Tudóstér: Herczeg Mihály publikációi

Herczeg, M., Demeter, F., Nagy, T., Rusznyák, Á., Hodek, J., Sipos, É., Lekli, I., Fenyvesi, F., Weber, J., Kéki, S., Borbás, A.: Block Synthesis and Step-Growth Polymerization of C-6-Sulfonatomethyl-Containing Sulfated Malto-Oligosaccharides and Their Biological Profiling.
Int. J. Mol. Sci. 25 (1), 1-29, 2024.

Tóth, I., Bazeli, B., Janssens, A., Lisztes, E., Racskó, M., Kelemen, B., Herczeg, M., Nagy, T., Kövér, K., Mitra, A., Borics, A., Bíró, T., Voets, T.: Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants.
eLife. "Accepted by Publisher"2024.

Lőrincz, E., Herczeg, M., Houser, J., Rievajová, M., Kuki, Á., Malinovská, L., Naesens, L., Wimmerová, M., Borbás, A., Herczegh, P., Bereczki, I.: Amphiphilic Sialic Acid Derivatives as Potential Dual-Specific Inhibitors of Influenza Hemagglutinin and Neuraminidase.
Int. J. Mol. Sci. 24 1-23, 2023.

Demeter, F., Török, P., Kiss, A., Kovásznai-Oláh, R., Máthéné Szigeti, Z., Baksa, V., Kovács, F., Balla, N., Fenyvesi, F., Váradi, J., Borbás, A., Herczeg, M.: First Synthesis of DBU-Conjugated Cationic Carbohydrate Derivatives and Investigation of Their Antibacterial and Antifungal Activity.
Int. J. Mol. Sci. 24 (4), 1-20, 2023.

Lőrincz, E., Tóth, G., Spolárics, J., Herczeg, M., Hodek, J., Zupkó, I., Minorics, R., Ádám, D., Oláh, A., Zouboulis, C., Weber, J., Nagy, L., Ostorházi, E., Bácskay, I., Borbás, A., Herczegh, P., Bereczki, I.: Mannich-type modifications of (-)-cannabidiol and (-)-cannabigerol leading to new, bioactive derivatives.
Sci. Rep. 13 (1), 19618, 2023.

Demeter, F., Bényei, A., Borbás, A., Herczeg, M.: Synthesis of the Three Most Expensive L-Hexose Thioglycosides from D-Glucose.
Synthesis. 55 (7), 1087-1111, 2023.

Bege, M., Herczeg, M., Bereczki, I., Debreczeni, N., Bényei, A., Herczegh, P., Borbás, A.: Triaza-tricyclanos - synthesis of a new class of tricyclic nucleoside analogues by stereoselective cascade cyclocondensation.
Org. Biomol. Chem. 21 (10), 2213-2219, 2023.

Herczeg, M., Demeter, F., Lisztes, E., Racskó, M., Tóth, I., Timári, I., Bereczky, Z., Kövér, K., Borbás, A.: Synthesis of a Heparinoid Pentasaccharide Containing L-Guluronic Acid Instead of L-Iduronic Acid with Preserved Anticoagulant Activity.
J. Org. Chem. 87 (23), 15830-15836, 2022.

Demeter, F., Bereczki, I., Borbás, A., Herczeg, M.: Synthesis of Four Orthogonally Protected Rare L-Hexose Thioglycosides from D-Mannose by C-5 and C-4 Epimerization.
Molecules. 27 (11), 1-35, 2022.

Balogh, G., Gyöngyösi, T., Timári, I., Herczeg, M., Borbás, A., Sadiq, S., Fehér, K., Kövér, K.: Conformational Analysis of Heparin-Analogue Pentasaccharides by Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulations.
J. Chem Inf. Model. 61 (6), 2926-2936, 2021.

