Juhász-Tóth, É.
,
Cservenyák, I.
,
Kovács, T.
,
Juhász, L.
,
Somsák, L.
,
Tóth, M.
:
Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles
.
European Journal of Organic Chemistry
2022 (42), e202201103, 2022.
Journal metrics:
Q2
Organic Chemistry
Q2
Physical and Theoretical Chemistry
Kaszás, T.
,
Baráth, B.
,
Balázs, B.
,
Blága, T.
,
Juhász, L.
,
Somsák, L.
,
Tóth, M.
:
Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids
.
Molecules.
27 (6), 1-31, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Bokor, É.
,
Ferenczi, A.
,
Hashimov, M.
,
Juhász-Tóth, É.
,
Götz, Z.
,
Zaki, A.
,
Somsák, L.
:
First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of
.
Molecules.
27 (22), 1-16, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Kánya, N.
,
Kun, S.
,
Somsák, L.
:
Glycopyranosylidene-Spiro-Morpholinones: Evaluation of the Synthetic Possibilities Based on Glyculosonamide Derivatives and a New Method for the Construction of the Morpholine Ring
.
Molecules.
27 (22), 1-18, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Homolya, L.
,
Antal, D.
,
Nagy, M.
,
Juhász-Tóth, É.
,
Tóth, M.
,
Bényei, A.
,
Somsák, L.
,
Juhász, L.
:
Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions
.
Carbohydr. Res.
519 1-10, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q3
Organic Chemistry
Kacsir, I.
,
Sipos, A.
,
Bényei, A.
,
Janka, E.
,
Buglyó, P.
,
Somsák, L.
,
Bai, P.
,
Bokor, É.
:
Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models
.
Int. J. Mol. Sci.
23 (2), 1-39, 2022.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
D1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Balázs, B.
,
Tóth, Z.
,
Kacsir, I.
,
Sipos, A.
,
Buglyó, P.
,
Somsák, L.
,
Bokor, É.
,
Kardos, G.
,
Bai, P.
:
Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands
.
Front. Chem.
10 1-9, 2022.
Journal metrics:
Q1
Chemistry (miscellaneous)
2021
Kaszás, T.
,
Cservenyák, I.
,
Juhász-Tóth, É.
,
Kulcsár, A.
,
Granatino, P.
,
Nilsson, U.
,
Somsák, L.
,
Tóth, M.
:
Coupling of N-tosylhydrazones with tetrazoles: synthesis of 2-beta-d-glycopyranosylmethyl-5-substituted-2H-tetrazole type glycomimetics
.
Org. Biomol. Chem.
19 (3), 605-618, 2021.
Journal metrics:
Q2
Biochemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Sipos, Á.
,
Szennyes, E.
,
Hajnal, É.
,
Kun, S.
,
Szabó, E.
,
Uray, K.
,
Somsák, L.
,
Docsa, T.
,
Bokor, É.
:
Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors
.
Pharmaceuticals.
14 (4), 1-27, 2021.
Journal metrics:
Q1
Drug Discovery
Q2
Molecular Medicine
Q1
Pharmaceutical Science
Homolya, L.
,
Juhász, L.
,
Somsák, L.
:
Halogen addition to some 1-C-substituted pyranoid glycals
.
Carbohydr. Res.
504 1-11, 2021.
Journal metrics:
Q3
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q3
Organic Chemistry
Kiss, M.
,
Szabó, E.
,
Bocska, B.
,
Sinh, L.
,
Fernandes, C.
,
Timári, I.
,
Hayes, J.
,
Somsák, L.
,
Barna, T.
:
Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives
.
Eur. J. Med. Chem.
223 1-14, 2021.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Kacsir, I.
,
Sipos, A.
,
Ujlaki, G.
,
Buglyó, P.
,
Somsák, L.
,
Bai, P.
,
Bokor, É.
:
Ruthenium half-sandwich type complexes with bidentate monosaccharide ligands show antineoplastic activity in ovarian cancer cell models through reactive oxygen species production
.
Int. J. Mol. Sci.
221 1-41, 2021.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
Q1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Tsagkarakou, A.
,
Chasapi, S.
,
Koulas, S.
,
Tsialtas, I.
,
Kyriakis, E.
,
Drakou, C.
,
Kun, S.
,
Somsák, L.
,
Spyroulias, G.
,
Psarra, A.
,
Leonidas, D.
:
Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways
.
European Journal of Medicinal Chemistry Reports.
3 1-11, 2021.
2020
Goyard, D.
,
Kónya, B.
,
Czifrák, K.
,
Larini, P.
,
Demontrond, F.
,
Leroy, J.
,
Balzarin, S.
,
Tournier, M.
,
Tousch, D.
,
Petit, P.
,
Duret, C.
,
Maurel, P.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
,
Praly, J.
,
Azay-Milhau, J.
,
Vidal, S.
:
Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition
.
Org. Biomol. Chem.
18 (5), 931-940, 2020.
Journal metrics:
Q2
Biochemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
2024
Homolya, L.
,
Mathomes, R.
,
Varga, L.
,
Docsa, T.
,
Juhász, L.
,
Hayes, J.
,
Somsák, L.
:
Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors
.
Int. J. Mol. Sci.
25 (9), 1-21, 2024.
Journal metrics:
Q2
Catalysis (2023)
Q1
Computer Science Applications (2023)
D1
Inorganic Chemistry (2023)
Q1
Medicine (miscellaneous) (2023)
Q2
Molecular Biology (2023)
D1
Organic Chemistry (2023)
Q1
Physical and Theoretical Chemistry (2023)
D1
Spectroscopy (2023)
2023
József, J.
,
Somsák, L.
,
Tóth, M.
,
Juhász, L.
:
[2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones
.
Eur. J. Org. Chem.
26 (12), 1-10, 2023.
Journal metrics:
Q2
Organic Chemistry
Q2
Physical and Theoretical Chemistry
Juhász-Tóth, É.
,
Malecz, Á.
,
Tóth, M.
,
Homolya, Á.
,
Kaszás, T.
,
Somsák, L.
,
Juhász, L.
:
2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction
.
New J. Chem.
47 (42), 19376-19388, 2023.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q2
Materials Chemistry
Homolya, Á.
,
Jedlóczki, I.
,
Ábrahám, A.
,
Somsák, L.
,
Tóth, M.
,
Juhász, L.
:
Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions
.
Carbohydr. Res.
529 1-12, 2023.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q2
Organic Chemistry
Kun, S.
,
Mathomes, R.
,
Docsa, T.
,
Somsák, L.
,
Hayes, J.
:
Design and Synthesis of 3-(β-D-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential
.
Molecules.
28 (7), 1-19, 2023.
Journal metrics:
Q1
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
József, J.
,
Somsák, L.
,
Juhász, L.
:
Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók
.
Magy. Kém. F.
129 (3-4), 147-154, 2023.
Bokor, É.
,
Kecskés, D.
,
Gombás, F.
,
Fehér, A.
,
Kardos, E.
,
Dabian, A.
,
Vonza, Z.
,
Szennyes, E.
,
Somsák, L.
:
First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines
.
New Journal of Chemistry
47 (1), 56-74, 2023.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q2
Materials Chemistry
Kacsir, I.
,
Sipos, A.
,
Kiss, T.
,
Major, E.
,
Bajusz, N.
,
Tóth, E.
,
Buglyó, P.
,
Somsák, L.
,
Kardos, G.
,
Bai, P.
,
Bokor, É.
:
Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria
.
Front. Chem.
11 1-18, 2023.
Journal metrics:
Q1
Chemistry (miscellaneous)
Kacsir, I.
,
Sipos, A.
,
Major, E.
,
Bajusz, N.
,
Bényei, A.
,
Buglyó, P.
,
Somsák, L.
,
Kardos, G.
,
Bai, P.
,
Bokor, É.
:
Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities
.
Molecules.
28 (7), 1-55, 2023.
Journal metrics:
Q1
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Lázár, L.
,
Tsagkarakou, A.
,
Stravodimos, G.
,
Kontopidis, G.
,
Leffler, H.
,
Nilsson, U.
,
Somsák, L.
,
Leonidas, D.
:
Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3 - Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
.
Journal of Medicinal Chemistry
66 (17), 12420-12431, 2023.
Journal metrics:
D1
Drug Discovery
D1
Molecular Medicine
2022
Kiss, M.
,
Timári, I.
,
Barna, T.
,
Mészáros, Z.
,
Slámová, K.
,
Bojarová, P.
,
Křen, V.
,
Hayes, J.
,
Somsák, L.
:
2-Acetamido-2-deoxy-d-glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes
.
Int. J. Mol. Sci.
23 (3), 1-18, 2022.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
D1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Kaszás, T.
,
Szakács, B.
,
Juhász-Tóth, É.
,
Cservenyák, I.
,
Kovács, T.
,
Juhász, L.
,
Somsák, L.
,
Tóth, M.
:
Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles
.
European Journal of Organic Chemistry
2022 (42), e202201103, 2022.
Journal metrics:
Q2
Organic Chemistry
Q2
Physical and Theoretical Chemistry
Kaszás, T.
,
Baráth, B.
,
Balázs, B.
,
Blága, T.
,
Juhász, L.
,
Somsák, L.
,
Tóth, M.
:
Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids
.
Molecules.
27 (6), 1-31, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Bokor, É.
,
Ferenczi, A.
,
Hashimov, M.
,
Juhász-Tóth, É.
,
Götz, Z.
,
Zaki, A.
,
Somsák, L.
:
First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of
.
Molecules.
27 (22), 1-16, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Kánya, N.
,
Kun, S.
,
Somsák, L.
:
Glycopyranosylidene-Spiro-Morpholinones: Evaluation of the Synthetic Possibilities Based on Glyculosonamide Derivatives and a New Method for the Construction of the Morpholine Ring
.
Molecules.
27 (22), 1-18, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q2
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Homolya, L.
,
Antal, D.
,
Nagy, M.
,
Juhász-Tóth, É.
,
Tóth, M.
,
Bényei, A.
,
Somsák, L.
,
Juhász, L.
:
Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions
.
Carbohydr. Res.
519 1-10, 2022.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q3
Organic Chemistry
Kacsir, I.
,
Sipos, A.
,
Bényei, A.
,
Janka, E.
,
Buglyó, P.
,
Somsák, L.
,
Bai, P.
,
Bokor, É.
:
Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models
.
Int. J. Mol. Sci.
23 (2), 1-39, 2022.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
D1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Balázs, B.
,
Tóth, Z.
,
Kacsir, I.
,
Sipos, A.
,
Buglyó, P.
,
Somsák, L.
,
Bokor, É.
,
Kardos, G.
,
Bai, P.
:
Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands
.
Front. Chem.
10 1-9, 2022.
Journal metrics:
Q1
Chemistry (miscellaneous)
2021
Kaszás, T.
,
Cservenyák, I.
,
Juhász-Tóth, É.
