Tudóstér: Rühl Ralph publikációi

Carlsen, H., Ebihara, K., Kuwata, N., Kuwata, K., Aydemir, G., Rühl, R., Blomhoff, R.: A transgenic reporter mouse model for assessment of retinoic acid receptor transcriptional activation.
Int. J. Vitam. Nutr. Res. 93 (1), 29-41, 2023.

Bácsi, A., Lucas, R., Sütő, M., Szklenár, M., Bohn, T., Rühl, R.: An immune-shift induced by lycopene; from an eosinophil-dominant type towards an eosinophil/neutrophil-co-dominant type of airway inflammation.
Food Funct. 13 (12), 6534-6544, 2022.

Lucas, R., Szklenár, M., Mihály, J., Szegedi, A., Töröcsik, D., Rühl, R.: Plasma Levels of Bioactive Vitamin D and A5 Ligands Positively Correlate with Clinical Atopic Dermatitis Markers.
Dermatology. 238 (6), 1076-1083, 2022.

Lucas, R., Mihály, J., Gericke, J., de Lera, Á., Álvarez, S., Veleczki, Z., Töröcsik, D., Rühl, R.: Topical Vitamin D Receptor Antagonist/ Partial-Agonist Treatment Induces Epidermal Hyperproliferation via RAR[gamma] Signaling Pathways.
Dermatology. 237 (2), 197-203, 2021.

Kovács, D., Dull, K., Szegedi, A., Deák, D., Póliska, S., Rühl, R., Zouboulis, C., Töröcsik, D.: Isotretinoin is indirectly effective in sebocytes.
Br. J. Dermatol. 182 (4), 1052-1054, 2020.

Weiss, K., Garcia, A., Marosvölgyi, T., Szklenár, M., Decsi, T., Rühl, R.: Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat.
Eur. J. Nutr. 59 (6), 2759-2769, 2020.

Lucas, R., Mihály, J., Gericke, J., Töröcsik, D., Rühl, R.: Vitamin D signaling in a mouse allergic sensitization model.
Int. J. Vitam. Nutr. Res. 90 (5-6), 385-388, 2020.

Aydemir, G., Domínguez, M., de Lera, Á., Mihály, J., Töröcsik, D., Rühl, R.: Apo-14'-Carotenoic Acid Is a Novel Endogenous and Bioactive Apo-Carotenoid.
Nutrients. 11 (9), 1-11, 2019.

Sarang, Z., Sághy, T., Budai, Z., Ujlaky-Nagy, L., Bedekovics, J., Beke, L., Méhes, G., Nagy, G., Rühl, R., Moise, A., Palczewski, K., Szondy, Z.: Retinol Saturase Knock-Out Mice are Characterized by Impaired Clearance of Apoptotic Cells and Develop Mild Autoimmunity.
Biomolecules. 9 (11), 737, 2019.

Töröcsik, D., Weise, C., Gericke, J., Szegedi, A., Lucas, R., Mihály, J., Worm, M., Rühl, R.: Transcriptomic and lipidomic profiling of eicosanoid/docosanoid signalling in affected and non-affected skin of human atopic dermatitis patients.
Exp. Dermatol. 28 (2), 177-189, 2019.

Bohn, T., Planchon, S., Leclercq, C., Renaut, J., Mihály, J., Béke, G., Rühl, R.: Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.
Food Funct. 9 (7), 3835-3844, 2018.

Lucas, R., Mihály, J., Lowe, G., Graham, D., Szklenár, M., Szegedi, A., Töröcsik, D., Rühl, R.: Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients.
Nutrients. 10 (10), 1-12, 2018.

Tarapcsák, S., Szalóki, G., Telbisz, Á., Gyöngy, Z., Matúz, K., Csősz, É., Nagy, P., Holb, I., Rühl, R., Nagy, L., Szabó, G., Goda, K.: Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein.
Sci Rep. 7 (41376), 1-31, 2017.

Landrier, J., Kasiri, E., Karkeni, E., Mihály, J., Béke, G., Weiss, K., Lucas, R., Aydemir, G., Salles, J., Walrand, S., de Lera, Á., Rühl, R.: Reduced adiponectin expression after high-fat diet is associated with selective up-regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue.
Faseb J. 31 (1), 203-211, 2017.