Csávás, M., Herczeg, M., Bajza, I., Borbás, A.: Protecting Group Manipulations in Carbohydrate Synthesis.
In: Comprehensive Glycoscience. Ed.: Joseph J. Barachi Jr, Elsevire, Oxford, 464-524, 2021. ISBN: 9780128194751

Lisztes, E., Mező, E., Demeter, F., Horváth, L., Bősze, S., Tóth, I., Borbás, A., Herczeg, M.: Synthesis and cell growth inhibitory activity of six non-glycosaminoglycan-type heparin-analogue trisaccharides.
ChemMedChem. 16 (9), 1467-1476, 2021.

Demeter, F., Boehlich, G., Borbás, A., Herczeg, M.: Synthesis of an orthogonally protected L-idose derivative using hydroboration/oxidation.
In: Carbohydrate Chemistry Proven Synthetic Methods. Ed.: Pavol Kovác, Paul Kosma, Tanja Wrodnigg, Arnold Stütz, Crc Press-Taylor & Francis Group, Boca Raton, 233-240, 2021. ISBN: 9780815367888

Mező, E., Herczeg, M., Demeter, F., Bereczki, I., Csávás, M., Borbás, A.: Systematic study of regioselective reductive ring opening reactions of 4,6-Ohalobenzylidene acetals of glucopyranosides.
J. Org. Chem. 86 (18), 12973-12987, 2021.

Debreczeni, N., Bege, M., Herczeg, M., Bereczki, I., Batta, G., Herczegh, P., Borbás, A.: Tightly linked morpholino-nucleoside chimeras: new, compact cationic oligonucleotide analogues.
Org. Biomol. Chem. 19 8711-8721, 2021.

Bereczki, I., Herczeg, M.: Laboratory Investigations In Pharmaceutical Chemistry II..
Debreceni Egyetem, Debrecen, 88 p., 2020.

Kelemen, V., Csávás, M., Hotzi, J., Herczeg, M., Poonam, Rathi, B., Herczegh, P., Jain, N., Borbás, A.: Photoinitiated Thiol-Ene Reactions of Various 2,3-Unsaturated O-, C- S- and N-Glycosides: scope and Limitations Study.
Chem.-Asian J. 15 (6), 876-891, 2020.

Demeter, F., Dah-Tsyr Chang, M., Lee, Y., Fu, T., Herczeg, M., Borbás, A.: Synthesis of α-1,2- and α-1,3-linked di-rhamnolipids for biological studies.
Carbohydr. Res. 496 1-17, 2020.

Demeter, F., Chang, M., Lee, Y., Borbás, A., Herczeg, M.: An Efficient Synthesis of the Pentasaccharide Repeating Unit of Pseudomonas aeruginosa Psl Exopolysaccharide.
Synlett. 31 (05), 469-474, 2019.

Szőke, K., Czompa, A., Lekli, I., Szabados-Fürjesi, P., Herczeg, M., Csávás, M., Borbás, A., Herczegh, P., Tósaki, Á.: A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety.
Eur. J. Pharm. Sci. 131 159-166, 2019.

Balogh, G., Gyöngyösi, T., Timári, I., Herczeg, M., Borbás, A., Fehér, K., Kövér, K.: Comparison of Carbohydrate Force Fields Using Gaussian Accelerated Molecular Dynamics Simulations and Development of Force Field Parameters for Heparin-Analogue Pentasaccharides.
J. Chem Inf. Model. 59 (11), 4855-4867, 2019.

Szőke, K., Czompa, A., Lekli, I., Szabados-Fürjesi, P., Herczeg, M., Csávás, M., Borbás, A., Herczegh, P., Tósaki, Á.: Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety.
Data brief. 25 1-10, 2019.

Demeter, F., Balogh, T., Fu, T., Chang, M., Lee, Y., Borbás, A., Herczeg, M.: Preparation of α-l-Rhamnobiosides by Open and Conventional Glycosylations for Studies of the rHPL Lectin.
Synlett. 30 (19), 2185-2192, 2019.