,
Kulcsár, A.
,
Granatino, P.
,
Nilsson, U.
,
Somsák, L.
,
Tóth, M.
:
Coupling of N-tosylhydrazones with tetrazoles: synthesis of 2-beta-d-glycopyranosylmethyl-5-substituted-2H-tetrazole type glycomimetics
.
Org. Biomol. Chem.
19 (3), 605-618, 2021.
Journal metrics:
Q2
Biochemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Sipos, Á.
,
Szennyes, E.
,
Hajnal, É.
,
Kun, S.
,
Szabó, E.
,
Uray, K.
,
Somsák, L.
,
Docsa, T.
,
Bokor, É.
:
Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors
.
Pharmaceuticals.
14 (4), 1-27, 2021.
Journal metrics:
Q1
Drug Discovery
Q2
Molecular Medicine
Q1
Pharmaceutical Science
Homolya, L.
,
Juhász, L.
,
Somsák, L.
:
Halogen addition to some 1-C-substituted pyranoid glycals
.
Carbohydr. Res.
504 1-11, 2021.
Journal metrics:
Q3
Analytical Chemistry
Q3
Biochemistry
Q3
Medicine (miscellaneous)
Q3
Organic Chemistry
Kiss, M.
,
Szabó, E.
,
Bocska, B.
,
Sinh, L.
,
Fernandes, C.
,
Timári, I.
,
Hayes, J.
,
Somsák, L.
,
Barna, T.
:
Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives
.
Eur. J. Med. Chem.
223 1-14, 2021.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Kacsir, I.
,
Sipos, A.
,
Ujlaki, G.
,
Buglyó, P.
,
Somsák, L.
,
Bai, P.
,
Bokor, É.
:
Ruthenium half-sandwich type complexes with bidentate monosaccharide ligands show antineoplastic activity in ovarian cancer cell models through reactive oxygen species production
.
Int. J. Mol. Sci.
221 1-41, 2021.
Journal metrics:
Q2
Catalysis
Q1
Computer Science Applications
Q1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
D1
Spectroscopy
Tsagkarakou, A.
,
Chasapi, S.
,
Koulas, S.
,
Tsialtas, I.
,
Kyriakis, E.
,
Drakou, C.
,
Kun, S.
,
Somsák, L.
,
Spyroulias, G.
,
Psarra, A.
,
Leonidas, D.
:
Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways
.
European Journal of Medicinal Chemistry Reports.
3 1-11, 2021.
2020
Goyard, D.
,
Kónya, B.
,
Czifrák, K.
,
Larini, P.
,
Demontrond, F.
,
Leroy, J.
,
Balzarin, S.
,
Tournier, M.
,
Tousch, D.
,
Petit, P.
,
Duret, C.
,
Maurel, P.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
,
Praly, J.
,
Azay-Milhau, J.
,
Vidal, S.
:
Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition
.
Org. Biomol. Chem.
18 (5), 931-940, 2020.
Journal metrics:
Q2
Biochemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Nagy, L.
,
Béke, F.
,
Juhász, L.
,
Kovács, T.
,
Juhász-Tóth, É.
,
Docsa, T.
,
Tóth, A.
,
Gergely, P.
,
Somsák, L.
,
Bai, P.
:
Glycogen phosphorylase inhibitor, 2,3-bis[(2E)-3-(4-hydroxyphenyl)prop-2-enamido] butanedioic acid (BF142), improves baseline insulin secretion of MIN6 insulinoma cells
.
PLoS One.
15 (9), 1-15, 2020.
Journal metrics:
D1
Multidisciplinary
Kánya, N.
,
Kun, S.
,
Batta, G.
,
Somsák, L.
:
Glycosylation with ulosonates under Mitsunobu conditions: scope and limitations
.
New J. Chem.
44 (34), 14463-14476, 2020.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q1
Materials Chemistry
Rauter, A.
,
Christensen, B.
,
Somsák, L.
,
Kosma, P.
,
Adamo, R.
:
Recent Trends in Carbohydrate Chemistry Vol 1. Synthesis, Structure and Function of Carbohydrates
.
Elsevier, Amsterdam, 476 p., 2020. ISBN: 9780128174678
Csávás, M.
,
Eszenyi, D.
,
Mező, E.
,
Lázár, L.
,
Debreczeni, N.
,
Tóth, M.
,
Somsák, L.
,
Borbás, A.
:
Stereoselective Synthesis of Carbon-Sulfur-Bridged Glycomimetics by Photoinitiated Thiol-Ene Coupling Reactions
.
Int. J. Mol. Sci.
21 (2), 1-27, 2020.
Journal metrics:
Q2
Catalysis
D1
Computer Science Applications
D1
Inorganic Chemistry
Q1
Medicine (miscellaneous)
Q2
Molecular Biology
D1
Organic Chemistry
D1
Physical and Theoretical Chemistry
D1
Spectroscopy
József, J.
,
Debreczeni, N.
,
Eszenyi, D.
,
Borbás, A.
,
Juhász, L.
,
Somsák, L.
:
Synthesis and photoinitiated thiol-ene reactions of exo-mannals - a new route to C-beta-d-mannosyl derivatives
.
RSC Adv.
10 (57), 34825-34836, 2020.
Journal metrics:
Q1
Chemical Engineering (miscellaneous)
Q2
Chemistry (miscellaneous)
Szennyes, E.
,
Gyémánt, G.
,
Somsák, L.
,
Bokor, É.
:
Synthesis of New Series of 2-C-(béta-D-glucopyranosyl)-Pyrimidines and Their Evaluation as Inhibitors of Some Glycoenzymes
.
Molecules.
25 (3), 1-18, 2020.
Journal metrics:
Q2
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Kyriakis, E.
,
Karra, A.
,
Papaioannou, O.
,
Solovou, T.
,
Skamnaki, V.
,
Liggri, P.
,
Zographos, S.
,
Szennyes, E.
,
Bokor, É.
,
Kun, S.
,
Psarra, A.
,
Somsák, L.
,
Leonidas, D.
:
The architecture of hydrogen and sulfur α-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design
.
Bioorg. Med. Chem.
28 (1), 1-10, 2020.
Journal metrics:
Q3
Biochemistry
Q2
Clinical Biochemistry
Q2
Drug Discovery
Q3
Molecular Biology
Q3
Molecular Medicine
Q2
Organic Chemistry
Q2
Pharmaceutical Science
2019
Kaszás, T.
,
Tóth, M.
,
Langer, P.
,
Somsák, L.
:
C-Glycosyl styrene type compounds by Pd-catalyzed cross-coupling reactions of anhydro-aldose tosylhydrazones with benzyl bromides
.
Adv. Synth. Catal.
361 (1), 105-117, 2019.
Journal metrics:
Q1
Catalysis
D1
Organic Chemistry
Somsák, L.
:
Glikomimetikumok kutatása a Debreceni Egyetem Szerves Kémiai Tanszékén
.
Magy. Kém. Lapja.
74 (6), 185-193, 2019.
Kun, S.
,
Kánya, N.
,
Galó, N.
,
Páhi, A.
,
Mándi, A.
,
Kurtán, T.
,
Makleit, P.
,
Veres, S.
,
Sipos, Á.
,
Docsa, T.
,
Somsák, L.
:
Glucopyranosylidene-spiro-benzo[b][1,4]oxazinones and -benzo[b][1,4]thiazinones: Synthesis and Investigation of Their Effects on Glycogen Phosphorylase and Plant Growth Inhibition
.
J. Agric. Food Chem.
67 (24), 6884-6891, 2019.
Journal metrics:
Q1
Agricultural and Biological Sciences (miscellaneous)
Q1
Chemistry (miscellaneous)
Szabó, E.
,
Kyriakis, E.
,
Psarra, A.
,
Karra, A.
,
Sipos, Á.
,
Docsa, T.
,
Stravodimos, G.
,
Katsidou, E.
,
Skamnaki, V.
,
Liggri, P.
,
Zographos, S.
,
Mándi, A.
,
Király, S.
,
Kurtán, T.
,
Leonidas, D.
,
Somsák, L.
:
Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography
.
J. Med. Chem.
62 (13), 6116-6136, 2019.
Journal metrics:
D1
Drug Discovery
Q1
Molecular Medicine
Barr, D.
,
Szennyes, E.
,
Bokor, É.
,
Al-Oanzi, Z.
,
Moffatt, C.
,
Kun, S.
,
Docsa, T.
,
Sipos, Á.
,
Davies, M.
,
Mathomes, R.
,
Snape, T.
,
Agius, L.
,
Somsák, L.
,
Hayes, J.
:
Identification of C-[béta]-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: in Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies
.
ACS Chem. Biol.
14 (7), 1460-1470, 2019.
Journal metrics:
Q1
Biochemistry
D1
Medicine (miscellaneous)
Q1
Molecular Medicine
Somsák, L.
,
Bokor, É.
,
Juhász, L.
,
Kun, S.
,
Lázár, L.
,
Juhász-Tóth, É.
,
Tóth, M.
:
New syntheses towards C-glycosyl type glycomimetics
.
Pure Appl. Chem.
91 (7), 1159-1175, 2019.
Journal metrics:
Q2
Chemical Engineering (miscellaneous)
Q2
Chemistry (miscellaneous)
Szennyes, E.
,
Bokor, É.
,
Docsa, T.
,
Sipos, Á.
,
Somsák, L.
:
Synthesis of C-β-D-glucopyranosyl derivatives of some fused azoles for the inhibition of glycogen phosphorylase
.
Carbohydr. Res.
472 33-41, 2019.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
József, J.
,
Juhász, L.
,
Somsák, L.
:
Thio-click reaction of 2-deoxy-exo-glycals towards new glycomimetics: stereoselective synthesis of C-2-deoxy-D-glycopyranosyl compounds
.
New J. Chem.
43 (15), 5670-5686, 2019.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q1
Materials Chemistry
2018
Kun, S.
,
Begum, J.
,
Kyriakis, E.
,
Stamati, E.
,
Barkas, T.
,
Szennyes, E.
,
Bokor, É.
,
Szabó, E.
,
Stravodimos, G.
,
Sipos, Á.
,
Docsa, T.
,
Gergely, P.
,
Moffatt, C.
,
Patraskaki, M.
,
Kokolaki, M.
,
Gkerdi, A.
,
Skamnaki, V.
,
Leonidas, D.
,
Somsák, L.
,
Hayes, J.
:
A multidisciplinary study of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: computation, synthesis, crystallography and kinetics reveal new potent inhibitors
.
Eur. J. Med. Chem.
147 266-278, 2018.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Nagy, L.
,
Márton, J.
,
Vida, A.
,
Kis, G.
,
Bokor, É.
,
Kun, S.
,
Gönczi, M.
,
Docsa, T.
,
Tóth, A.
,
Antal, M.
,
Gergely, P.
,
Csóka, B.
,
Pacher, P.