Dajnoki, Z., Béke, G., Kapitány, A., Mócsai, G., Gáspár, K., Rühl, R., Hendrik, Z., Juhász, I., Zouboulis, C., Bácsi, A., Bíró, T., Töröcsik, D., Szegedi, A.: Sebaceous gland rich skin is characterized by TSLP expression and distinct immune surveillance which is disturbed in rosacea.
J. Invest. Dermatol. 137 (5), 1114-1125, 2017.

Lovászi, M., Mattii, M., Eyerich, K., Gácsi, A., Csányi, E., Kovács, D., Rühl, R., Szegedi, A., Kemény, L., Ståhle, M., Zouboulis, C., Eyerich, S., Töröcsik, D.: Sebum lipids influence macrophage polarization and activation.
Br. J. Dermatol. 177 (6), 1671-1682, 2017.

Dózsa, A., Mihály, J., Dezső, B., Csizmadia, É., Keresztessy, T., Markó, L., Rühl, R., Remenyik, É., Nagy, L.: Decreased peroxisome proliferator-activated receptor [gamma] level and signalling in sebaceous glands of patients with acne vulgaris.
Clin. Exp. Dermatol. 41 (5), 547-551, 2016.

Aydemir, G., Kasiri, Y., Bartók, E., Birta, E., Fröhlich, K., Böhm, V., Mihály, J., Rühl, R.: Lycopene supplementation restores vitamin A deficiency in mice and possesses thereby partial pro-vitamin A activity transmitted via RAR-signaling.
Mol. Nutr. Food Res. 60 (11), 2413-2420, 2016.

Bazhin, A., Bleul, T., de Lera, Á., Werner, J., Rühl, R.: Relationship Between All-trans-13,14-Dihydro Retinoic Acid and Pancreatic Adenocarcinoma.
Pancreas. 45 (6), E29-E31, 2016.

Kovács, D., Lovászi, M., Póliska, S., Oláh, A., Bíró, T., Veres, I., Zouboulis, C., Ståhle, M., Rühl, R., Remenyik, É., Töröcsik, D.: Sebocytes differentially express and secrete adipokines.
Exp. Dermatol. 25 (3), 194-199, 2016.

Mihály, J., Gericke, J., Lucas, R., de Lera, Á., Álvarez, S., Töröcsik, D., Rühl, R.: TSLP expression in the skin is mediated via RAR-RXR pathways.
Immunobiology. 221 (2), 161-165, 2016.

Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Széles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenár, M., Nagy, L., de Lera, Á., Krężel, W.: 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.
PLoS Genet. 11 (6), e1005213-, 2015.

Kiss, B., Szántó, M., Szklenár, M., Brunyánszki, A., Marosvölgyi, T., Sárosi, E., Remenyik, É., Gergely, P., Virág, L., Decsi, T., Rühl, R., Bai, P.: Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity.
Mol. Med. Rep. 11 (4), 2861-2867, 2015.

Mihály, J., Sonntag, D., Krebiehl, G., Szegedi, A., Töröcsik, D., Rühl, R.: Steroid concentrations in atopic dermatitis patients: reduced plasma DHEAS and increased cortisone levels.
Br. J. Dermatol. 172 (1), 285-288, 2015.

Zolberg, R., Harats, D., Harari, A., Ben, -., Bitzur, R., Rühl, R., Shaish, A.: Vitamin A-Deficient Diet Accelerated Atherogenesis in Apolipoprotein E-/- Mice and Dietary [betan]-Carotene Prevents This Consequence.
Biomed Res. Int. 2015 1-9, 2015.

Skazik, C., Amann, P., Heise, R., Marquardt, Y., Czaja, K., Kim, A., Rühl, R., Kurschat, P., Merk, H., Bickers, D., Baron, J.: Downregulation of STRA6 expression in epidermal keratinocytes leads to hyperproliferation-associated differentiation in both in vitro and in vivo skin models.
J. Invest. Dermatol. 134 (6), 1579-1588, 2014.

Weiss, K., Mihály, J., Liebisch, G., Marosvölgyi, T., Garcia, A., Schmitz, G., Decsi, T., Rühl, R.: Effect of high versus low doses of fat and vitamin A dietary supplementation on fatty acid composition of phospholipids in mice.
Genes Nutr. 9 (1), 368, 2014.

