Tudóstér: Hegyi Bence publikációi

Chen-Izu, Y., Hegyi, B., Jian, Z., Horváth, B., Shaw, J., Bányász, T., Izu, L.: Innovative techniques and new insights: studying cardiac ionic currents and action potentials in physiologically relevant conditions.
Physiol. Mini Rev. 16 (3), 22-34, 2023.

Izu, L., Shimkunas, R., Jian, Z., Hegyi, B., Kazemi-Lari, M., Baker, A., Shaw, J., Bányász, T., Chen-Izu, Y.: Emergence of Mechano-Sensitive Contraction Autoregulation in Cardiomyocytes.
Life (Basel). 11 (6), 503, 2021.

Shimkunas, R., Hegyi, B., Jian, Z., Shaw, J., Kazemi-Lari, M., Mitra, D., Leach, J., Li, X., Jaradeh, M., Balardi, N., Chen, Y., Escobar, A., Baker, A., Bossuyt, J., Bányász, T., Chiamvimonvat, N., Lam, K., Bers, D., Izu, L., Chen-Izu, Y.: Mechanical Load Regulates Excitation-Ca2+ Signaling-Contraction in Cardiomyocyte.
Circ.Res. 128 (6), 772-774, 2021.

Hegyi, B., Chen-Izu, Y., Izu, L., Rajamani, S., Belardinelli, L., Bers, D., Bányász, T.: Balance Between Rapid Delayed Rectifier K+ Current and Late Na+ Current on Ventricular Repolarization: an Effective Antiarrhythmic Target?.
Circ.-Arrhythmia Electrophysiol. 13 (4), 336-349, 2020.

Hegyi, B., Chen-Izu, Y., Izu, L., Bányász, T.: Altered K+ current profiles underlie cardiac action potential shortening in hyperkalemia and [beta]-adrenergic stimulation.
Can. J. Physiol. Pharmacol. 97 (8), 773-780, 2019.

Hegyi, B., Morotti, S., Liu, C., Ginsburg, K., Bossuyt, J., Belardinelli, L., Izu, L., Chen-Izu, Y., Bányász, T., Grandi, E., Bers, D.: Enhanced Depolarization Drive in Failing Rabbit Ventricular Myocytes.
Circ.-Arrhythmia Electrophysiol. 12 (3), e007061, 2019.

Hegyi, B., Bányász, T., Izu, L., Belardinelli, L., Bers, D., Chen-Izu, Y.: [beta]-adrenergic regulation of late Na+ current during cardiac action potential is mediated by both PKA and CaMKII.
J. Mol. Cell. Cardiol. 123 168-179, 2018.

Sala, L., Hegyi, B., Bartolucci, C., Altomare, C., Rocchetti, M., Váczi, K., Mostacciuolo, G., Szentandrássy, N., Severi, S., Nánási, P., Zaza, A.: Action potential contour contributes to species differences in repolarization response to [béta]-adrenergic stimulation.
Europace. 20 (9), 1543-1552, 2018.

Hegyi, B., Bossuyt, J., Griffiths, L., Shimkunas, R., Coulibaly, Z., Jian, Z., Grimsrud, K., Sondergaard, C., Ginsburg, K., Chiamvimonvat, N., Belardinelli, L., Varró, A., Papp, G., Pollesello, P., Levijoki, J., Izu, L., Boyd, W., Bányász, T., Bers, D., Chen-Izu, Y.: Complex electrophysiological remodeling in postinfarction ischemic heart failure.
Proc. Natl. Acad. Sci. U. S. A. 115 (13), E3036-E3044, 2018.

Jian, Z., Chen, Y., Hegyi, B., Bányász, T., Coulibaly, Z., Shimkunas, R., Chiamvimonvat, N., Lam, K., Izu, L., Chen-Izu, Y.: Mechanical Load Effects on Cardiomyocyte Action Potential, Cacium Transient, and Contraction Revealed by using a Novel Patch-Clamp-in-Gel Technology.
Biophys. J. 114 (3), 620a, 2018.

