Tudóstér: Uray Iván Péter publikációi

Jambrovics, K., Póliska, S., Scholtz, B., Uray, I., Balajthy, Z.: ATO Increases ROS Production and Apoptosis of Cells by Enhancing Calpain-Mediated Degradation of the Cancer Survival Protein TG2.
Int. J. Mol. Sci. 24 (13), 1-11, 2023.

Kola, J., Turarova, B., Csige, D., Sipos, Á., Varga, L., Gergely, B., Refai, F., Uray, I., Docsa, T., Uray, K.: Stretch-Induced Down-Regulation of HCN2 Suppresses Contractile Activity.
Molecules. 28 (11), 1-14, 2023.

Jambrovics, K., Botó, P., Pap, A., Sarang, Z., Kolostyák, Z., Czimmerer, Z., Szatmári, I., Fésüs, L., Uray, I., Balajthy, Z.: Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death.
Cell Death Dis. 14 (3), 1-10, 2023.

Jdeed, S., Lengyel, M., Uray, I.: Redistribution of the SWI/SNF Complex Dictates Coordinated Transcriptional Control over Epithelial-Mesenchymal Transition of Normal Breast Cells through TGF-[béta] Signaling.
Cells. 11 (17), 1-15, 2022.

Jdeed, S., Erdős, E., Bálint, B., Uray, I.: The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling.
Mol. Cancer Res. 20 (7), 1071-1082, 2022.

Uray, I., Uray, K.: Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface.
Int. J. Mol. Sci. 22 (21), 1-23, 2021.

Szivos, L., Virga, J., Hortobágyi, T., Zahuczky, G., Uray, I., Jenei, A., Bognár, L., Árkosy, P., Klekner, Á.: Az inváziós spektrum prognosztikai jelentősége glioblastomában.
Ideggyogy. Szle. 73 (9-10), 317-325, 2020.

Jambrovics, K., Uray, I., Keillor, J., Fésüs, L., Balajthy, Z.: Benefits of Combined All-Trans Retinoic Acid and Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia Cells and Further Enhancement by Inhibition of Atypically Expressed Transglutaminase 2.
Cancers (Basel). 12 (3), 648-, 2020.

Kocsis, J., Szekanecz, É., Bassam, A., Uhlyarik, A., Pápai, Z., Rubovszky, G., Mezősi, E., Rucz, K., Garai, I., Nagy, E., Uray, I., Horváth, Z.: First Line Sorafenib Treatment for Metastatic Medullary Thyroid Cancer: efficacy and Safety Analysis.
Exp. Clin. Endocrinol. Diabetes. 127 (4), 240-246, 2019.

Jambrovics, K., Uray, I., Keresztessy, Z., Keillor, J., Fésüs, L., Balajthy, Z.: Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-kB activation.
Haematol-Hematol. J. 104 (3), 505-515, 2019.

Chowdhury, P., Powell, R., Stephan, C., Uray, I., Talley, T., Karki, M., Tripathi, D., Park, Y., Mancini, M., Davies, P., Dere, R.: Bexarotene: a Novel Modulator of AURKA and the Primary Cilium in VHL-deficient Cells.
J. Cell Sci. 131 1-12, 2018.

Zhang, L., Shen, J., Yin, Y., Peng, Y., Wang, L., Hsieh, H., Shen, Q., Brown, P., Tao, K., Uray, I., Peng, G.: Identifying cell cycle modulators that selectively target aridia deficiency using high-throughput image-based screening.
SLAS Discovery. 1 (1), 1-14, 2017.

Zhang, L., Peng, Y., Uray, I., Shen, J., Wang, L., Peng, X., Brown, P., Tu, W., Peng, G.: Natural product [béta]-thujaplicin inhibits homologous recombination repair and sensitizes cancer cells to radiation therapy.
DNA Repair. 60 89-101, 2017.

Uray, I., Dmitrovsky, E., Brown, P.: Retinoids and Rexinoids in Cancer Prevention: From Laboratory to Clinic.
Semin. Oncol. 43 (1), 49-64, 2016.