Mihály, J., Marosvölgyi, T., Szegedi, A., Köröskényi, K., Lucas, R., Töröcsik, D., Garcia, A., Decsi, T., Rühl, R.: Increased FADS2-Derived n-6 PUFAs and Reduced n-3 PUFAs in Plasma of Atopic Dermatitis Patients.
Skin Pharmacol. Physiol. 27 (5), 242-248, 2014.

Töröcsik, D., Kovács, D., Camera, E., Lovászi, M., Cseri, K., Nagy, G., Molinaro, R., Rühl, R., Tax, G., Szabó, K., Picardo, M., Kemény, L., Zouboulis, C., Remenyik, É.: Leptin promotes proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes.
Br. J. Dermatol. 171 (6), 1326-35, 2014.

Sarang, Z., Joós, G., Garabuczi, É., Rühl, R., Gregory, C., Szondy, Z.: Macrophages engulfing apoptotic cells produce nonclassical retinoids to enhance their phagocytic capacity.
J. Immunol. 192 (12), 5730-5738, 2014.

Joós, G., Sarang, Z., Garabuczi, É., Rühl, R., Szondy, Z.: Macrophages engulfing apoptotic cells produce non-classical retinoids to enhance their phagocytic capacity.
FEBS J. 281 (Suppl.), 141, 2014.

Dózsa, A., Dezső, B., Tóth, I., Bácsi, A., Póliska, S., Camera, E., Picardo, M., Zouboulis, C., Bíró, T., Schmitz, G., Liebisch, G., Rühl, R., Remenyik, É., Nagy, L.: PPARγ-Mediated and Arachidonic Acid-Dependent Signaling is Involved in Differentiation and Lipid Production of Human Sebocytes.
J. Invest. Dermatol. 134 (4), 910-920, 2014.

Gericke, J., Ittensohn, J., Mihály, J., Dubrac, S., Rühl, R.: Allergen-induced dermatitis causes alterations in cutaneous retinoid-mediated signaling in mice.
PLoS One. 8 (8), e71244, 2013.

Szklenár, M., Kalkowski, J., Stangl, V., Lorenz, M., Rühl, R.: Eicosanoids and docosanoids in plasma and aorta of healthy and atherosclerotic rabbits.
J. Vasc. Res. 50 (5), 372-382, 2013.

Király, A., Váradi, T., Hajdu, T., Rühl, R., Galmarini, C., Szöllősi, J., Nagy, P.: Hypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid rafts.
Mar. Drugs. 11 (12), 4858-4875, 2013.

Aydemir, G., Kasiri, Y., Birta, E., Béke, G., Garcia, A., Bartók, E., Rühl, R.: Lycopene-derived bioactive retinoic acid receptors/retinoid-X receptors-activating metabolites may be relevant for lycopene's anti-cancer potential.
Mol. Nutr. Food Res. 57 (5), 739-747, 2013.

Sarang, Z., Garabuczi, É., Joós, G., Kiss, B., Tóth, K., Rühl, R., Szondy, Z.: Macrophages engulfing apoptotic thymocytes produce retinoids to promote selection, differentiation, removal and replacement of double positive thymocytes.
Immunobiology. 218 (11), 1354-1360, 2013.

Rühl, R.: Non-pro-vitamin A and pro-vitamin A carotenoids in atopy development.
Int. Arch. Allergy Immunol. 161 (2), 99-115, 2013.

Zein Elabdeen, H., Mustafa, M., Szklenár, M., Rühl, R., Ali, R., Bolstad, A.: Ratio of pro-resolving and pro-inflammatory lipid mediator precursors as potential markers for aggressive periodontitis.
PLoS One. 8 (8), 2013.

Mihály, J., Gericke, J., Töröcsik, D., Gáspár, K., Szegedi, A., Rühl, R.: Reduced lipoxygenase and cyclooxygenase mediated signaling in PBMC of atopic dermatitis patients.
Prostaglandins Other Lipid Mediat. 107 35-42, 2013.

Gericke, J., Ittensohn, J., Mihály, J., Álvarez, S., Álvarez, R., Töröcsik, D., de Lera, Á., Rühl, R.: Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin.
PLoS One. 8 (4), e62643, 2013.