,
Somsák, L.
,
Bai, P.
:
Glycogen phosphorylase inhibition improves beta cell function
.
Br. J. Pharmacol.
175 (2), 301-319, 2018.
Journal metrics:
D1
Pharmacology
Kaszás, T.
,
Ivanov, A.
,
Tóth, M.
,
Ehlers, P.
,
Langer, P.
,
Somsák, L.
:
Pd-catalyzed coupling reactions of anhydro-aldose tosylhydrazones with aryl bromides to produce substituted exo-glycals
.
Carbohydr. Res.
466 30-38, 2018.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Kyriakis, E.
,
Solovou, T.
,
Kun, S.
,
Czifrák, K.
,
Szőcs, B.
,
Juhász, L.
,
Bokor, É.
,
Stravodimos, G.
,
Kantsadi, A.
,
Chatzileontiadou, D.
,
Skamnaki, V.
,
Somsák, L.
,
Leonidas, D.
:
Probing the [beta]-pocket of the active site of human liver glycogen phosphorylase with 3-(C-[beta]-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors
.
Bioorganic Chem.
77 485-493, 2018.
Journal metrics:
Q3
Biochemistry
Q2
Drug Discovery
Q3
Molecular Biology
Q2
Organic Chemistry
Kun, S.
,
Bokor, É.
,
Sipos, Á.
,
Docsa, T.
,
Somsák, L.
:
Synthesis of New C- and N-beta-D-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase
.
Molecules.
23 (3), 1-17, 2018.
Journal metrics:
Q2
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Lázár, L.
,
Borbás, A.
,
Somsák, L.
:
Synthesis of thiomaltooligosaccharides by a thio-click approach
.
Carbohydr. Res.
470 8-12, 2018.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Szennyes, E.
,
Bokor, É.
,
Langer, P.
,
Gyémánt, G.
,
Docsa, T.
,
Sipos, Á.
,
Somsák, L.
:
The first general synthesis of 2-C-(beta-D-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes
.
New J. Chem.
42 (21), 17439-17446, 2018.
Journal metrics:
Q3
Catalysis
Q2
Chemistry (miscellaneous)
Q1
Materials Chemistry
2017
Kaszás, T.
,
Tóth, M.
,
Somsák, L.
:
A new synthesis of C-beta-D-glycopyranosylmethyl sulfides by metal-free coupling of anhydro-aldose tosylhydrazones with thiols
.
New J. Chem.
41 (22), 13871-13880, 2017.
Journal metrics:
Q2
Catalysis
Q1
Chemistry (miscellaneous)
Q1
Materials Chemistry
Bokor, É.
,
Kun, S.
,
Goyard, D.
,
Tóth, M.
,
Praly, J.
,
Vidal, S.
,
Somsák, L.
:
C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential
.
Chem. Rev.
117 (3), 1687-1764, 2017.
Journal metrics:
D1
Chemistry (miscellaneous)
Szabó, E.
,
Páhi, A.
,
Somsák, L.
:
C-Glycosyl 1,2,4-triazoles: Synthesis of the 3-β-d-glucopyranosyl-1,5-disubstituted and 5-β-d-glucopyranosyl-1,3-disubstituted variants
.
Tetrahedron.
73 (27-28), 3810-3822, 2017.
Journal metrics:
Q2
Biochemistry
Q2
Drug Discovery
Q2
Organic Chemistry
Kaszás, T.
,
Tóth, M.
,
Kun, S.
,
Somsák, L.
:
Coupling of anhydro-aldose tosylhydrazones with hydroxy compounds and carboxylic acids: a new route for the synthesis of C-b-D-glycopyranosylmethyl ethers and esters
.
RSC Adv.
7 10454-10462, 2017.
Journal metrics:
Q1
Chemical Engineering (miscellaneous)
Q1
Chemistry (miscellaneous)
Szabó, E.
,
Kun, S.
,
Mándi, A.
,
Kurtán, T.
,
Somsák, L.
:
Glucopyranosylidene-Spiro-Thiazolinones: Synthetic Studies and Determination of Absolute Configuration by TDDFT-ECD Calculations
.
Molecules.
22 (10), 1760-1774, 2017.
Journal metrics:
Q1
Analytical Chemistry
Q1
Chemistry (miscellaneous)
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Q2
Physical and Theoretical Chemistry
Bokor, É.
,
Kyriakis, E.
,
Solovou, T.
,
Koppány, C.
,
Kantsadi, A.
,
Szabó, E.
,
Szakács, A.
,
Stravodimos, G.
,
Docsa, T.
,
Skamnaki, V.
,
Zographos, S.
,
Gergely, P.
,
Leonidas, D.
,
Somsák, L.
:
Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study
.
J. Med. Chem.
60 (22), 9251-9262, 2017.
Journal metrics:
D1
Drug Discovery
Q1
Molecular Medicine
Szennyes, E.
,
Bokor, É.
,
Kiss-Szikszai, A.
,
Somsák, L.
,
Pascal, Y.
:
Preparation of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-D-glycero-D-gulo-heptonimidamide
.
In: Carbohydrate Chemistry: Proven Synthetic Methods / Christian Vogel, Paul Murphy, CRC Press-Taylor & Francis Group, Boca Raton, 323-332, 2017, (Volume 4 ) ISBN: 9781498726917
Agócs, A.
,
Bokor, É.
,
Takátsy, A.
,
Lóránd, T.
,
Deli, J.
,
Somsák, L.
,
Nagy, V.
:
Synthesis of carotenoid-monosaccharide conjugates via azide-alkyne click-reaction
.
Tetrahedron.
73 (5), 519-526, 2017.
Journal metrics:
Q2
Biochemistry
Q2
Drug Discovery
Q2
Organic Chemistry
Lázár, L.
,
Juhász, L.
,
Batta, G.
,
Borbás, A.
,
Somsák, L.
:
Unprecedented [beta]-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals
.
New J. Chem.
41 (3), 1284-1292, 2017.
Journal metrics:
Q2
Catalysis
Q1
Chemistry (miscellaneous)
Q1
Materials Chemistry
Kantsadi, A.
,
Stravodimos, G.
,
Kyriakis, E.
,
Chatzileontiadou, D.
,
Solovou, T.
,
Kun, S.
,
Bokor, É.
,
Somsák, L.
:
van der Waals interactions govern C-[beta]-D-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase
.
J. Struct. Biol.
199 (1), 57-67, 2017.
Journal metrics:
Q1
Structural Biology
2016
Bokor, É.
,
Széles, Z.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
C-Glucopyranosyl-1,2,4-triazol-5-ones: synthesis and inhibition of glycogen phosphorylase
.
Carbohydr. Res.
429 128-134, 2016.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Goyard, D.
,
Kónya, B.
,
Chajistamatiou, A.
,
Chrysina, E.
,
Leroy, J.
,
Balzarin, S.
,
Tournier, M.
,
Tousch, D.
,
Petit, P.
,
Duret, C.
,
Maurel, P.
,
Somsák, L.
,
Docsa, T.
,
Gergely, P.
,
Praly, J.
,
Azay-Milhau, J.
,
Vidal, S.
:
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition
.
Eur. J. Med. Chem.
108 444-454, 2016.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Szennyes, E.
,
Bokor, É.
,
Batta, G.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Improved preparation of 4(5)-aryl-2-(β-D-glucopyranosyl)-imidazoles, the most efficient glucose analogue inhibitors of glycogen phosphorylase
.
RSC Adv.
6 (97), 94787-94794, 2016.
Journal metrics:
Q1
Chemical Engineering (miscellaneous)
Q1
Chemistry (miscellaneous)
Petrušová, M.
,
Smrtičová, H.
,
Pribulová, B.
,
Vlčková, S.
,
Uhliariková, I.
,
Docsa, T.
,
Somsák, L.
,
Petruš, L.
:
One pot InCl3-catalyzed synthesis of 1-glycosylmethyl-1H-imidazoles
.
Tetrahedron.
72 (17), 2116-2121, 2016.
Journal metrics:
Q2
Biochemistry
Q2
Drug Discovery
Q2
Organic Chemistry
Kantsadi, A.
,
Bokor, É.
,
Kun, S.
,
Stravodimos, G.
,
Chatzileontiadou, D.
,
Leonidas, D.
,
Juhász-Tóth, É.
,
Szakács, A.
,
Batta, G.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthetic, enzyme kinetic, and protein crystallographic studies of C-[béta]-D-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase
.
Eur. J. Med. Chem.
123 737-745, 2016.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Somsák, L.
:
Szénhidrát gyógyszerek
.
Debr. szle.
24 (2), 136-144, 2016.
2015
Bokor, É.
,
Kun, S.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
4(5)-Aryl-2-C-glucopyranosyl-imidazoles as New Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase
.
ACS Med. Chem. Lett.
6 1215-1219, 2015.
Journal metrics:
Q2
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Bokor, É.
,
Szennyes, E.
,
Csupász, T.
,
Tóth, N.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
C-(2-Deoxy-D-arabino-hex-1-enopyranosyl)-oxadiazoles: synthesis of possible isomers and their evaluation as glycogen phosphorylase inhibitors
.
Carbohydr. Res.
412 71-79, 2015.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Misra, A.
,
Bokor, É.
,
Kun, S.
,
Bolyog-Nagy, E.
,
Kathó, Á.
,
Joó, F.
,
Somsák, L.
:
Chemoselective hydration of glycosyl cyanides to C-glycosyl formamides using ruthenium complexes in aqueous media
.
Tetrahedron Lett.
56 (44), 5995-5998, 2015.
Journal metrics:
Q3
Biochemistry
Q2
Drug Discovery
Q2
Organic Chemistry
Begum, J.
,
Varga, G.
,
Docsa, T.
,
Gergely, P.
,
Hayes, J.
,
Juhász, L.
,
Somsák, L.
:
Computationally motivated synthesis and enzyme kinetic evaluation of N-([beta]-D-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors
.
Med. Chem. Commun.
6 (1), 80-89, 2015.
Journal metrics:
Q2
Biochemistry
Q1
Pharmaceutical Science
Szabó, M.
,
Baranyai, Z.
,
Somsák, L.
,
Fábián, I.
:
Decomposition of N-Chloroglycine in Alkaline Aqueous Solution: Kinetics and Mechanism
.
Chem. Res. Toxicol.
28 (6), 1282-1291, 2015.
Journal metrics:
Q1
Medicine (miscellaneous)
Q1
Toxicology
Somsák, L.
:
Ezerarcú szénhidrátok
.
Magy. Kém. F.
121 (1), 3, 2015.
Docsa, T.
,
Marics, B.
,
Németh, J.
,
Hüse, C.
,
Somsák, L.
,
Gergely, P.
,
Peitl, B.
:
Insulin sensitivity is modified by a glycogen phosphorylase inhibitor: glucopyranosylidene-spiro-thiohydantoin in streptozotocin-induced diabetic rats
.