Fu, T., Ng, S., Chen, Y., Lee, Y., Demeter, F., Herczeg, M., Borbás, A., Chiu, C., Lan, C., Chen, C., Dah-Tsyr Chang, M.: Rhamnose Binding Protein as an Anti-Bacterial Agent-Targeting Biofilm of Pseudomonas aeruginosa.
Mar. Drugs. 17 (6), 1-19, 2019.

Malinovská, L., Le Thai, S., Herczeg, M., Vaskova, M., Houser, J., Fujdiarová, E., Komárek, J., Hodek, P., Borbás, A., Wimmerová, M., Csávás, M.: Synthesis of [beta]-D-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential.
Biomolecules. 9 (11), 1-22, 2019.

Farcet, J., Herczeg, M., Christler, A., Kosma, P.: 3-Azidopropyl 2-acetamido-2-deoxy-[alfa]-D-glucopyranoside.
In: Carbohydrate Chemistry Proven Synthetic Methods. Ed.: Pavol Kovác, Christian Vogel, Paul V. Murphy, Crc Press-Taylor & Francis Group, Boca Raton, 295-302, 2018, (Volume 4ISSN ) ISBN: 9780367893156

Herczeg, M., Demeter, F., Balogh, T., Kelemen, V., Borbás, A.: Rapid Synthesis of l-Idosyl Glycosyl Donors from α-Thioglucosides for the Preparation of Heparin Disaccharides.
Eur. J. Org. Chem. 2018 (25), 3312-3316, 2018.

Demeter, F., Gyöngyösi, T., Bereczky, Z., Kövér, K., Herczeg, M., Borbás, A.: Replacement of the L-iduronic acid unit of the anticoagulant pentasaccharide idraparinux by a 6-deoxy-L-talopyranose: synthesis and conformational analysis.
Sci Rep. 8 (1), 1-10, 2018.

Demeter, F., Veres, F., Herczeg, M., Borbás, A.: Short Synthesis of Idraparinux by Applying a 2-O-Methyl-4,6-O-arylmethylene Thioidoside as a 1,2-trans-α-Selective Glycosyl Donor.
Eur. J. Org. Chem. 48 6901-6912, 2018.

Jančaříková, G., Herczeg, M., Fujdiarová, E., Houser, J., Kövér, K., Borbás, A., Wimmerová, M., Csávás, M.: Synthesis of α-L-fucopyranoside-presenting glycoclusters and investigation of their interaction with Photorhabdus asymbiotica lectin (PHL).
Chem.Eur. J. 24 (16), 4055-4068, 2018.

Kicsák, M., Mándi, A., Varga, S., Herczeg, M., Batta, G., Bényei, A., Borbás, A., Herczegh, P.: Tricyclanos: conformationally constrained nucleoside analogues with a new heterotricycle obtained from a D-ribofuranose unit.
Org. Biomol. Chem. 16 (3), 393-401, 2018.

Bege, M., Bereczki, I., Herczeg, M., Kicsák, M., Eszenyi, D., Herczegh, P., Borbás, A.: A low-temperature, photoinduced thiol-ene click reaction: a mild and efficient method for the synthesis of sugar-modified nucleosides.
Org. Biomol. Chem. 15 (43), 9226-9233, 2017.

Mező, E., Eszenyi, D., Varga, E., Herczeg, M., Borbás, A.: A Modular Synthetic Approach to Isosteric Sulfonic Acid Analogues of the Anticoagulant Pentasaccharide Idraparinux.
Molecules. 21 (11), 1497-1515, 2016.

Kondor, Z., Herczeg, M., Borbás, A., Patonay, T., Kónya, K.: Application of Carbohydrates with Methylene or Vinyl Groups in Heck-Mizoroki Cross-Coupling Reactions with O-Heterocycles.
Synlett. 27 (19), 2709-2715, 2016.