Aydemir, G., Carlsen, H., Blomhoff, R., Rühl, R.: Lycopene induces retinoic acid receptor transcriptional activation in mice.
Mol. Nutr. Food Res. 56 (5), 702-712, 2012.

Mihály, J., Gericke, J., Aydemir, G., Weiss, K., Carlsen, H., Blomhoff, R., Garcia, J., Rühl, R.: Reduced retinoid signaling in the skin after systemic retinoid-X receptor ligand treatment in mice with potential relevance for skin disorders.
Dermatology. 225 (4), 304-311, 2012.

Grüber, C., Taner, C., Mihály, J., Matricardi, P., Wahn, U., Rühl, R.: Serum Retinoic Acid and Atopy Among Children of Different Ethnic Origin Living in Germany.
J. Pediatr. Gastroenterol. Nutr. 54 (4), 558-560, 2012.

Gouranton, E., Aydemir, G., Reynaud, E., Marcotorchino, J., Malezet, C., Caris-Veyrat, C., Blomhoff, R., Landrier, J., Rühl, R.: Apo-10'-lycopenoic acid impacts adipose tissue biology via the retinoic acid receptors.
Biochim. Biophys. Acta. Mol. Cell Biol. Lipids. 1811 (12), 1105-1114, 2011.

Mihály, J., Gamlieli, A., Worm, M., Rühl, R.: Decreased retinoid concentration and retinoid signalling pathways in human atopic dermatitis.
Exp. Dermatol. 20 (4), 326-330, 2011.

Weiss, K., Mihály, J., Liebisch, G., Marosvölgyi, T., Schmitz, G., Decsi, T., Rühl, R.: Effect of synthetic ligands of PPAR alfa, béta/delta, gamma, RAR, RXR and LXR on the fatty acid composition of phospholipids in mice.
Lipids. 46 (11), 1013-1020, 2011.

Weise, C., Hilt, K., Milovanovic, M., Ernst, D., Rühl, R., Worm, M.: Inhibition of IgE production by docosahexaenoic acid is mediated by direct interference with STAT6 and NFKB pathway in human B cells.
J. Nutr. Biochem. 22 (3), 269-275, 2011.

Reynaud, E., Aydemir, G., Rühl, R., Dangles, O., Caris-Veyrat, C.: Organic synthesis of new putative lycopene metabolites and preliminary investigation of their cell-signaling effects.
J. Agric. Food Chem. 59 (4), 1457-1463, 2011.

Dózsa, A., Dezső, B., Tóth, B., Bácsi, A., Liebisch, G., Schmitz, G., Zouboulis, C., Rühl, R., Bíró, T., Remenyik, É., Nagy, L.: PPAR gamma is a key regulator of sebaceous gland differentiation and proliferation in normal and pathological sebocytes.
J. Invest. Dermatol. 131 S71, 2011.

Dózsa, A., Dezső, B., Tóth, I., Bácsi, A., Liebisch, G., Schmitz, G., Zouboulis, C., Rühl, R., Bíró, T., Remenyik, É., Nagy, L.: PPARg is a key regulator of sebaceous gland differentiation and proliferation in normal and pathological sebocytes.
J. Invest. Dermatol. 131 (2), S71, 2011.

Dózsa, A., Rühl, R., Dezső, B., Tóth, I., Bíró, T., Bácsi, A., Zouboulis, C., Schmitz, G., Seltmann, H., Remenyik, É., Nagy, L.: PUFA molekulák aktiválják a PPAR[gamma] (Peroxiszóma Proliferáció Aktiválta Receptor gamma) molekulát az ép sebocytákban.
Bőrgyógyász. Venerol. Szle. 87 (6), 200, 2011.

Flachs, P., Rühl, R., Hensler, M., Janovska, P., Zouhar, P., Kus, V., Macek Jilkova, Z., Papp, E., Kuda, O., Svobodova, M., Rossmeisl, M., Tsenov, G., Mohamed-Ali, V., Kopecky, J.: Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids.
Diabetologia. 54 (10), 2626-2638, 2011.