Curr. Top. Med. Chem.
15 (23), 2390-2394, 2015.
Journal metrics:
Q2
Drug Discovery
Q2
Medicine (miscellaneous)
József, J.
,
Juhász, L.
,
Illyés, T.
,
Csávás, M.
,
Borbás, A.
,
Somsák, L.
:
Photoinitiated hydrothiolation of pyranoid exo-glycals: the d-galacto and d-xylo cases
.
Carbohydr. Res.
413 63-69, 2015.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Szőcs, B.
,
Bokor, É.
,
Szabó, E.
,
Kiss-Szikszai, A.
,
Tóth, M.
,
Somsák, L.
:
Synthesis of 5-aryl-3-C-glycosyl- and unsymmetrical 3,5-diaryl-1,2,4-triazoles from alkylidene-amidrazones
.
RSC Advances.
5 (54), 43620-43629, 2015.
Journal metrics:
Q1
Chemical Engineering (miscellaneous)
Q1
Chemistry (miscellaneous)
Somsák, L.
,
Pintér, I.
:
Szénhidrátok mindenütt (Carbohydrates everywhere)
.
Magy. Kém. F.
121 (1), 27-33, 2015.
Lázár, L.
,
Csávás, M.
,
Tóth, M.
,
Somsák, L.
,
Borbás, A.
:
Thio-click approach to the synthesis of stable glycomimetics
.
Chem. Pap.
69 (6), 889-895, 2015.
Journal metrics:
Q3
Biochemistry
Q2
Chemical Engineering (miscellaneous)
Q2
Chemistry (miscellaneous)
Q2
Industrial and Manufacturing Engineering
Q2
Materials Chemistry
2014
Páhi, A.
,
Czifrák, K.
,
Kövér, K.
,
Somsák, L.
:
Anomeric Spirocycles by Solvent Incorporation: Reactions of O-Peracylated (Glyculopyranose and Glyculopyranosyl Bromide)onamide Derivatives with Ketones
.
Carbohydr. Res.
403 192-201, 2014.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Czifrák, K.
,
Páhi, A.
,
Deák, S.
,
Kiss-Szikszai, A.
,
Kövér, K.
,
Docsa, T.
,
Gergely, P.
,
Alexacou, K.
,
Papakonstantinou, M.
,
Leonidas, D.
,
Zographos, S.
,
Chrysina, E.
,
Somsák, L.
:
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation for Inhibition of Glycogen Phosphorylase by Enzyme Kinetic and Crystallographic Methods
.
Bioorg. Med. Chem.
22 (15), 4028-4041, 2014.
Journal metrics:
Q2
Biochemistry
Q2
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Kun, S.
,
Bokor, É.
,
Varga, G.
,
Szőcs, B.
,
Páhi, A.
,
Czifrák, K.
,
Tóth, M.
,
Juhász, L.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4- triazoles, nanomolar inhibitors of glycogen phosphorylase
.
Eur. J. Med. Chem.
76 567-579, 2014.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Organic Chemistry
Q1
Pharmacology
Juhász, L.
,
Varga, G.
,
Sztankovics, A.
,
Béke, F.
,
Docsa, T.
,
Kiss-Szikszai, A.
,
Gergely, P.
,
Kóňa, J.
,
Tvaroška, I.
,
Somsák, L.
:
Structure-activity relationships of glycogen phosphorylase inhibitor FR258900 and its analogues: a combined synthetic, enzyme kinetics, and computational study
.
ChemPlusChem.
79 (11), 1558-1568, 2014.
Journal metrics:
Q1
Chemistry (miscellaneous)
Somsák, L.
,
Bokor, É.
,
Czibere, B.
,
Czifrák, K.
,
Koppány, C.
,
Kulcsár, L.
,
Kun, S.
,
Szilágyi, E.
,
Tóth, M.
,
Docsa, T.
,
Gergely, P.
:
Synthesis of C-xylopyranosyl- and xylopyranosylidene-spiro-heterocycles as potential inhibitors of glycogen phosphorylase
.
Carbohydr. Res.
399 38-48, 2014.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
2013
Bokor, É.
,
Fekete, A.
,
Varga, G.
,
Szőcs, B.
,
Czifrák, K.
,
Komáromi, I.
,
Somsák, L.
:
C-(β-d-Glucopyranosyl)formamidrazones, formic acid hydrazides and their transformations into 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazoles: a synthetic and computational study
.
Tetrahedron.
69 (48), 10391-10404, 2013.
Journal metrics:
Q2
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Bokor, É.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase
.
ACS Med. Chem. Lett.
4 (7), 612-615, 2013.
Journal metrics:
Q1
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Nagy, L.
,
Docsa, T.
,
Szántó, M.
,
Brunyánszki, A.
,
Hegedűs, C.
,
Márton, J.
,
Kónya, B.
,
Virág, L.
,
Somsák, L.
,
Gergely, P.
,
Bai, P.
:
Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N'-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism
.
PLoS One.
8 (7), e69420-, 2013.
Journal metrics:
D1
Agricultural and Biological Sciences (miscellaneous)
Q1
Biochemistry, Genetics and Molecular Biology (miscellaneous)
D1
Medicine (miscellaneous)
Somsák, L.
,
Czifrák, K.
:
Radical-mediated brominations at ring-positions of carbohydrates - 35 years later
.
In: Carbohydrate Chemistry / A. P. Rauter, T. K. Lindhorst, The Royal Society of Chemistry, Cambridge, 1-37, 2013. ISBN: 9781849735872
Farkas, E.
,
Szabó, O.
,
Tircsó, G.
,
Somsák, L.
:
Relaxometric determination of binding between Mn(II)-UDP and Mn(II)-UDP-glucose in aqueous solution
.
Carbohydr. Res.
368 68-72, 2013.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Polyák, M.
,
Varga, G.
,
Szilágyi, B.
,
Juhász, L.
,
Docsa, T.
,
Gergely, P.
,
Begum, J.
,
Hayes, J.
,
Somsák, L.
:
Synthesis, enzyme kinetics and computational evaluation of N-(β-d-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors
.
Bioorg. Med. Chem.
21 (18), 5738-5747, 2013.
Journal metrics:
Q2
Biochemistry
Q2
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Szőcs, B.
,
Tóth, M.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of 2-(β-D-glucopyranosyl)-5-(substituted-amino)-1,3,4-oxa-and -thiadiazoles for the inhibition of glycogen phosphorylase
.
Carbohydr. Res.
381C 187-195, 2013.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Tóth, M.
,
Szőcs, B.
,
Kaszás, T.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of 2-(β-D-glucopyranosylamino)-5-substituted-1,3,4-oxadiazoles for inhibition of glycogen phosphorylase
.
Carbohydr. Res.
381C 196-204, 2013.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Bokor, É.
,
Szilágyi, E.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of substituted 2-(β-d-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase
.
Carbohydr. Res.
381C 179-186, 2013.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Varga, G.
,
Docsa, T.
,
Gergely, P.
,
Juhász, L.
,
Somsák, L.
:
Synthesis of tartaric acid analogues of FR258900 and their evaluation as glycogen phosphorylase inhibitors
.
Bioorg. Med. Chem. Lett.
23 (6), 1789-1792, 2013.
Journal metrics:
Q2
Biochemistry
Q2
Clinical Biochemistry
Q2
Drug Discovery
Q3
Molecular Biology
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Lázár, L.
,
Csávás, M.
,
Hadházi, Á.
,
Herczeg, M.
,
Tóth, M.
,
Somsák, L.
,
Barna, T.
,
Herczegh, P.
,
Borbás, A.
:
Systematic study on free radical hydrothiolation of unsaturated monosaccharide derivatives with exo- and endocyclic double bonds
.
Org. Biomol. Chem.
11 (32), 5339-5350, 2013.
Journal metrics:
Q1
Biochemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
2012
Bokor, É.
,
Koppány, C.
,
Gonda, Z.
,
Novák, Z.
,
Somsák, L.
:
Evaluation of bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) as catalyst for the synthesis of 1-glycopyranosyl-4-substituted-1,2,3-triazoles
.
Carbohydr. Res.
351 42-48, 2012.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Nagy, V.
,
Felföldi, N.
,
Kónya, B.
,
Praly, J.
,
Docsa, T.
,
Gergely, P.
,
Chrysina, E.
,
Tiraidis, C.
,
Kosmopoulou, M.
,
Alexacou, K.
,
Konstantakaki, M.
,
Leonidas, D.
,
Zographos, S.
,
Oikonomakos, N.
,
Kozmon, S.
,
Tvaroška, I.
,
Somsák, L.
:
N-(4-Substituted-benzoyl)-N'-(beta-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods
.
Bioorg. Med. Chem.
20 (5), 1801-1816, 2012.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q2
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
D1
Pharmaceutical Science
Tóth, M.
,
Somsák, L.
,
Goyard, D.
:
Preparation of 2,6-Anhydro-Aldose-Tosylhydrazones
.
In: Carbohydrate Chemistry: Proven Synthetic Methods Vol. 1.. Ed.: Pavol Kováč, CRC Press, Boca Raton, 355-365, 2012. ISBN: 9781439866894
Tóth, M.
,
Kun, S.
,
Somsák, L.
,
Goyard, D.
:
Preparation of exo-Glycals from 2,6-Anhydro-aldose-tosylhydrazones
.
In: Carbohydrate Chemistry : Proven Synthetic Methods Vol. 1.. Ed.: Pavol Kováč, CRC Press, Boca Raton, 367-375, 2012. ISBN: 9781439866894
Kónya, B.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of heterocyclic N-(beta-d-glucopyranosyl)carboxamides for inhibition of glycogen phosphorylase
.
Carbohydr. Res.
351 56-63, 2012.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
2011
Somsák, L.
,
Bokor, É.
,
Czifrák, K.
,
Juhász, L.
,
Tóth, M.
:
Carbohydrate Derivatives and Glycomimetic Compounds in Established and Investigational Therapies of Type 2 Diabetes Mellitus
.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes. Ed.: Marc B. Zimering, InTech Open Access Publisher, Rijeka, 103-126, 2011.
Somsák, L.
,
Bokor, É.
,
Czifrák, K.
,
Juhász, L.
,
Tóth, M.
:
Carbohydrate derivatives and glycomimetic compounds in established and investigational therapies of type 2 diabetes mellitus
.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes / Mark B. Zimering, InTech, Rijeka, 103-126, 2011. ISBN: 9789533075907
Oscarson, S.
,
Somsák, L.
:
Carbohydrates as ligands: synthetic and biological aspects
.
Carbohydr. Res.
346 (12), 1357, 2011.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Docsa, T.
,
Czifrák, K.
,
Hüse, C.
,
Somsák, L.
,
Gergely, P.
:
Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats
.
Mol. Med. Rep.
4 (3), 477-481, 2011.