Kicsák, M., Bege, M., Bereczki, I., Csávás, M., Herczeg, M., Kupihar, Z., Kovács, L., Borbás, A., Herczegh, P.: A three-component reagent system for rapid and mild removal of O-, N- and S-trityl protecting groups.
Org. Biomol. Chem. 14 (12), 3190-3192, 2016.

Herczeg, M., Mező, E., Molnár, N., Ng, S., Lee, Y., Dah-Tsyr Chang, M., Borbás, A.: Inhibitory Effect of Multivalent Rhamnobiosides on Recombinant Horseshoe Crab Plasma Lectin Interactions with PAO1.
Chem. Asian J. 11 (23), 3398-3413, 2016.

Herczeg, M., Molnár, N., Balogh, T., Mező, E., Borbás, A.: Multivalens ramnobiozid-származékok szintézise és lektinnel való kölcsönhatásuk vizsgálata.
Magy. kém. lapja. 71 (5), 146-149, 2016.

Eszenyi, D., Mándi, A., Herczeg, M., Bényei, A., Komáromi, I., Borbás, A.: Synthesis of C-2- and C-3-Sulfonatomethyl O- and S-Glycosides by Horner-Wadsworth-Emmons Olefination.
Eur. J. Org. Chem. 2016 (22), 3884-3893, 2016.

Herczeg, M., Csávás, M., Bereczki, I., Mező, E., Eszenyi, D., Kicsák, M., Hadházi, Á., Tollas, S., Varga, E., Szilágyi, E., Molnár, J., Bege, M., Pénzes, A., Herczegh, P., Borbás, A.: Gyógyhatású szénhidrátok - a véralvadástól a géncsendesítésig.
Magy. Kém. F. 121 (1), 13-21, 2015.

Herczegh, P., Borbás, A., Herczeg, M., Bereczki, I.: Kémiai biológia.
Debreceni Egyetem, Debrecen, 142 p., 2015.

Bereczki, I., Csávás, M., Gunda, T., Herczeg, M.: Laboratory Investigations in Pharmaceutical Chemistry I..
Debreceni Egyetem, Debrecen, 102 p., 2015.

Herczeg, M., Demeter, F., Mező, E., Pap, M., Borbás, A.: Simultaneous Application of Arylmethylene Acetal and Butane Diacetal Groups for Protection of Hexopyranosides: Synthesis and Chemoselective Ring-Opening Reactions.
Eur. J. Org. Chem. 2015 (26), 5730-5741, 2015.

Csávás, M., Miskovics, A., Szűcs, Z., Rőth, E., Nagy, Z., Bereczki, I., Herczeg, M., Batta, G., Nemes-Nikodém, É., Ostorházi, E., Rozgonyi, F., Borbás, A., Herczegh, P.: Synthesis and antibacterial evaluation of some teicoplanin pseudoaglycon derivatives containing alkyl- and arylthiosubstituted maleimides.
J. Antibiot. 68 (9), 579-585, 2015.

Herczeg, M., Mező, E., Varga, E., Kövér, K., Borbás, A.: Synthesis and anticoagulant activity of 6-sulfonic-acid-containing analogues of idraparinux.
In: Debrecen colloquium on carbohydrates 2015 András Lipták Memorial Conference : Program and abstracts. Ed.: Csávás Magdolna, Debreceni Egyetem, Debrecen, 33, 2015.

Varga, E., Herczeg, M., Mező, E., Borbás, A.: Synthesis of' an idraparinux analogue pentasaccharide monosulfonic acid.
In: Debrecen colloquium on carbohydrates 2015 András Lipták Memorial Conference : Program and abstracts. Ed.: Csávás Magdolna, Debreceni Egyetem, Debrecen, 76, 2015.

Bereczki, I., Herczeg, M., György, B., Naesens, L., Herczegh, P.: Synthesis of a sialic acid derivative of ristocetin aglycone as an inhibitor of influenza virus.
Chem. Pap. 69 (8), 1-5, 2015.