Veress, R., Baranyai, D., Hegyi, B., Kistamás, K., Dienes, C., Magyar, J., Bányász, T., Nánási, P., Szentandrássy, N., Horváth, B.: Transient receptor potential melastatin 4 channel inhibitor 9-phenanthrol inhibits K+ but not Ca2+ currents in canine ventricular myocytes.
Can. J. Physiol. Pharmacol. 96 (10), 1022-1029, 2018.

Hegyi, B., Horváth, B., Váczi, K., Gönczi, M., Kistamás, K., Ruzsnavszky, F., Veress, R., Izu, L., Chen-Izu, Y., Bányász, T., Magyar, J., Csernoch, L., Nánási, P., Szentandrássy, N.: Ca2+-activated Cl- current is antiarrhythmic by reducing both spatial and temporal heterogeneity of cardiac repolarization.
J. Mol. Cell. Cardiol. 109 27-37, 2017.

Magyar, J., Horváth, B., Váczi, K., Hegyi, B., Gönczi, M., Dienes, B., Kistamás, K., Bányász, T., Baczkó, I., Varró, A., Seprényi, G., Csernoch, L., Nánási, P., Szentandrássy, N.: Calcium Activated Chloride Current in Mammalian Ventricular Myocytes.
Biophys. J. 112 (3), 36a, 2017.

Szentandrássy, N., Hegyi, B., Horváth, B., Váczi, K., Gönczi, M., Dienes, B., Kistamás, K., Veress, R., Ruzsnavszky, F., Bányász, T., Magyar, J., Baczkó, I., Varró, A., Seprényi, G., Csernoch, L., Nánási, P.: Recent advances in research of cardiac calcium-activated chloride channels.
Acta Physiol. 221 (S713), 22, 2017.

Chen-Izu, Y., Izu, L., Hegyi, B., Bányász, T.: Recording of Ionic Currents Under Physiological Conditions: action Potential-Clamp and 'Onion-Peeling' Techniques.
In: Modern Tools of Biophysics, Handbook of Modern Biophysics. Ed.: Jue, Thomas, Springer Science+Business Media LLC, London, 31-48, 2017. ISBN: 9781493967131

Magyar, J., Kistamás, K., Váczi, K., Hegyi, B., Horváth, B., Bányász, T., Nánási, P., Szentandrássy, N.: Concept of relative variability of cardiac action potential duration and its test under various experimental conditions.
Gen. Physiol. Biophys. 35 (1), 55-62, 2016.

Hegyi, B., Bányász, T., Shannon, T., Chen-Izu, Y., Izu, L.: Electrophysiological Determination of Submembrane Na+ Concentration in Cardiac Myocytes.
Biophys. J. 111 (6), 1304-1315, 2016.

Horváth, B., Váczi, K., Hegyi, B., Gönczi, M., Dienes, B., Kistamás, K., Bányász, T., Magyar, J., Baczkó, I., Varró, A., Seprényi, G., Csernoch, L., Nánási, P., Szentandrássy, N.: Sarcolemmal Ca2+-entry through L-type Ca2+ channels controls the profile of Ca2+-activated Cl- current in canine ventricular myocytes.
J. Mol. Cell. Cardiol. 97 125-139, 2016.

Váczi, K., Hegyi, B., Ruzsnavszky, F., Kistamás, K., Horváth, B., Bányász, T., Nánási, P., Szentandrássy, N., Magyar, J.: 9-Anthracene carboxylic acid is more suitable than DIDS for characterization of calcium-activated chloride current during canine ventricular action potential.
Naunyn-Schmiedebergs Arch. Pharmacol. 388 (1), 87-100, 2015.

Kistamás, K., Szentandrássy, N., Hegyi, B., Váczi, K., Ruzsnavszky, F., Horváth, B., Bányász, T., Nánási, P., Magyar, J.: Changes in intracellular calcium concentration influence beat-to-beat variability of action potential duration in canine ventricular myocytes.
J. Physiol. Pharmacol. 66 (1), 73-81, 2015.