Shepherd, J., Uray, I., Mazumdar, A., Tsimelzon, A., Savage, M., Hilsenbeck, S., Brown, P.: The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression.
Oncotarget. 7 (11), 1-16, 2016.

Uray, I., Rodenberg, J., Zhang, Y., Hill, J., Brown, P.: Abstract 2804: The thiazolidinedione pioglitazone enhances the cancer preventive activity of the rexinoid LG100268 in Her2/neu induced breast cancer.
Cancer Res. 75 (15), 2804, 2015.

Shen, J., Peng, Y., Wei, L., Zhang, W., Yang, L., Lan, L., Kapoor, P., Ju, Z., Mo, Q., Shih, I., Uray, I., Wu, X., Brown, P., Shen, X., Mills, G., Peng, G.: ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors.
Cancer Discov. 5 (7), 752-767, 2015.

Batra, N., Speers, C., Uray, I., Mazumdar, A., Tsimelzon, A., Hilsenbeck, S., Mills, G., Brown, P.: Abstract 3299: Maternal embryonic leucine zipper kinase is critical for the growth and migration of triple negative breast cancer cells.
Cancer Res. 74 (19), 3299-3299, 2014.

Xiong, A., Chen, H., Yang, Z., Cai, G., Wang, L., Ding, C., Xu, G., Wild, C., Ye, N., Uray, I., Zhou, J., Shen, Q.: Abstract 3805: Anticancer agent HJC0416 inhibits the growth of breast cancer xenografts via downregulating STAT3 signaling.
Cancer Res. 74 (19), 3805-3805, 2014.

Sárvári, A., Veréb, Z., Uray, I., Fésüs, L., Balajthy, Z.: Atypical antipsychotics induce both proinflammatory and adipogenic gene expression in human adipocytes in vitro.
Biochem. Biophys. Res. Commun. 450 (4), 1383-1389, 2014.

Hartman, Z., Tsimelzon, A., Uray, I., Hill, J., Zhang, Y., Mazumdar, A., Hilsenbeck, S., Chang, J., Mills, G., Brown, P.: Abstract 4862: Autocrine secreted IL-6 and IL-8 play critical and non-redundant roles in basal-like breast cancer cell transformation and growth in vitro and in vivo.
Cancer Res. 72 (8), 4862-4862, 2012.

Wang, C., Uray, I., Mazumdar, A., Mayer, J., Brown, P.: SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE).
Breast Cancer Res. Treat. 134 (1), 101-115, 2012.

Uray, I., Rodenberg, J., Bissonnette, R., Brown, P., Mancini, M.: Cancer-Preventive Rexinoid Modulates Neutral Lipid Contents of Mammary Epithelial Cells through a Peroxisome Proliferator-Activated Receptor [gamma]-Dependent Mechanism.
Molecular Pharmacology. 81 (2), 228-238, 2011.

Uray, I., Brown, P.: Chemoprevention of hormone receptor-negative breast cancer: new approaches needed.
Recent Results Cancer Res. 188 147-162, 2011.

Szafran, A., Hartig, S., Sun, H., Uray, I., Szwarc, M., Shen, Y., Mediwala, S., Bell, J., McPhaul, M., Mancini, M., Marcelli, M.: Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: a High Content Analysis Approach Leading to Personalized Medicine.
PLoS One. 4 (12), e8179-, 2009.

Rodenberg, J., Uray, I., Bissonnette, R., Brown, P.: Identification of Critical Transducers of Rexiniod-Mediated Growth Suppression in Normal Breast Cells.
Cancer Res. 69 (24), 3134, 2009.

Uray, I., Shen, Q., Seo, H., Kim, H., Lamph, W., Bissonnette, R., Brown, P.: Rexinoid-induced Expression of IGFBP-6 Requires RAR?-dependent Permissive Cooperation of Retinoid Receptors and AP-1.
J. Biol. Chem. 284 (1), 345-353, 2008.