Simándi, Z., Bálint, B., Póliska, S., Rühl, R., Nagy, L.: Activation of retinoic acid receptor signaling coordinates lineage commitment of spontaneously differentiating mouse embryonic stem cells in embryoid bodies.
FEBS Lett. 584 (14), 3123-3130, 2010.

Bai, N., He, K., Ibarra, A., Bily, A., Roller, M., Chen, X., Rühl, R.: Article iridoids from fraxinus excelsior with adipocyte differentiation-inhibitory and PPARalfa activation activity.
J. Nat. Prod. 73 (1), 2-6, 2010.

Fritzsche, B., Schuchardt, J., Schmidt, A., Nau, H., Schweigert, F., Rühl, R.: CYP26A1-specific antagonist influence on embryonic implantation, gene expression and endogenous retinoid concentration in rats.
Reprod. Toxicol. 30 (3), 446-451, 2010.

Széles, L., Póliska, S., Nagy, G., Szatmári, I., Szántó, A., Pap, A., Lindstedt, M., Santegoets, S., Rühl, R., Dezső, B., Nagy, L.: Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Mol. Endocrinol. 24 (11), 2218-2231, 2010.

Rühl, R., Taner, C., Schweigert, F., Wahn, U., Grüber, C.: Serum carotenoids and atopy among children of different ethnic origin living in Germany.
Pediatr. Allergy Immunol. 21 (7), 1072-1075, 2010.

Gericke, J., Aydemir, G., Ulbricht, G., Rühl, R.: Statistical calculation of the transition of vitamin A and β-carotene ingestion in the former West and East German regions between 1986 and 1993.
Acta Aliment. 39 (3), 343-356, 2010.

Gericke, J., Gamlieli, A., Weiss, K., Rühl, R.: Comment on "Cutting edge: inhibition of NF-kappa B-mediated TSLP expression by retinoid X receptor".
J. Immunol. 182 (1), 3, 2009.

Gericke, J., Gamlieli, A., Weiss, K., Rühl, R.: Comment on "inhibition of NF-KB-mediated expression by retinoid X receptors".
J. Immunol. 182 182, 2009.

Rühl, R., Mihály, J., Szegedi, A.: Leukotrienes and leukotriene-signaling in atopic dermatitis.
J. Invest. Dermatol. 129 (2), S53, 2009.

Csánky, E., Rühl, R., Scholtz, B., Vaskó, A., Takács, L., Hempel, W.: Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients controls.
Electrophoresis. 30 (7), 1228-1234, 2009.

Rühl, R.: Retinoids, vitamin A and pro-vitamin A carotenoids Regulation of the immune system and allergies.
Pharm. Unserer Zeit. 38 (2), 126-131, 2009.

Koch, C., Dölle, S., Metger, M., Rasche, C., Jungclas, H., Rühl, R., Renz, H., Worm, M.: Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial.
Br. J. Dermatol. 158 (4), 786-792, 2008.

Rühl, R., Koch, C., Marosvölgyi, T., Mihály, J., Schweigert, F., Worm, M., Decsi, T.: Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution.
Br. J. Nutr. 99 (6), 1239-1246, 2008.

Rühl, R., Bub, A., Watzl, B.: Modulation of plasma all-trans retinoic acid concentrations by the consumption of carotenoid-rich vegetables.
Nutrition. 24 (11-12), 1224-1226, 2008.

Kiss, I., Rühl, R., Szegezdi, É., Fritsche, B., Tóth, B., Pongrácz, J., Perlmann, T., Fésüs, L., Szondy, Z.: Retinod receptor-activating ligands are produced within the mouse thymus during postnatal development.
Eur J. Immunol. 38 (1), 147-155, 2008.

Környei, Z., Gócza, E., Rühl, R., Vörös, E., Szabó, B., Orsolits, B., Vágovits, B., Madarász, E.: Astroglia-derived retinoic acid is a key factor in glia-induced neurogenesis.
FASEB J. 21 2459-2509, 2007.

Rühl, R.: Effect of dietary retinoids and carotenoids on immune development.
Proc. Nutr. Soc. 66 (3), 458-469, 2007.

Fritzsche, B., Vermot, J., Neumann, U., Schmidt, A., Schweigert, F., Dollé, P., Rühl, R.: Regulation of expression of theretinoicacidmetabolizingenzyme CYP26A1 inuteri of ovariectomizedmiceaftertreatmentwithovariansteroidhormones.
Mol. Reprod. Dev. 74 (2), 258-264, 2007.