Szentmiklósi, J., Szentandrássy, N., Hegyi, B., Horváth, B., Magyar, J., Bányász, T., Nánási, P.: Chemistry, physiology, and pharmacology of [béta]-adrenergic Mechanisms in the heart: why are [béta]-blocker antiarrhythmics superior?.
Curr. Pharm. Design. 21 (8), 1030-1041, 2015.

Szentandrássy, N., Nagy, D., Hegyi, B., Magyar, J., Bányász, T., Nánási, P.: Class IV antiarrhythmic agents: new compounds using an old strategy.
Curr. Pharm. Design. 21 (8), 977-1010, 2015.

Szentandrássy, N., Kistamás, K., Hegyi, B., Horváth, B., Ruzsnavszky, F., Váczi, K., Magyar, J., Bányász, T., Varró, A., Nánási, P.: Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes.
Pflügers Arch. 467 (7), 1431-1443, 2015.

Horváth, B., Hegyi, B., Kistamás, K., Váczi, K., Bányász, T., Magyar, J., Szentandrássy, N., Nánási, P.: Cytosolic calcium changes affect the incidence of early afterdepolarizations in canine ventricular myocytes.
Can. J. Physiol. Pharmacol. 93 (7), 527-534, 2015.

Hegyi, B., Chen-Izu, Y., Jian, Z., Shimkunas, R., Izu, L., Bányász, T.: KN-93 inhibits IKr in mammalian cardiomyocytes.
J. Mol. Cell. Cardiol. 89 (Part), 173-176, 2015.

Kistamás, K., Hegyi, B., Váczi, K., Horváth, B., Bányász, T., Magyar, J., Szentandrássy, N., Nánási, P.: Oxidative shift in tissue redox potential increases beat-to-beat variability of action potential duration.
Can. J. Physiol. Pharmacol. 93 (7), 563-568, 2015.

Szentmiklósi, J., Galajda, Z., Cseppentő, Á., Gesztelyi, R., Susán, Z., Hegyi, B., Nánási, P.: The janus face of adenosine: antiarrhythmic and proarrhythmic actions.
Curr. Pharm. Design. 21 (8), 965-976, 2015.

Sala, L., Hegyi, B., Bartolucci, C., Altomare, C., Rocchetti, M., Mostacciuolo, G., Severi, S., Szentandrássy, N., Nánási, P., Zaza, A.: Action Potential Shape Differences Set Species-Dependent [béta]-Adrenergic Stimulation Response.
Biophys. J. 106 (2_Suppl_1), 119a, 2014.

Ruzsnavszky, F., Hegyi, B., Kistamás, K., Váczi, K., Horváth, B., Szentandrássy, N., Bányász, T., Nánási, P., Magyar, J.: Asynchronous activation of calcium and potassium currents by isoproterenol in canine ventricular myocytes.
Naunyn-Schmiedebergs Arch. Pharmacol. 387 (5), 457-467, 2014.

Bodnár, D., Geyer, N., Ruzsnavszky, O., Oláh, T., Hegyi, B., Sztretye, M., Fodor, J., Dienes, B., Balogh, Á., Papp, Z., Szabó, L., Müller, G., Csernoch, L., Szentesi, P.: Hypermuscular mice with mutation in the myostatin gene display altered calcium signaling.
J. Physiol.-London. 592 (6), 1353-1365, 2014.

Váczi, K., Hegyi, B., Ruzsnavszky, F., Kistamás, K., Horváth, B., Szentandrássy, N., Bányász, T., Nánási, P., Magyar, J.: The short term beat-to-beat variability of action potential duration depends on the length of action potential and intracellular calcium.
Acta Physiol. 211 (s697), 80, 2014.

Horváth, B., Bányász, T., Jian, Z., Hegyi, B., Kistamás, K., Nánási, P., Izu, L., Chen-Izu, Y.: Dynamics of the late Na+ current during cardiac action potential and its contribution to afterdepolarizations.
J. Mol. Cell. Cardiol. 64 59-68, 2013.

