Tudóstér: Szöőr Árpád publikációi

Nagy, L., Mezősi-Csaplár, M., Rebenku, I., Vereb, G., Szöőr, Á.: Universal CAR T cells targeted to HER2 with a biotin-trastuzumab soluble linker penetrate spheroids and large tumor xenografts that are inherently resistant to trastuzumab mediated ADCC.
Front. Immunol. 15 1-38, 2024.

Barden, M., Holzinger, A., Velas, L., Mezősi-Csaplár, M., Szöőr, Á., Vereb, G., Schütz, G., Hombach, A., Abken, H.: CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation.
Front. Immunol. 14 1-13, 2023.

Mezősi-Csaplár, M., Szöőr, Á., Vereb, G.: CD28 and 41BB Costimulatory Domains Alone or in Combination Differentially Influence Cell Surface Dynamics and Organization of Chimeric Antigen Receptors and Early Activation of CAR T Cells.
Cancers (Basel). 15 (12), 3081-3097, 2023.

Csiki, D., Ababneh, H., Tóth, A., Lente, G., Szöőr, Á., Tóth, A., Fillér, C., Juhász, T., Nagy, B., Balogh, E., Jeney, V.: Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease.
Front. Cardiovasc. Med. 10 1-15, 2023.

Tóth, A., Csiki, D., Nagy, B., Balogh, E., Lente, G., Ababneh, H., Szöőr, Á., Jeney, V.: Daprodustat Accelerates High Phosphate-Induced Calcification Through the Activation of HIF-1 Signaling.
Front. Pharmacol. 13 1-12, 2022.

Cserepes, M., Nelhűbel, G., Meilinger-Dobra, M., Herczeg, A., Türk, D., Hegedűs, Z., Svajda, L., Rásó, E., Ladányi, A., Csikó, K., Kenessey, I., Szöőr, Á., Vereb, G., Remenár, É., Tóvári, J.: EGFR R521K Polymorphism Is Not a Major Determinant of Clinical Cetuximab Resistance in Head and Neck Cancer.
Cancers (Basel). 14 (10), 1-15, 2022.

Bencze, D., Fekete, T., Pfliegler, V., Szöőr, Á., Csoma, E., Szántó, A., Tarr, T., Bácsi, A., Kemény, L., Veréb, Z., Pázmándi, K.: Interactions between the NLRP3-Dependent IL-1β and the Type I Interferon Pathways in Human Plasmacytoid Dendritic Cells.
Int. J. Mol. Sci. 23 (20), 1-34, 2022.

Blokon-Kogan, D., Levi-Mann, M., Malka-Levy, L., Itzhaki, O., Besser, M., Shiftan, Y., Szöőr, Á., Vereb, G., Gross, G., Abken, H., Weinstein-Marom, H.: Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy.
J Immunother Cancer. 10 (9), 1-12, 2022.

Guti, E., Regdon, Z., Sturniolo, I., Kiss, A., Kovács, K., Demény, M., Szöőr, Á., Vereb, G., Szöllősi, J., Hegedűs, C., Polgár, Z., Virág, L.: The multitargeted receptor tyrosine kinase inhibitor sunitinib induces resistance of HER2 positive breast cancer cells to trastuzumab-mediated ADCC.
Cancer Immunol. Immunother. 71 (9), 2151-2168, 2022.

Mezősi-Csaplár, M., Szöllősi, J., Gottschalk, S., Vereb, G., Szöőr, Á.: Cytolytic Activity of CAR T Cells and Maintenance of Their CD4+ Subset Is Critical for Optimal Antitumor Activity in Preclinical Solid Tumor Models.
Cancers (Basel). 13 (17), 1-19, 2021.

Varga, Z., Rácz, E., Türk-Mázló, A., Korodi, M., Szabó, A., Molnár, T., Szöőr, Á., Veréb, Z., Bácsi, A., Koncz, G.: Cytotoxic activity of human dendritic cells induces RIPK1-dependent cell death.
Immunobiology. 226 (1), 1-7, 2021.

Szöőr, Á., Szöllősi, J., Vereb, G.: From antibodies to living drugs: quo vadis cancer immunotherapy?.
Biol. Futura. 72 (1), 85-99, 2021.