Rühl, R., Garcia, A., Hänel, A., Dahten, A., Herz, U., Worm, M., Schweigert, F.: Role of vitamin A elimination or supplementation diets during postnatal development on the allergic sensitisation in mice.
Mol. Nutr. Food Res. 51 (9), 1173-1187, 2007.

Rühl, R.: Method to determine 4-oxo-retinoic acids, retinoic acids and retinol in serum and cell extracts by liquid chromatography/diode-array detection atmospheric pressure chemical ionisation tandem mass spectrometry.
Rapid Commun. Mass Spectrom. 20 (16), 2497-2504, 2006.

Szatmári, I., Pap, A., Rühl, R., Ma, J., Illarionov, P., Besra, G., Rajnavölgyi, É., Dezső, B., Nagy, L.: PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.
J. Exp. Med. 203 (10), 2351-2362, 2006.

Rühl, R., Fritzsche, B., Vermot, J., Niederreither, K., Neumann, U., Schmidt, A., Schweigert, F., Dollé, P.: Regulation of expression of the retinoic acid-synthesising enzymes retinaldehyde dehydrogenases in the uteri of ovariectomised mice after treatment with oestrogen, gestagen and their combination.
Reprod. Fertil. Dev. 18 (3), 339-345, 2006.

Puvogel, G., Baumrucker, C., Sauerwein, H., Rühl, R., Ontsouka, E., Hammon, H., Blum, J.: Effects of an Enhanced Vitamin A Intake During the Dry Period on Retinoids, Lactoferrin, IGF System, Mammary Gland Epithelial Cell Apoptosis, and Subsequent Lactation in Dairy Cows.
J. Dairy Sci. 88 (5), 1785-1800, 2005.

Rühl, R., Hamscher, G., Garcia, A., Nau, H., Schweigert, F.: Identification of 14-hydroxy-retro-retinol and 4-hydroxy-retinol as endogenous retinoids in rats throughout neonatal development.
Life Sci. 76 (14), 1613-1622, 2005.

Rühl, R.: Induction of PXR-mediated metabolism by beta-carotene.
Biochim. Biophys. Acta. Mol. Basis Dis. 1740 (2), 162-169, 2005.

Garcia, A., Rühl, R., Schweigert, F.: Retinoid Concentrations in the Mouse during Postnatal Development and after Maternal Vitamin A Supplementation.
Ann. Nutr. Metab. 49 (5), 333-341, 2005.

Rogge, B., Itagaki, Y., Fishkin, N., Levi, E., Rühl, R., Yi, S., Nakanishi, K., Hammerling, U.: Retinoylserine and Retinoylalanine, Natural Products of the Moth.
J. Nat. Prod. 68 (10), 1536-1540, 2005.

Rühl, R., Sczech, R., Landes, N., Pfluger, P., Kluth, D., Schweigert, F.: Carotenoids and their metabolites are naturally occurring activators of gene expression via the pregnane X receptor.
Eur. J. Nutr. 43 (6), 336-343, 2004.

Szántó, A., Benkő, S., Szatmári, I., Bálint, B., Furtos, I., Rühl, R., Molnár, S., Csiba, L., Garuti, R., Calandra, S., Larsson, H., Diczfalusy, U., Nagy, L.: Transcriptional Regulation of Human CYP27 Integrates Retinoid, Peroxisome Proliferator-Activated Receptor, and Liver X Receptor Signaling in Macrophages.
Mol. Cell. Biol. 24 (18), 8154-8166, 2004.

Rühl, R., Schweigert, F.: Automated solid-phase extraction and liquid chromatographic method for retinoid determination in biological samples.
J. Chromatogr. B. 798 (2), 309-316, 2003.

Rühl, R., Dahten, A., Schweigert, F., Herz, U., Worm, M.: Inhibition of IgE-Production by Peroxisome Proliferator-Activated Receptor Ligands.
J. Invest. Dermatol. 121 (4), 757-764, 2003.