Kistamás, K., Szentandrássy, N., Hegyi, B., Ruzsnavszky, F., Váczi, K., Bárándi, L., Horváth, B., Szebeni, A., Magyar, J., Bányász, T., Kecskeméti, V., Nánási, P.: Effects of pioglitazone on cardiac ion currents and action potential morphology in canine ventricular myocytes.
Eur. J. Pharmacol. 710 (1-3), 10-19, 2013.

Sala, L., Hegyi, B., Bartolucci, C., Altomare, C., Rocchetti, M., Mostacciuolo, G., Severi, S., Szentandrássy, N., Nánási, P., Zaza, A.: Effects of species-dependent differences in action potential shape in setting β-adrenergic-stimulation induced current.
Comput. Cardiol. 40 381-384, 2013.

Szabó, L., Szentandrássy, N., Kistamás, K., Hegyi, B., Ruzsnavszky, F., Váczi, K., Horváth, B., Magyar, J., Bányász, T., Pál, B., Nánási, P.: Effects of tacrolimus on action potential configuration and transmembrane ion currents in canine ventricular cells.
Naunyn-Schmiedebergs Arch. Pharmacol. 386 (3), 239-246, 2013.

Csernoch, L., Bodnár, D., Ruzsnavszky, O., Geyer, N., Hegyi, B., Dienes, B., Sztretye, M., Szentesi, P.: Myostatin Deficient Mice Display Altered Calcium Signaling.
Biophys. J. 104 (2), 289a, 2013.

Hegyi, B., Komáromi, I., Nánási, P., Szentandrássy, N.: Selectivity problems with drugs acting on cardiac Na+ and Ca2+ channels.
Curr. Med. Chem. 20 (20), 2552-2571, 2013.

Hegyi, B., Komáromi, I., Kistamás, K., Ruzsnavszky, F., Váczi, K., Horváth, B., Magyar, J., Bányász, T., Nánási, P., Szentandrássy, N.: Tetrodotoxin Blockade on Canine Cardiac L-Type Ca2+ Channels Depends on pH and Redox Potential.
Mar Drugs. 11 (6), 2140-2153, 2013.

Szentandrássy, N., Papp, F., Hegyi, B., Bartók, Á., Krasznai, Z., Nánási, P.: Tetrodotoxin blocks native cardiac L-type calcium channels but not CaV1.2 channels expressed in HEK cells.
J.Physiol Pharmacol. 64 (6), 807-810, 2013.

Farkas, V., Szentandrássy, N., Bárándi, L., Hegyi, B., Ruzsnavszky, F., Ruzsnavszky, O., Horváth, B., Bányász, T., Magyar, J., Márton, I., Nánási, P.: Interaction between Ca2+ channel blockers and isoproterenol on L-type Ca2+ current in canine ventricular cardiomyocytes.
Acta Physiol. 206 (1), 42-50, 2012.

Szentandrássy, N., Farkas, V., Bárándi, L., Hegyi, B., Ruzsnavszky, F., Horváth, B., Bányász, T., Magyar, J., Márton, I., Nánási, P.: Role of action potential configuration and the contribution of Ca2+ and K+ currents to isoprenaline-induced changes in canine ventricular cells.
Br. J. Pharmacol. 167 (3), 599-611, 2012.

Hegyi, B., Bárándi, L., Komáromi, I., Papp, F., Horváth, B., Magyar, J., Bányász, T., Krasznai, Z., Szentandrássy, N., Nánási, P.: Tetrodotoxin blocks L-type Ca2+ channels in canine ventricular cardiomyocytes.
Pflügers Arch. 464 (2), 167-174, 2012.

Szentandrássy, N., Harmati, G., Farkas, V., Horváth, B., Hegyi, B., Magyar, J., Szénási, G., Márton, I., Nánási, P.: Modified cAMP derivatives: powerful tools in heart research.
Curr. Med. Chem. 18 (24), 3729-3736, 2011.