Journal metrics:
Q4
Biochemistry
Q4
Cancer Research
Q4
Genetics
Q4
Molecular Biology
Q4
Molecular Medicine
Q3
Oncology
Somsák, L.
:
Glucose derived inhibitors of glycogen phosphorylase
.
C. R. Chim.
14 (2-3), 211-223, 2011.
Journal metrics:
Q1
Chemical Engineering (miscellaneous)
Q2
Chemistry (miscellaneous)
Czifrák, K.
,
Gyóllai, V.
,
Kövér, K.
,
Somsák, L.
:
Ritter-type reaction of C-(1-bromo-1-deoxy-d-glycopyranosyl)formamides and its application for the synthesis of oligopeptides incorporating anomeric [alpha]-amino acids
.
Carbohydr. Res.
346 (14), 2104-2112, 2011.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Kun, S.
,
Nagy, G.
,
Tóth, M.
,
Czecze, L.
,
Van Nhien, A.
,
Docsa, T.
,
Gergely, P.
,
Charavgi, M.
,
Skourti, P.
,
Chrysina, E.
,
Patonay, T.
,
Somsák, L.
:
Synthesis of variously coupled conjugates of d-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase
.
Carbohydr. Res.
346 (12), 1427-1438, 2011.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
2010
Tóth, M.
,
Somsák, L.
:
5'-Uridyl derivatives of N-glycosyl allophanic acid and biuret
.
Carbohydr. Res.
345 (1), 163-167, 2010.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Somsák, L.
,
Bokor, É.
,
Czifrák, K.
,
Kónya, B.
,
Kun, S.
,
Tóth, M.
:
A glikogén foszforiláz glükózanalóg gátlószerei, mint potenciális antidiabetikumok
.
Magy. Kém. F.
116 (1), 19-30, 2010.
Somsák, L.
:
Inhibition of glycogenolysis towards antidiabetic and other therapies
.
Mini rev. med. chem.
10 (12), 1091-1092, 2010.
Journal metrics:
Q2
Drug Discovery
Q1
Medicine (miscellaneous)
Q2
Pharmacology
Bokor, É.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of 1-(D-glucopyranosyl)-1,2,3-triazoles and their evaluation as glycogen phosphorylase inhibitors
.
Bioorg. Med. Chem.
18 (3), 1171-1180, 2010.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Felföldi, N.
,
Tóth, M.
,
Chrysina, E.
,
Charavgi, M.
,
Alexacou, K.
,
Somsák, L.
:
Synthesis of new glycosyl biuret and urea derivatives as potential glycoenzyme inhibitors
.
Carbohydr. Res.
345 (2), 208-213, 2010.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Cheng, K.
,
Liu, J.
,
Sun, H.
,
Bokor, É.
,
Czifrák, K.
,
Kónya, B.
,
Tóth, M.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Tethered derivatives of D-glucose and pentacyclic triterpenes for homo/heterobivalent inhibition of glycogen phosphorylase
.
New J. Chem.
34 1450-1464, 2010.
Journal metrics:
Q2
Catalysis
Q1
Chemistry (miscellaneous)
Q1
Materials Chemistry
2009
Chrysina, E.
,
Bokor, É.
,
Alexacou, K.
,
Charavgi, M.
,
Oikonomakos, G.
,
Zographos, S.
,
Leonidas, D.
,
Oikonomakos, N.
,
Somsák, L.
:
Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case
.
Tetrahedron Asymmetry.
20 (6-8), 733-740, 2009.
Journal metrics:
Q2
Catalysis
Q1
Inorganic Chemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Somsák, L.
:
A szénhidrátkód
.
Magyar Tud.
170 (7), 789-795, 2009.
Somsák, L.
,
Tóth, M.
:
Az élet megfejtésre váró titkosírása, a szénhidrátkód
.
Magy. kém. lapja.
64 (7-8), 233-239, 2009.
Nagy, V.
,
Benltifa, M.
,
Vidal, S.
,
Berzsényi, E.
,
Teilhet, C.
,
Czifrák, K.
,
Batta, G.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
,
Praly, J.
:
Glucose-based spiro-heterocycles as potent inhibitors of glycogen phosphorylase
.
Bioorg. Med. Chem.
17 (15), 5696-5707, 2009.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Farkas, E.
,
Lente, G.
,
Somsák, L.
:
Kémia-, vegyész- és kémia-tanár-képzés a háromciklusú felsőoktatásban
.
Magy. kém. lapja.
64 (10), 294-300, 2009.
Somsák, L.
:
Molekulák térben és időben: beszámoló az MTA Kémiai Osztályának Tudományos üléséről : Az élet édes szavai, avagy mit rejt a szénhidrátkód?
.
Magy. kém. lapja.
64 (1), 16, 2009.
Czakó, Z.
,
Juhász, L.
,
Kenéz, Á.
,
Czifrák, K.
,
Somsák, L.
,
Docsa, T.
,
Gergely, P.
,
Antus, S.
:
Synthesis and glycogen phosphorylase inhibitory activity of N-(beta-D-glucopyranosyl)amides possessing 1,4-benzodioxane moiety
.
Bioorg. Med. Chem.
17 (18), 6738-6741, 2009.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Tóth, M.
,
Kun, S.
,
Bokor, É.
,
Benltifa, M.
,
Tallec, G.
,
Vidal, S.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
,
Praly, J.
:
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase
.
Bioorg. Med. Chem.
17 (13), 4773-4785, 2009.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Czifrák, K.
,
Somsák, L.
:
Synthesis of anomeric sulfonamides and their behaviour under radical-mediated bromination conditions
.
Carbohydr. Res.
344 (3), 269-277, 2009.
Journal metrics:
Q2
Analytical Chemistry
Q2
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
Nagy, V.
,
Czifrák, K.
,
Bényei, A.
,
Somsák, L.
:
Synthesis of some O-, S- and N-glycosides of hept-2-ulopyranosonamides
.
Carbohydr. Res.
344 921-927, 2009.
Journal metrics:
Q2
Analytical Chemistry
Q2
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
2008
Oikonomakos, G.
,
Somsák, L.
:
Advances in glycogen phosphorylase inhibitor design
.
Curr Opin Investig Drugs.
9 (4), 379-395, 2008.
Journal metrics:
Q1
Drug Discovery
Q1
Medicine (miscellaneous)
Q1
Pharmacology
Somsák, L.
,
Hüse, C.
,
Felföldi, N.
,
Kónya, B.
,
Kútvölgyi, K.
,
Bokor, É.
,
Czifrák, K.
:
Assessment of synthetic methods for the preparation of N-beta-D-glucopyranosyl-N'-substituted ureas, -thioureas and related compounds
.
Carbohydr. Res.
343 (12), 2083-2093, 2008.
Journal metrics:
Q2
Analytical Chemistry
Q2
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
Čolović, M.
,
Vukićević, M.
,
Šegan, D.
,
Manojlović, D.
,
Sojic, N.
,
Vukićević, R.
,
Somsák, L.
:
Electrochemical Bromination of Peracetylated Glycals
.
Adv. synth. catal.
350 29-34, 2008.
Journal metrics:
Q1
Catalysis
D1
Organic Chemistry
Somsák, L.
,
Czifrák, K.
,
Tóth, M.
,
Bokor, É.
,
Chrysina, E.
,
Alexacou, K.
,
Hayes, J.
,
Tiraidis, C.
,
Lazoura, E.
,
Leonidas, D.
,
Zographos, S.
,
Oikonomakos, G.
:
New inhibitors of glycogen phosphorylase as potential antidiabetic agents
.
Curr. Med. Chem.
15 (28), 2933-2983, 2008.
Journal metrics:
Q1
Molecular Medicine
D1
Pharmacology
Somsák, L.
,
Nagy, V.
,
Vidal, S.
,
Berzsényi, E.
,
Praly, J.
,
Czifrák, K.
:
Novel design principle validated: Glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent
.
Bioorg. Med. Chem.
18 5680-5683, 2008.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q2
Molecular Biology
Q2
Molecular Medicine
Q1
Organic Chemistry
Q1
Pharmaceutical Science
Linker, T.
,
Schanzenbach, D.
,
Elamparuthi, E.
,
Sommermann, T.
,
Fudickar, W.
,
Gyóllai, V.
,
Demuth, W.
,
Schmittel, M.
,
Somsák, L.
:
Remarkable Oxidation Stability of Glycals: Excellent Substrates for Cerium(IV)-Mediated Radical Reactions
.
J. Am. Chem. Soc.
130 (47), 16003-16010, 2008.
Journal metrics:
D1
Biochemistry
D1
Catalysis
D1
Chemistry (miscellaneous)
D1
Colloid and Surface Chemistry
2007
Juhász, Z.
,
Micskei, K.
,
Gál, E.
,
Somsák, L.
:
Chromium(II)-complex mediated formation of C-glycosides from glycosyl halides under aqueous biphasic conditions
.
Tetrahedron Lett.
48 (41), 7351-7353, 2007.
Journal metrics:
Q2
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
2006
Anagnostou, E.
,
Kosmopoulou, M.
,
Chrysina, E.
,
Leonidas, D.
,
Hadjiloi, T.
,
Tiraidis, C.
,
Zographos, S.
,
Györgydeák, Z.
,
Somsák, L.
,
Docsa, T.
,
Gergely, P.
,
Kolisis, F.
,
Oikonomakos, G.
:
Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase
.
Bioorg. Med. Chem.
14 (1), 181-189, 2006.
Journal metrics:
Q2
Biochemistry
Q2
Clinical Biochemistry
Q2
Drug Discovery
Q3
Molecular Biology
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Micskei, K.
,
Juhász, Z.
,
Ratković, Z.
,
Somsák, L.
:
Reactivity of per-O-acetylated thioglycosides and glycosyl sulfones toward chromium(II) complexes in aqueous medium
.
Tetrahedron Lett.
47 (34), 6117-6120, 2006.
Journal metrics:
Q2
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Czifrák, K.
,
Hadady, Z.
,
Docsa, T.
,
Gergely, P.
,
Schmidt, J.
,
Wessjohann, L.
,
Somsák, L.
:
Synthesis of N-(beta-D-glucopyranosyl) monoamides of dicarboxylic acids as potential inhibitors of glycogen phosphorylase
.
Carbohydr. Res.
341 (8), 947-956, 2006.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q2
Medicine (miscellaneous)
Q2
Organic Chemistry
Gulácsi, K.
,
Juhász-Tóth, É.
,
Juhász, L.
,
Somsák, L.
,
Tóth, M.
:
Szerves kémiai praktikum III.
.
Debreceni Egyetem Kossuth Egyetemi Kiadó, Debrecen, 331 p., 2006. ISBN: 9789634732464
2005
Czifrák, K.
,
Szilágyi, P.
,
Somsák, L.
:
Anomeric [alpha]-azido acid (2-azido-2-deoxy-hept-2-ulopyranosonic acid) derivatives en route to peptides incorporating sugar amino acids
.