Rühl, R., Garcia, A., Schweigert, F., Worm, M.: Modulation of Cytokine Production by Low and High Retinoid Diets in Ovalbumin-Sensitized Mice.
Int. J. Vitam. Nutr. Res. 74 (04), 279-284, 2003.

Garcia, A., Rühl, R., Herz, U., Koebnick, C., Schweigert, F., Worm, M.: Retinoid- and carotenoid-enriched diets influence the ontogenesis of the immune system in mice.
Immunology. 110 (2), 180-187, 2003.

Landes, N., Pfluger, P., Kluth, D., Birringer, M., Rühl, R., Böl, G., Glatt, H., Brigelius-Flohé, R.: Vitamin E activates gene expression via the pregnane X receptor.
Biochem. Pharmacol. 65 (2), 269-273, 2003.

Rühl, R., Sass, J., Nau, H., Klug, S.: Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity.
Arch. Toxicol. 75 (8), 497-504, 2001.

Rühl, R., Plum, C., Elmazar, M., Nau, H.: Embryonic subcellular distribution of 13-cis- and all-trans-retinoic acid indicates differential cytosolic/nuclear localization.
Toxicol. Sci. 63 (1), 82-89, 2001.

Elmazar, M., Rühl, R., Nau, H.: Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARalpha- or RARgamma-selective agonist with a RXR-selective agonist.
Toxicol. Appl. Pharmacol. 170 (1), 2-9, 2001.

Rühl, R., Thiel, R., Lacker, T., Strohschein, S., Albert, K., Nau, H.: Synthesis, high-performance liquid chromatography-nuclear magnetic resonance characterization and pharmacokinetics in mice of CD271 glucuronide.
J. Chrom. B Biomed. Sci. Appl. 757 (1), 101-109, 2001.

Krätke, R., Rühl, R., Kirschbaum, F., Nau, H.: All- trans -retinoic acid and all- trans -retinoyl-beta-d -glucuronide alter the development of axolotl embryos ( Ambystoma mexicanum ) in vitro.
Arch. Toxicol. 74 (3), 173-180, 2000.

Zouboulis, C., Seltmann, H., Sass, J., Rühl, R., Plum, C., Hettmannsperger, U., Blume-Peytavi, U., Nau, H., Orfanos, C.: Retinoid Signaling by all-trans Retinoic Acid and all-trans Retinoyl-beta-D-Glucuronide Is Attenuated by Simultaneous Exposure of Human Keratinocytes to Retinol.
J. Invest. Dermatol. 112 (2), 157-164, 1999.

Zouboulis, C., Xia, L., Akamatsu, H., Seltmann, H., Fritsch, M., Hornemann, S., Rühl, R., Chen, W., Nau, H., Orfanos, C.: The human sebocyte culture model provides new insights into development and management of seborrhoea and acne.
Dermatology. 196 (1), 21-31, 1998.

Rühl, R., Nau, H.: Determination of adapalene (CD271/differin®) and retinol in plasma and tissue by on-line solid-phase extraction and HPLC analysis.
Chromatographia. 45 (1), 269-274, 1997.

Sass, J., Zimmermann, B., Rühl, R., Nau, H.: Effects of all-trans-retinoyl-beta-d-glucuronide and all-trans-retinoic acid on chondrogenesis and retinoid metabolism in mouse limb bud mesenchymal cells in vitro.
Arch. Toxicol. 71 (3), 142-150, 1997.

Elmazar, M., Rühl, R., Reichert, U., Shroot, B., Nau, H.: RARalpha-Mediated Teratogenicity in Mice Is Potentiated by an RXR Agonist and Reduced by an RAR Antagonist: dissection of Retinoid Receptor-Induced Pathways.
Toxicol. Appl. Pharmacol. 146 (1), 21-28, 1997.

Nau, H., Elmazar, M., Rühl, R., Thiel, R., Sass, J.: All-trans-retinoyl-beta-glucuronide is a potent teratogen in the mouse because of extensive metabolism to all-trans-retinoic acid.
Teratology. 54 (3), 150-156, 1996.

Foerster, M., Sass, J., Rühl, R., Nau, H.: Comparative studies on effects of all-trans-retinoic acid and all-trans-retinoyl-beta-d-glucuronide on the development of foetal mouse thymus in an organ culture system.
Toxicol. Vitro. 10 (1), 7-15, 1996.