Tóth, G., Szöllősi, J., Abken, H., Vereb, G., Szöőr, Á.: A Small Number of HER2 Redirected CAR T Cells Significantly Improves Immune Response of Adoptively Transferred Mouse Lymphocytes against Human Breast Cancer Xenografts.
Int. J. Mol. Sci. 21 (3), 1-11, 2020.

Volpin, V., Michels, T., Sorrentino, A., Menevse, A., Knoll, G., Ditz, M., Milenkovic, V., Chen, C., Rathinasamy, A., Griewank, K., Boutros, M., Haferkamp, S., Berneburg, M., Wetzel, C., Seckinger, A., Hose, D., Goldschmidt, H., Ehrenschwender, M., Witzens-Harig, M., Szöőr, Á., Vereb, G., Khandelwal, N., Beckhove, P.: CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti-PD-L1 Treatment.
Cancer Immunol. Res. 8 1163-1179, 2020.

Szöőr, Á., Tóth, G., Zsebik, B., Szabó, V., Eshhar, Z., Abken, H., Vereb, G.: Trastuzumab Derived HER2-specific CARs for the Treatment of Trastuzumab-Resistant Breast Cancer: CAR T Cells Penetrate and Eradicate Tumors That Are Not Accessible to Antibodies.
Cancer Lett. 484 1-8, 2020.

Méhes, E., Baráth, M., Gulyás, M., Bugyik, E., Geiszt, M., Szöőr, Á., Lányi, Á., Czirok, A.: Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4.
Sci. Rep. 9 (1), 1-13, 2019.

Bosire, R., Nánási, P., Imre, L., Dienes, B., Szöőr, Á., Türk-Mázló, A., Kovács, A., Seidel, R., Vámosi, G., Szabó, G.: Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint.
PLoS One. 14 (11), e0224936, 2019.

Velasquez, M., Szöőr, Á., Vaidya, A., Thakkar, A., Nguyen, T., Wu, M., Liu, H., Gottschalk, S.: CD28 and 41BB Costimulation Enhances the Effector Function of CD19-Specific Engager T Cells.
Cancer Immunol. Res. 5 (10), 860-870, 2017.

Szöőr, Á., Vereb, G.: Kiméra antigénreceptorral módosított T-sejtek: új fegyverek a daganatterápiában.
Immunol. Szle. 9 (2), 4-11, 2017.

Szöőr, Á., Vaidya, A., Velasquez, M., Mei, Z., Galvan, D., Torres, D., Gee, A., Heczey, A., Gottschalk, S.: T Cell-Activating Mesenchymal Stem Cells as a Biotherapeutic for HCC.
Mol. Ther Oncolytics. 28 (6), 69-79, 2017.

Szöőr, Á., Velasquez, M., Bonifant, C., Vaidya, A., Brunetti, L., Gundry, M., Parihar, R., Goodell, M., Gottschalk, S.: Two-pronged Cell Therapy: engineering NK cells to target CD22 and redirect bystander T cells to CD19 for the adoptive immunotherapy of B-cell malignancies.
J. Immunol. 198 (Suppl.), 198,6, 2017.

Bonifant, C., Szöőr, Á., Torres, D., Joseph, N., Velasquez, M., Iwahori, K., Gaikwad, A., Nguyen, T., Arber, C., Song, X., Redell, M., Gottschalk, S.: CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia.
Mol. Ther. 24 (9), 1615-1626, 2016.

Szöőr, Á., Ujlaky-Nagy, L., Tóth, G., Szöllősi, J., Vereb, G.: Cell confluence induces switching from proliferation to migratory signaling by site-selective phosphorylation of PDGF receptors on lipid raft platforms.
Cell. Signal. 28 (2), 81-93, 2016.

Szöőr, Á., Mei, Z., Gee, A., Heczey, A., Gottschalk, S.: T Cell-Activating Mesenchymal Stem Cells as a Biotherapeutic for HCC.
Mol. Ther. 24 (Suppl.), S255-S256, 2016.