Tetrahedron: Asymmetry.
16 (1), 127-141, 2005.
Journal metrics:
Q2
Catalysis
Q1
Inorganic Chemistry
Q1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Elek, R.
,
Kiss, L.
,
Praly, J.
,
Somsák, L.
:
beta-D-Galactopyranosyl-thiohydroximates and D-galactopyranosylidene-spiro-oxathiazoles: synthesis and enzymatic evaluation against E. coli D-galactosidase
.
Carbohydr. Res.
340 (7), 1397-1402, 2005.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
Kandra, L.
,
Gálné Remenyik, J.
,
Batta, G.
,
Somsák, L.
,
Gyémánt, G.
,
Park, K.
:
Enzymatic synthesis of a new inhibitor of alpha-amylases: acarviosinyl-isomaltosyl-spiro-thiohydantoin
.
Carbohydr. Res.
340 (7), 1311-1317, 2005.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
Chrysina, E.
,
Kosmopoulou, M.
,
Tiraidis, C.
,
Kardakaris, R.
,
Bischler, N.
,
Leonidas, D.
,
Hadady, Z.
,
Somsák, L.
,
Docsa, T.
,
Gergely, P.
,
Oikonomakos, N.
:
Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site
.
Protein Sci.
14 (4), 873-888, 2005.
Journal metrics:
Q1
Biochemistry
D1
Medicine (miscellaneous)
Q1
Molecular Biology
Somsák, L.
,
Nagy, V.
,
Hadady, Z.
,
Felföldi, N.
,
Docsa, T.
,
Gergely, P.
:
Recent developments in the synthesis and evaluation of glucose analog inhibitors of glycogen phosphorylase as potential antidiabetic agents
.
In: Frontiers in Medicinal Chemistry - Online. Eds.: Allen B. Reitz, Atta-ur-Rahman, Bentham Science Publisher, Netherlands, 253-272, 2005.
Czifrák, K.
,
Kovács, L.
,
Kövér, K.
,
Somsák, L.
:
Synthesis of some derivatives of C-(1-deoxy-1-N-substituted-d-glucopyranosyl)formic acid (d-gluco-hept-2-ulopyranosonic acid) as potential inhibitors of glycogen phosphorylase
.
Carbohydr. Res.
340 (14), 2328-2334, 2005.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
2004
Hadady, Z.
,
Tóth, M.
,
Somsák, L.
:
C-(beta-D-Glucopyranosyl) heterocycles as potential glycogen phosphorylase inhibitors
.
Arkivoc.
2004 (7), 140-149, 2004.
Journal metrics:
Q4
Organic Chemistry
Somsák, L.
,
Czifrák, K.
,
Veres, E.
:
Selective removal of 2,2,2-trichloroethyl- and 2,2,2-trichloroethoxycarbonyl protecting groups with Zn?N-methylimidazole in the presence of reducible and acid-sensitive functionalities
.
Tetrahedron Lett.
45 (49), 9095-9097, 2004.
Journal metrics:
Q2
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Györgydeák, Z.
,
Hadady, Z.
,
Felföldi, N.
,
Krakomperger, A.
,
Nagy, V.
,
Tóth, M.
,
Brunyánszki, A.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Synthesis of N-(beta-D-glucopyranosyl)- and N-(2-acetamido-2-deoxy-beta-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase
.
Bioorg. Med. Chem.
12 (18), 4861-4870, 2004.
Journal metrics:
Q2
Biochemistry
Q2
Clinical Biochemistry
Q2
Drug Discovery
Q3
Molecular Biology
Q3
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
2003
Tóth, M.
,
Kövér, K.
,
Bényei, A.
,
Somsák, L.
:
C-Glycosylmethylene carbenes: synthesis of anhydro-aldose tosylhydrazones as precursors; generation and a new synthetic route to exo-glycals
.
Org. Biomol. Chem.
1 (22), 4039-4046, 2003.
Chrysina, E.
,
Oikonomakos, N.
,
Zographos, S.
,
Kosmopoulou, M.
,
Bischler, N.
,
Leonidas, D.
,
Kovács, L.
,
Docsa, T.
,
Gergely, P.
,
Somsák, L.
:
Crystallographic studies on α- and β-D-glucopyranosyl formamide analogues, inhibitors of glycogen phosphorylase
.
Biocatal. Biotransform.
21 (4-5), 233-242, 2003.
Journal metrics:
Q3
Biochemistry
Q3
Biotechnology
Q4
Catalysis
Somsák, L.
,
Nagy, V.
,
Hadady, Z.
,
Docsa, T.
,
Gergely, P.
:
Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments
.
Curr. Pharm. Des.
9 (15), 1177-1189, 2003.
Journal metrics:
Q1
Drug Discovery
Q1
Pharmacology
Gyémánt, G.
,
Kandra, L.
,
Nagy, V.
,
Somsák, L.
:
Inhibition of human salivary [alpha]-amylase by glucopyranosylidene-spiro-thiohydantoin
.
Biochem. Biophys. Res. Commun.
312 (2), 334-339, 2003.
Journal metrics:
Q1
Biochemistry
Q1
Biophysics
Q2
Cell Biology
Q2
Molecular Biology
Tóth, M.
,
Somsák, L.
:
Preparation of 2,6-anhydro-aldose acylhydrazones, -semicarbazones and -oximes from 2,6-anhydro-aldononitriles (glycosyl cyanides)
.
Carbohydr. Res.
338 (12), 1319-1325, 2003.
Journal metrics:
Q2
Analytical Chemistry
Q3
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
2002
Gyóllai, V.
,
Schanzenbach, D.
,
Somsák, L.
,
Linker, T.
:
Addition of malonyl radicals to glycals with C-1 acceptor groups: remarkable influence of the substituents on the product distribution
.
Chem. Commun.
2002 (12), 1294-1295, 2002.
Journal metrics:
Q1
Catalysis
D1
Ceramics and Composites
D1
Chemistry (miscellaneous)
D1
Electronic, Optical and Magnetic Materials
D1
Materials Chemistry
D1
Metals and Alloys
D1
Surfaces, Coatings and Films
Oikonomakos, N.
,
Kosmopoulou, M.
,
Zographos, S.
,
Leonidas, D.
,
Chrysina, E.
,
Somsák, L.
,
Nagy, V.
,
Praly, J.
,
Docsa, T.
,
Tóth, B.
,
Gergely, P.
:
Binding of N-acetyl-N'-β-D-glucopyranosyl urea and N-benzoyl-N'-β-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies
.
Eur. J. Biochem.
269 (6), 1684-1696, 2002.
Oikonomakos, N.
,
Skamnaki, V.
,
Ősz, E.
,
Szilágyi, L.
,
Somsák, L.
,
Docsa, T.
,
Tóth, B.
,
Gergely, P.
:
Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B
.
Bioorg. Med. Chem.
10 (2), 261-268, 2002.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q2
Organic Chemistry
Q1
Pharmaceutical Science
Czifrák, K.
,
Somsák, L.
:
Radical-mediated bromination of carbohydrate derivatives: searching for alternative reaction conditions without carbon tetrachloride
.
Tetrahedron Lett.
43 (49), 8849-8852, 2002.
Journal metrics:
Q1
Biochemistry
D1
Drug Discovery
Q1
Organic Chemistry
Lipták, A.
,
Pintér, I.
,
Somsák, L.
:
Szénhidrátkémiai kutatások Magyarországon
.
Magy. kém. f.
108 (11), 467-491, 2002.
Journal metrics:
Q3
Chemistry (miscellaneous)
2001
Somsák, L.
:
Carbanionic Reactivity of the Anomeric Center in Carbohydrates
.
Chem. Rev.
101 (1), 81-136, 2001.
Journal metrics:
D1
Chemistry (miscellaneous)
Docsa, T.
,
Somsák, L.
,
Tóth, B.
,
Gergely, P.
:
Effect of glucopyranosylidene-spiro-thiohydantoin on the enzymes of hepatic glycogen metabolism in rats
.
In: Protein Modules in Cellular Signalling. Ed.: by Ludwig Heilmeyer, Peter Friedrich, IOS Press, Amsterdam, 142-149, 2001. ISBN: 1586031805
Tóth, M.
,
Somsák, L.
:
exo-Glycals from glycosyl cyanides. First generation of C-glycosylmethylene carbenes from 2,5- and 2,6-anhydroaldose tosylhydrazones
.
J. Chem. Soc., Perkin Trans. 1.
9 942-943, 2001.
Journal metrics:
Q1
Chemistry (miscellaneous)
Somsák, L.
:
Kémiai utakon biológiailag aktív monoszacharid származékok felé
.
Debreceni Egyetem Természettudományi Kar Szerves Kémiai Tanszék, Debrecen, 23 p., 2001.
Tóth, M.
,
Somsák, L.
:
One-pot transformation of nitriles into aldehyde tosylhydrazones
.
Tetrahedron Lett.
42 (14), 2723-2725, 2001.
Journal metrics:
Q1
Biochemistry
D1
Drug Discovery
Q1
Organic Chemistry
Ősz, E.
,
Czifrák, K.
,
Deim, T.
,
Szilágyi, L.
,
Bényei, A.
,
Somsák, L.
:
Preparation of 3,5-bis-(beta-D-glycopyranosyl)-1,2,4-thiadiazoles from C-(beta-D-glycopyranosyl)thioformamides
.
Tetrahedron.
57 (25), 5429-5434, 2001.
Journal metrics:
Q1
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Kovács, G.
,
Micskei, K.
,
Somsák, L.
:
Preparation of acetylated pyranoid glycals from glycosyl halides by chromium(II) complexes under biphasic conditions
.
Carbohydr. Res.
336 (3), 225-228, 2001.
Journal metrics:
Q2
Analytical Chemistry
Q2
Biochemistry
Q1
Medicine (miscellaneous)
Q2
Organic Chemistry
Somsák, L.
,
Czifrák, K.
,
Deim, T.
,
Szilágyi, L.
,
Bényei, A.
:
Studies into the preparation of 1-deoxy-1-thiocyanato-D-glycopyranosyl cyanides and the anomeric effect of the thiocyanate group
.
Tetrahedron Asymmetry.
12 (5), 731-736, 2001.
Journal metrics:
Q2
Catalysis
Q1
Inorganic Chemistry
D1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Somsák, L.
,
Kovács, L.
,
Tóth, M.
,
Ősz, E.
,
Szilágyi, L.
,
Györgydeák, Z.
,
Dinya, Z.
,
Docsa, T.
,
Tóth, B.
,
Gergely, P.
:
Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-Gluco- and D-Xylopyranosylidene-spiro-(thio)hydantoins and N-(D-Glucopyranosyl) amides
.
J. Med. Chem.
44 (17), 2843-2848, 2001.
Journal metrics:
D1
Drug Discovery
Q1
Molecular Medicine
Ratković, Z.