Mező, E., Herczeg, M., Balogh, T., Molnár, N., Borbás, A.: Synthesis of multivalent rhamnobiosides for studying the glycan binding activity of recombinant horse crab plasma lectin.
Debrecen colloquium on carbohydrates 2015 2015 (1), 1, 2015.

Demeter, F., Herczeg, M., Borbás, A.: Synthesis of sulfonic acid-containing maltooligomers with potential antitumor and antimetastatic activity.
In: Debrecen colloquium on carbohydrates 2015 András Lipták Memorial Conference : Program and abstracts. Ed.: Csávás Magdolna, Debreceni Egyetem, Debrecen, 53, 2015. ISBN: 9789634738848

Demeter, F., Herczeg, M., Borbás, A.: Synthesis of sulfonic acid-containing maltooligomers with potential antitumor and antimetastatic activity.

Mező, E., Herczeg, M., Eszenyi, D., Antus, S., Borbás, A.: Antikoaguláns hatású pentaszacharidszulfonsav sorozat moduláris szintézise: problémák és megoldások.
Magy. Kém. Lapja. 69 (6), 184-187, 2014.

Mező, E., Herczeg, M., Eszenyi, D., Borbás, A.: Large-scale synthesis of 6-deoxy-6-sulfonatomethyl glycosides and their application for novel synthesis of a heparinoid pentasaccharide trisulfonic acid of anticoagulant activity.
Carbohydr. Res. 388 19-29, 2014.

Herczeg, M., Mező, E., Eszenyi, D., Antus, S., Borbás, A.: New synthesis of idraparinux, the non-glycosaminoglycan analogue of the antithrombin-binding domain of heparin.
Tetrahedron. 70 (18), 2919-2927, 2014.

Fekete, A., Eszenyi, D., Herczeg, M., Pozsgay, V., Borbás, A.: Preparation of synthetic oligosaccharide-conjugates of poly-[beta]-(1-6)-N-acetyl glucosamine.
Carbohydr. Res. 386 33-40, 2014.

Csávás, M., Demeter, T., Herczeg, M., Timári, I., Kövér, K., Herczegh, P., Borbás, A.: Rapid synthesis of self-assembling 1,2-thiomannobioside glycoconjugates as potential multivalent ligands of mannose-binding lectins.
Tetrahedron Lett. 55 (51), 6983-6986, 2014.

Herczeg, M., Lázár, L., Ohlin, M., Borbás, A.: Regioselective reductive openings of 4,6-O-benzylidene-type acetals using LiAlH4-AlCl3.
In: Carbohydrate Chemistry : Proven Synthetic Methods. Ed.: Gijsbert van der Marel, Jeroen Codee, CRC Press, New York, 9-19, 2014. ISBN: 9781439875940

Herczeg, M., Mező, E., Lázár, L., Fekete, A., Kövér, K., Antus, S., Borbás, A.: Novel syntheses of Idraparinux, the anticoagulant pentasaccharide with indirect selective factor Xa inhibitory activity.
Tetrahedron. 69 (15), 3149-3158, 2013.

Herczeg, M., Mező, E., Eszenyi, D., Lázár, L., Csávás, M., Bereczki, I., Antus, S., Borbás, A.: Synthesis of 6-Sulfonatomethyl Thioglycosides by Nucleophilic Substitution: Methods to Prevent 1 6 Anomeric Group Migration of Thioglycoside 6-O-Triflates.
Eur. J. Org. Chem. 2013 (25), 5570-5573, 2013.

Csávás, M., Herczeg, M., Borbás, A.: Synthesis of S-Linked N-Acetylneuraminic Acid Derivatives via Photoinduced Thiol-ene and Thiol-yne Couplings.
Synlett. 24 (6), 719-722, 2013.

Lázár, L., Csávás, M., Hadházi, Á., Herczeg, M., Tóth, M., Somsák, L., Barna, T., Herczegh, P., Borbás, A.: Systematic study on free radical hydrothiolation of unsaturated monosaccharide derivatives with exo- and endocyclic double bonds.
Org. Biomol. Chem. 11 (32), 5339-5350, 2013.