Velasquez, M., Torres, D., Iwahori, K., Kakarla, S., Arber, C., Rodriguez-Cruz, T., Szöőr, Á., Bonifant, C., Gerken, C., Cooper, L., Song, X., Gottschalk, S.: T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies.
Sci. Rep. 6 (27130), 1-11, 2016.

Tóth, G., Szöőr, Á., Simon, L., Yarden, Y., Szöllősi, J., Vereb, G.: The combination of trastuzumab and pertuzumab administered at approved doses may delay development of trastuzumab resistance by additively enhancing antibody-dependent cell-mediated cytotoxicity.
mAbs. 8 (7), 1361-1370, 2016.

Nagy, D., Gönczi, M., Dienes, B., Szöőr, Á., Fodor, J., Nagy, Z., Tóth, A., Fodor, T., Bai, P., Szűcs, G., Rusznák, Z., Csernoch, L.: Silencing the KCNK9 potassium channel (TASK-3) gene disturbs mitochondrial function, causes mitochondrial depolarization, and induces apoptosis of human melanoma cells.
Arch. Dermatol. Res. 306 (10), 885-902, 2014.

Nagy, D., Gönczi, M., Nagy, Z., Tóth, A., Dienes, B., Fodor, J., Szűcs, G., Rusznák, Z., Szöőr, Á., Csernoch, L.: Stable gene silencing of TASK-3 channels in melanoma cells induce intrinsic apoptosis.
Acta Physiol. 211 (Suppl.), 40, 2014.

Govers, C., Sebestyén, Z., Roszik, J., van Brakel, M., Berrevoets, C., Szöőr, Á., Panoutsopoulou, K., Broertjes, M., Van, T., Vereb, G., Szöllősi, J., Debets, R.: TCRs genetically linked to CD28 and CD3[epszilon] do not mispair with endogenous TCR chains and mediate enhanced t cell persistence and anti-melanoma activity.
J. Immunol. 193 (10), 5315-5326, 2014.

Pázmándi, K., Kumar, B., Szabó, K., Boldogh, I., Szöőr, Á., Vereb, G., Rajnavölgyi, É., Bácsi, A.: Parlagfű szubpollen partikulák NAD(P)H oxidáz enzimei által termelt reaktív oxigén gyökök hatásainak vizsgálata humán dendritikus sejteken.
Immunol. Szle. 4 (3), 30, 2012.

Pázmándi, K., Kumar, B., Szabó, K., Boldogh, I., Szöőr, Á., Vereb, G., Veres, Á., Lányi, Á., Rajnavölgyi, É., Bácsi, A.: Ragweed subpollen particles of respirable size activate human dendritic cells.
PLoS One. 7 (12), e52085, 2012.

Pázmándi, K., Kumar, B., Szabó, K., Boldogh, I., Szöőr, Á., Vereb, G., Veres, Á., Lányi, Á., Rajnavölgyi, É., Bácsi, A.: Reactive oxygen species generated by NAD(P)H oxidases in ragweed subpollen particles activate human dendritic cells.
Immunology. 137 458, 2012.

Vondalova, B., Jelínková, I., Szöőr, Á., Skender, B., Soucek, K., Horváth, V., Vaculova, A., Andera, L., Sova, P., Szöllősi, J., Hofmanova, J., Vereb, G., Kozubik, A.: Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Carcinogenesis. 32 (1), 42-51, 2011.

Roszik, J., Sebestyén, Z., Govers, C., Guri, Y., Szöőr, Á., Pályiné Krekk, Z., Vereb, G., Nagy, P., Szöllősi, J., Debets, R.: T-cell synapse formation depends on antigen recognition but not CD3 interaction: studies with TCR : zeta, a candidate transgene for TCR gene therapy.
Eur. J. Immunol. 41 (5), 1288-1297, 2011.

Szöőr, Á., Szöllősi, J., Vereb, G.: Rafts and the battleships of defense: the multifaceted microdomains for positive and negative signals in immune cells.
Immunol. Lett. 130 (1-2), 2-12, 2010.

Ujlaky-Nagy, L., Szöőr, Á., Szöllősi, J., Vereb, G.: Cell surface pattern of PDGF receptors affects signalling in glioblastoma cells.
FEBS J. 272 (Suppl1), 230, 2005.