,
Somsák, L.
,
Micskei, K.
,
Zucchi, C.
,
Pályi, G.
:
Synthesis of ferrocenylketyl radicals by chromium(II) complexes
.
J. Organomet. Chem.
637-639 813-819, 2001.
Journal metrics:
Q2
Biochemistry
Q1
Inorganic Chemistry
Q1
Materials Chemistry
Q1
Organic Chemistry
Q2
Physical and Theoretical Chemistry
2000
Somsák, L.
,
Nagy, V.
:
A new, scalable preparation of a glucopyranosylidene-spiro-thiohydantoin: one of the best inhibitors of glycogen phosphorylases
.
Tetrahedron Asymmetry.
11 (8), 1719-1727, 2000.
Journal metrics:
Q2
Catalysis
D1
Inorganic Chemistry
D1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Somsák, L.
,
Nagy, V.
:
Corrigendum to "A new, scalable preparation of a glucopyranosylidene-spiro-thiohydantoin: one of the best inhibitors of glycogen phosphorylases": [Tetrahedron: Asymmetry 11 (2000) 1719]
.
Tetrahedron-Asymmetry.
11 (10), 2247, 2000.
Somsák, L.
,
Nagy, V.
,
Docsa, T.
,
Tóth, B.
,
Gergely, P.
:
Gram-scale synthesis of a glucopyranosylidene-spiro-thiohydantoin and its effect on hepatic glycogen metabolism studied in vitro and in vivo
.
Tetrahedron Asymmetry.
11 405-408, 2000.
Journal metrics:
Q2
Catalysis
D1
Inorganic Chemistry
D1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Praly, J.
,
Stéfano, C.
,
Somsák, L.
:
Photolysis of glycopyranosyl azides C-1 substituted by cyano-, amido-, or tetrazolyl-groups
.
Tetrahedron Asymmetry.
11 (2), 533-537, 2000.
Journal metrics:
Q2
Catalysis
D1
Inorganic Chemistry
D1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Docsa, T.
,
Tar, K.
,
Tóth, B.
,
Somsák, L.
,
Gergely, P.
:
Regulation of hepatic glycogen metabolism by glycopyranosylidene-spiro-thiohydantoin
.
J. Physiol.-London.
5262000.
1999
Ősz, E.
,
Somsák, L.
,
Szilágyi, L.
,
Kovács, L.
,
Docsa, T.
,
Tóth, B.
,
Gergely, P.
:
Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin
.
Bioorg. Med. Chem. Lett.
9 (10), 1385-1390, 1999.
Journal metrics:
Q2
Biochemistry
Q1
Clinical Biochemistry
Q1
Drug Discovery
Q3
Molecular Biology
Q2
Molecular Medicine
Q2
Organic Chemistry
D1
Pharmaceutical Science
Gyóllai, V.
,
Somsák, L.
,
Szilágyi, L.
:
N-(l-cyano-D-glycosyl)amides: novel anomeric α-amino-acid derivatives
.
Tetrahedron Lett.
40 (20), 3969-3972, 1999.
Journal metrics:
Q1
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Somsák, L.
,
Kovács, L.
,
Gyóllai, V.
,
Ősz, E.
:
Novel glycosylidene-spiro-heterocycles from unprecedented solvent incorporation in Koenigs-Knorr-like reactions of C-(1-bromo-1-deoxy- gb s-D-glycopyranosyl)formamides
.
Kovács, G.
,
Tóth, K.
,
Dinya, Z.
,
Somsák, L.
,
Micskei, K.
:
Preparation of acylated pyranoid glycals in neutral aqueous medium by using chromium(II) complexes as reagents
.
Tetrahedron.
55 (16), 5253-5264, 1999.
Journal metrics:
Q1
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
Praly, J.
,
Di, S.
,
Somsák, L.
,
Hollósi, M.
,
Májer, Z.
,
Voelter, W.
:
Structure of C-1 substituted glycopyranosyl azides: new insights based on CD measurements
.
Tetrahedron-Asymmetry.
10 (5), 901-911, 1999.
Journal metrics:
Q2
Catalysis
Q1
Inorganic Chemistry
D1
Organic Chemistry
Q1
Physical and Theoretical Chemistry
Ősz, E.
,
Szilágyi, L.
,
Somsák, L.
,
Bényei, A.
:
Syntheses of novel glycosylidene-spiro-heterocycles related to hydantocidin
.
Tetrahedron.
55 (8), 2419-2430, 1999.
Journal metrics:
Q1
Biochemistry
Q1
Drug Discovery
Q1
Organic Chemistry
1998
Farkas, E.
,
Megyeri, K.
,
Somsák, L.
,
Kovács, L.
:
Interaction between Mo(VI) and siderophore models in aqueous solution
.
J. inorg. biochem.
70 (1), 41-47, 1998.
Gyóllai, V.
,
Somsák, L.
,
Györgydeák, Z.
:
Preparation of acetylated 1-fluoroglycopyranosyl cyanides
.
Tetrahedron.
54 13267-13276, 1998.
1997
Ősz, E.
,
Sós, E.
,
Somsák, L.
,
Szilágyi, L.
,
Dinya, Z.
:
A Straightforward route to hydantociden analogues with pyranose ring structure
.
Tetrahedron
53 (16), 5813-5824, 1997.
Somsák, L.
:
Glikomimetikumok és prekurzoraik szintézise
.
Kossuth Lajos Tudományegyetem, Debrecen, 18 p., 1997.
Berényi, S.
,
Kovács, L.
,
Patonay, T.
,
Somsák, L.
:
Szerves kémiai praktikum I.
.
Kossuth Egyetemi Kiadó, Debrecen, 222 p., 1997.
Kovács, J.
,
Pintér, I.
,
Kajtár-Peredy, M.
,
Somsák, L.
:
Unexpected reactions of (LR)2,3,4,6-tera-O-acetyl-1-azido-D-galactopyranosyl cyanide and the derived carboxamide with triphenylphosphine
.
Somsák, L.
,
Madaj, J.
,
Wisniewski, A.
:
Zinc-N-base mediated synthesis of pyranoid glycals mechanistic studies
.
1996
Kiss, L.
,
Somsák, L.
:
Evaluation of C-( gb s-D-galactosyl) and C-(2-deoxy-D-lyxo-hex-1-enopyranosil) (D-galactal type) derivatives as inhibitors of gb s-D-galactosidase from Escherichia coli
.
Kovács, G.
,
Gyarmati, J.
,
Somsák, L.
,
Micskei, K.
:
Long-lived glycosyl-chromium(III) complex intermediates in aqueous medium. Preparation of pyranoid glycals
.
Tetrahedron Lett.
37 (8), 1293-1296, 1996.
Somsák, L.
:
Preparation of amidine derivatives from 1-cyano-galactal
.
Somsák, L.
,
Sós, E.
,
Györgydeák, Z.
,
Praly, J.
,
Descotes, G.
:
Synthesis and some transformations of 1-azido-glycopyranosyl cyanides-precursors of anomeric [alpha]-amino acids
.
Tetrahedron.
52 (27), 9121-9136, 1996.
1995
Praly, J.
,
Di, S.
,
Descotes, G.
,
Faure, R.
,
Somsák, L.
,
Eperjesi, I.
:
Preparation and photolysis of 1-cyano-glycopyranosyl azides
.
1994
Mahmoud, S.
,
Somsák, L.
,
Farkas, I.
:
C-nucleosides VII. Preparation of C-(2-deoxyhex/pent-1-enopyranosyl)heterocycles
.
1993
Somsák, L.
,
Németh, I.
:
A simple method for the synthesis of acylated pyranoid glycals under aprotic conditions
.
1992
Praly, J.
,
Somsák, L.
,
Mahmoud, S.
,
Kharraf, Z.
,
Descotes, G.
,
Farkas, I.
:
Radical-mediated halogenations of anomerically N-substituted glucopyranosyl derivatives
.
J. Carbohydr. Chem.
11 (3), 201-216, 1992.
Somsák, L.
,
Praly, J.
,
Descotes, G.
:
Sodium salt of D-glucono-1,5-lactone tosylhydrazone: a ready acess to a new glucosylidene carbene precursor
.
Praly, J.
,
Stéfano, C.
,
Somsák, L.
,
Descotes, G.
:
Sugar bromoimino lactones: New sugar derivatives readily prepared from ò-D-glycosyl azides
.
J. Chem. Soc., Chem. Commun.
200-201, 1992.
1990
Somsák, L.
,
Bajza, I.
,
Batta, G.
:
Preparation of 2,6-anhydro-3-deoxyhept-(or hex-)2-enononitriles (1-cyanoglycals) from 1-bromo-D-glycosyl cyanides with zinc under aprotic conditions
.
Liebigs Ann. Chem.
12 1265-1268, 1990.
1989
Somsák, L.
:
Acetylated 1-Cyano- and 1-Cyano-2-hydroxy Derivatives of D-Galactol and D-Arabinol
.
Somsák, L.
:
A kapto-oletiv gyökstabilizáció
.
Magy. Kém. Lapja.
44 22-26, 1989.
Farkas, I.
,
Snatzke, G.
,
Somsák, L.
:
Circular Dichroism, XC: CD of 1-Cyano Derivatives of Pyranoses
.
Liebigs Ann Chem.
1989 (6), 599-600, 1989.
1986
Somsák, L.
,
Batta, G.
,
Farkas, I.
:
Preparation of 1,2-cis-glycosyl cyanides by the stereoselective reduction of acetylated l-bromo-D-glycosyl cyanides
.
Tetrahedron Lett.
48 5877-5880, 1986.
Somsák, L.
,
Batta, G.
,
Farkas, I.
,
Párkányi, L.
,
Kálmán, A.
,
Somogyi, Á.
:
Synthesis and Stereochemistry of a New Spiro Glycosylidene Heterocycle from the Reaction of 1-Bromoglycosyl Cyanides with S-Nucleophiles: Complete Identification of Hydrogen Bridges by N.M.R. Methods and X-ray Analysis
.
J. Chem. Res. Synop.
12 436-437, 1986.
Jászberényi, J.
,
Tőkés, A.
,
Mádi, I.
,
Somsák, L.
:
Szerves kémiai praktikum I-II.: oktatási segédanyag
.
KLTE, Debrecen, 1986.
1984
Somsák, L.
,
Batta, G.
,
Farkas, I.
:
Preparation of acetylated 2-heptulo- and 2-hexulo-pyranosononitriles from acetylated 1-bromo-D-glycosyl cyanides
.
Carbohydr. Res.
132 (2), 342-344, 1984.
1983
Somsák, L.
,
Batta, G.
,
Farkas, I.
:
Preparation of acetylated C-(1-bromo-d-glycosyl) heterocycles and 1-bromo-d-glycosyl cyanides
.
Carbohydr. Res.
124 (1), 43-51, 1983.
1982
Somsák, L.