Herczeg, M., Mező, E., Eszenyi, D., Pataki, R., Borbás, A., Antus, S.: Újabb eredményeink a heparinoid szulfonsavak szintézisében.
Magy. kém. lapja. 68 (9), 264-266, 2013.

Lázár, L., Jánossy, L., Csávás, M., Herczeg, M., Borbás, A., Antus, S.: Selective removal of the (2-naphthyl)methyl protecting group in the presence of p-methoxybenzyl group by catalytic hydrogenation.
Arkivoc. 5 312-325, 2012.

Herczeg, M., Lázár, L., Bereczky, Z., Kövér, K., Timári, I., Kappelmayer, J., Lipták, A., Antus, S., Borbás, A.: Synthesis and Anticoagulant Activity of Bioisosteric Sulfonic-Acid Analogues of the Antithrombin-Binding Pentasaccharide Domain of Heparin.
Chem.-Eur. J. 18 (34), 10643-10652, 2012.

Lázár, L., Csávás, M., Herczeg, M., Herczegh, P., Borbás, A.: Synthesis of S-Linked Glycoconjugates and S-Disaccharides by Thiol-Ene Coupling Reaction of Enoses.
Org. Lett. 14 (17), 4650-4653, 2012.

Májer, G., Csávás, M., Lázár, L., Herczeg, M., Bényei, A., Antus, S., Borbás, A.: Synthesis of sulfonic acid-containing maltose-type keto-oligosaccharides by an iterative approach.
Tetrahedron. 68 (25), 4986-4994, 2012.

Lázár, L., Mező, E., Herczeg, M., Lipták, A., Antus, S., Borbás, A.: Synthesis of the non-reducing end trisaccharide of the antithrombin-binding domain of heparin and its bioisosteric sulfonic acid analogues.
Tetrahedron. 68 (36), 7386-7399, 2012.

Szikra, D., Mándi, A., Borbás, A., Nagy, I., Komáromi, I., Kiss-Szikszai, A., Herczeg, M., Antus, S.: A kinetic study on the reductive opening of the diphenylmethylene acetal in methyl 2,3-O-diphenylmethylene-[alpha]-l-rhamnopyranoside.
Carbohydr. Res. 346 (13), 2004-2006, 2011.

Csávás, M., Májer, G., Herczeg, M., Gálné Remenyik, J., Lázár, L., Mándi, A., Borbás, A., Antus, S.: Investigation of glycosylating properties of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranosyl derivatives: Synthesis of a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide.
Carbohydr. Res. 346 (12), 1527-1533, 2011.

Herczeg, M., Lázár, L., Mándi, A., Borbás, A., Komáromi, I., Lipták, A., Antus, S.: Synthesis of disaccharide fragments of the AT-III binding domain of heparin and their sulfonatomethyl analogues.
Carbohydr. Res. 346 (13), 1827-1836, 2011.

Lázár, L., Herczeg, M., Fekete, A., Borbás, A., Lipták, A., Antus, S.: Synthesis of sulfonic acid analogues of the non-reducing end trisaccharide of the antithrombin binding domain of heparin.
Tetrahedron Lett. 51 (51), 6711-6714, 2010.

Szabó, Z., Herczeg, M., Fekete, A., Batta, G., Borbás, A., Lipták, A., Antus, S.: Synthesis of three regioisomers of the pentasaccharide part of the Skp1 glycoprotein of Dictyostelium discoideum.
Tetrahedron Asymmetry. 20 (6-8), 808-820, 2009.

Herczeg, M., Lázár, L., Borbás, A., Lipták, A., Antus, S.: Toward Synthesis of the Isosteric Sulfonate Analogues of the AT-III Binding Domain of Heparin.
Org. Lett. 11 (12), 2619-2622, 2009.