,
Batta, G.
,
Farkas, I.
:
Bromination of acetylated 2,5-anhydro-aldononitriles at the anomeric centre using N-bromosuccinimide: synthesis of 2,3,4,6-tetra-O-acetyl-1-bromo-d-galactopyranosyl cyanide and its d-xylopyranosyl analogue
.
Carbohydr. Res.
106 (1), C4-C5, 1982.
Farkas-Szabó, I.
,
Batta, G.
,
Somsák, L.
,
Farkas, I.
:
C-Nucleosides IV.: Preparation of 2-(polyhydroxyalkyl)-5-chloro- and 2-beta-D-glycosyl-5-chlorobenzothiazole derivatives
.
Acta chim. Acad. Sci. Hung.
109 (3), 229-236, 1982.
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Duret, Cédric
(co-authored publications: 2)
Juhász Zsuzsa
(co-authored publications: 2)
Kandra Lili
(co-authored publications: 2)
Karra, Aikaterini G.
(co-authored publications: 2)
Kiss László
(co-authored publications: 2)
Kovács Gyöngyvér
(co-authored publications: 2)
Kovács Lajos
(co-authored publications: 2)
Leroy, Jérémy
(co-authored publications: 2)
Liggri, Panagiota G. V.
(co-authored publications: 2)
Linker, Torsten
(co-authored publications: 2)
Márton Judit
(co-authored publications: 2)
Maurel, Patrick
(co-authored publications: 2)
Moffatt, Colin
(co-authored publications: 2)
Nilsson Ulf J.
(co-authored publications: 2)
Petit, Pierre
(co-authored publications: 2)
Ratković, Zoran R.
(co-authored publications: 2)
Schanzenbach, Dirk
(co-authored publications: 2)
Sós Erzsébet
(co-authored publications: 2)
Stéfano, Carméla Di
(co-authored publications: 2)
Szakács Andrea
(co-authored publications: 2)
Szilágyi Enikő
(co-authored publications: 2)
Tournier, Michel
(co-authored publications: 2)
Tousch, Didier
(co-authored publications: 2)
Tsagkarakou, Anastasia S.
(co-authored publications: 2)
Tvaroška, Igor
(co-authored publications: 2)
Adamo, Roberto
(co-authored publications: 1)
Agius, Loranne
(co-authored publications: 1)
Agócs Attila
(co-authored publications: 1)
Al-Oanzi, Ziad H.
(co-authored publications: 1)
Anagnostou, Eleni
(co-authored publications: 1)
Antal Dávid
(co-authored publications: 1)
Bajza István
(co-authored publications: 1)
Balázs Bernadett
(co-authored publications: 1)
Baráth Balázs Áron
(co-authored publications: 1)
Barkas, Thomas A.
(co-authored publications: 1)
Barr, Daniel
(co-authored publications: 1)
Berényi Sándor
(co-authored publications: 1)
Blága Tekla
(co-authored publications: 1)
Bocska Boglárka
(co-authored publications: 1)
Bojarová, Pavla
(co-authored publications: 1)
Chajistamatiou, Aikaterini S.
(co-authored publications: 1)
Chasapi, Styliani A.
(co-authored publications: 1)
Cheng, Keguang
(co-authored publications: 1)
Christensen, Björn E.
(co-authored publications: 1)
Čolović, Marija
(co-authored publications: 1)
Czecze Laura
(co-authored publications: 1)
Czibere Beáta
(co-authored publications: 1)
Csóka Balázs
(co-authored publications: 1)
Dabian Akram
(co-authored publications: 1)
Davies, Matthew P.
(co-authored publications: 1)
Deák Szabina
(co-authored publications: 1)
Deli József
(co-authored publications: 1)
Demontrond, Fanny
(co-authored publications: 1)
Demuth, Wolfgang
(co-authored publications: 1)
Drakou, Christina E.
(co-authored publications: 1)
Ehlers, Peter
(co-authored publications: 1)
Elamparuthi, Elangovan
(co-authored publications: 1)
Elek Rita
(co-authored publications: 1)
Eperjesi István
(co-authored publications: 1)
Farkas-Szabó Ilona
(co-authored publications: 1)
Faure, René
(co-authored publications: 1)
Fehér Alexandra
(co-authored publications: 1)
Ferenczi Attila
(co-authored publications: 1)
Fernandes, Conceicao Piedade
(co-authored publications: 1)
Fudickar, Werner
(co-authored publications: 1)
Gál Emese
(co-authored publications: 1)
Galó Norbert
(co-authored publications: 1)
Gkerdi, Alkistis
(co-authored publications: 1)
Gombás Ferenc
(co-authored publications: 1)
Gonda Zsombor
(co-authored publications: 1)
Götz Zsófia
(co-authored publications: 1)
Granatino, Paola
(co-authored publications: 1)
Gyarmati Julianna
(co-authored publications: 1)
Hadházi Ádám
(co-authored publications: 1)
Hadjiloi, Theodoros
(co-authored publications: 1)
Hajnal Éva
(co-authored publications: 1)
Hollósi Miklós
(co-authored publications: 1)
Ivanov, Anton
(co-authored publications: 1)
Jászberényi J. Csaba
(co-authored publications: 1)
Jedlóczki Ivett
(co-authored publications: 1)
Kajtár-Peredy Mária
(co-authored publications: 1)
Kálmán Alajos
(co-authored publications: 1)
Kardakaris, Rozina
(co-authored publications: 1)
Kardos Eszter
(co-authored publications: 1)
Kathó Ágnes
(co-authored publications: 1)
Katsidou, Elisabeth
(co-authored publications: 1)
Kecskés Dóra
(co-authored publications: 1)
Kharraf, Z. El.
(co-authored publications: 1)
Kis Gréta
(co-authored publications: 1)
Kokolaki, Maria C.
(co-authored publications: 1)
Kolisis, Fragiskos N.
(co-authored publications: 1)
Kóňa, Juraj
(co-authored publications: 1)
Konstantakaki, Maria
(co-authored publications: 1)
Kontopidis, George
(co-authored publications: 1)
Kosma, Paul
(co-authored publications: 1)
Koulas, Symeon M.
(co-authored publications: 1)
Kovács G.
(co-authored publications: 1)
Kovács József
(co-authored publications: 1)
Kovács L.
(co-authored publications: 1)
Kovács Tamara
(co-authored publications: 1)
Kozmon, Stanislav
(co-authored publications: 1)
Krakomperger Attila
(co-authored publications: 1)
Křen, Vladimír
(co-authored publications: 1)
Kulcsár Andrea
(co-authored publications: 1)
Larini, Paolo
(co-authored publications: 1)
Lazoura, E.
(co-authored publications: 1)
Leffler, Hakon
(co-authored publications: 1)
Liu, Jun
(co-authored publications: 1)
Lóránd Tamás
(co-authored publications: 1)
Madaj, Jadusz
(co-authored publications: 1)
Mádi Istvánné
(co-authored publications: 1)
Mahmoud, S. H.
(co-authored publications: 1)
Mahmoud, Saad H.
(co-authored publications: 1)
Májer Zsuzsa
(co-authored publications: 1)
Malecz Ádám Szilárd
(co-authored publications: 1)
Manojlović, Dragan
(co-authored publications: 1)
Megyeri Katalin
(co-authored publications: 1)
Mészáros, Zuzana
(co-authored publications: 1)
Misra, Anup Kumar
(co-authored publications: 1)
Nagy Gergő Zoltán
(co-authored publications: 1)
Nagy Máté
(co-authored publications: 1)
Németh Ildikó
(co-authored publications: 1)
Novák Zoltán
(co-authored publications: 1)
Oscarson, Stefan
(co-authored publications: 1)
Pacher Pál
(co-authored publications: 1)
Pályi Gyula
(co-authored publications: 1)
Papaioannou, Olga
(co-authored publications: 1)
Papakonstantinou, Maria
(co-authored publications: 1)
Park, Kwan Hwa
(co-authored publications: 1)
Párkányi László
(co-authored publications: 1)
Pascal, Yoann
(co-authored publications: 1)
Patraskaki, Myrto S.
(co-authored publications: 1)
Petruš, Ladislav
(co-authored publications: 1)
Petrušová, Mária
(co-authored publications: 1)
Polyák Mária
(co-authored publications: 1)
Pribulová, Božena
(co-authored publications: 1)
Rauter, Amália Pilar
(co-authored publications: 1)
Schmidt, Jürgen
(co-authored publications: 1)
Schmittel, Michael
(co-authored publications: 1)
Šegan, Dejan
(co-authored publications: 1)
Sinh, Luu Thanh
(co-authored publications: 1)
Skamnaki, Vicky T.
(co-authored publications: 1)
Skourti, Paraskevi V.
(co-authored publications: 1)
Slámová, Kristýna
(co-authored publications: 1)
Smrtičová, Hana
(co-authored publications: 1)
Snape, Timothy J.
(co-authored publications: 1)
Snatzke, Günther
(co-authored publications: 1)
Sojic, Neso
(co-authored publications: 1)
Sommermann, Thomas
(co-authored publications: 1)
Spyroulias, Georgios A.
(co-authored publications: 1)
Stamati, Evgenia C. V.
(co-authored publications: 1)
Sun, Hongbin
(co-authored publications: 1)
Szabó Orsolya
(co-authored publications: 1)
Széles Zsolt
(co-authored publications: 1)
Szilágyi Bence
(co-authored publications: 1)
Szilágyi Péter
(co-authored publications: 1)
Sztankovics Andrea
(co-authored publications: 1)
Takátsy Anikó
(co-authored publications: 1)
Tallec, Gaylord
(co-authored publications: 1)
Teilhet, Cathie
(co-authored publications: 1)
Tiraidis, Costas
(co-authored publications: 1)
Tóth Attila
(co-authored publications: 1)
Tóth Béla
(co-authored publications: 1)
Tóth Krisztina
(co-authored publications: 1)
Tóth Nóra
(co-authored publications: 1)
Tőkés Adrienne, Liptákné
(co-authored publications: 1)
Tsialtas, Ioannis
(co-authored publications: 1)
Uhliariková, Iveta
(co-authored publications: 1)
Uray Karen
(co-authored publications: 1)
Van Nhien, Albert Nguyen
(co-authored publications: 1)
Varga Luca
(co-authored publications: 1)
Veres Edit
(co-authored publications: 1)
Vlčková, Silvia
(co-authored publications: 1)
Voelter, Wolfgang
(co-authored publications: 1)
Vonza Zsófia
(co-authored publications: 1)
Vukićević, Mirjana
(co-authored publications: 1)
Vukićević, Rastko D.
(co-authored publications: 1)
Wessjohann, Ludger A.
(co-authored publications: 1)
Wisniewski, Andrzej
(co-authored publications: 1)
Zaki, Alshimaa Ibrahim
(co-authored publications: 1)
Zucchi, Claudia
(co-authored publications: 1)
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