Shen, Q., Uray, I., Li, Y., Zhang, Y., Hill, J., Xu, X., Young, M., Gunther, E., Hilsenbeck, S., Colburn, N., Chodosh, L., Brown, P.: Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor-Negative Mammary Tumors.
Cancer Prevention Research. 1 (1), 45-55, 2008.

Shen, Q., Uray, I., Li, Y., Krisko, T., Strecker, T., Kim, H., Brown, P.: The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors.
Oncogene. 27 366-377, 2007.

Srinivas, H., Xia, D., Moore, N., Uray, I., Kim, H., Ma, L., Weigel, N., Brown, P., Kurie, J.: Akt phosphorylates and suppresses the transactivation of retinoic acid receptor [alfa].
Biochem. J. 395 (3), 653-662, 2006.

Kim, H., Kong, G., DeNardo, D., Li, Y., Uray, I., Pal, S., Mohsin, S., Hilsenbeck, S., Bissonnette, R., Lamph, W., Johnson, K., Brown, P.: Identification of Biomarkers Modulated by the Rexinoid LGD1069 (Bexarotene) in Human Breast Cells Using Oligonucleotide Arrays.
Cancer Res. 66 (24), 12009-12018, 2006.

Uray, I., Brown, P.: Prevention of breast cancer: current state of the science and future opportunities.
Expert Opin. Investig. Drugs. 15 (12), 1583-1600, 2006.

Shen, Q., Zhang, Y., Uray, I., Hill, J., Kim, H., Lu, C., Young, M., Gunther, E., Hilsenbeck, S., Chodosh, L., Colburn, N., Brown, P.: The AP-1 transcription factor regulates postnatal mammary gland development.
Dev. Biol. 2952006.

Uray, I., Liang, Y., Hyder, S.: Estradiol down-regulates CD36 expression in human breast cancer cells.
Cancer Lett. 207 (1), 101-107, 2004.

Sharma, S., Adrogue, J., Golfman, L., Uray, I., Lemm, J., Youker, K., Noon, G., Frazier, O., Taegtmeyer, H.: Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.
Faseb J. 18 (14), 1692-1700, 2004.

Szántó, A., Narkar, V., Shen, Q., Uray, I., Davies, P., Nagy, L.: Retinoid X receptors: x-ploring their (patho)physiological functions.
Cell Death Differ. 11 126-143, 2004.

Uray, I., Connelly, J., Frazier, O., Taegtmeyer, H., Davies, P.: Mechanical unloading increases caveolin expression in the failing human heart.
Cardiovasc. Res. 59 (1), 57-66, 2003.

Razeghi, P., Young, M., Ying, J., Depre, C., Uray, I., Kolesar, J., Shipley, G., Moravec, C., Davies, P., Frazier, O., Taegtmeyer, H.: Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading.
Cardiology. 97 (4), 203-209, 2002.

Uray, I., Connelly, J., Thomázy, V., Shipley, G., Vaughn, W., Frazier, O., Taegtmeyer, H., Davies, P.: Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart.
J. Heart Lung Transplant. 21 (7), 771-782, 2002.

Uray, I., Connelly, J., Frazier, O., Taegtmeyer, H., Davies, P.: Altered expression of tyrosine kinase receptors Her2/neu and GP130 following left ventricular assist device (LVAD) placement in patients with heart failure.
J. Heart Lung Transplant. 20 (2), 210, 2001.

Uray, I., Davies, P., Fésüs, L.: Pharmacological separation of the expression of tissue transglutaminase and apoptosis after chemotherapeutic treatment of HepG2 cells.
Mol. Pharmacol. 59 (6), 1388-1394, 2001.

Piredda, L., Amendola, A., Colizzi, V., Davies, P., Farrace, M., Fraziano, M., Gentile, V., Uray, I., Piacentini, M., Fésüs, L.: Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.
Cell Death Differ. 4 (6), 463-472, 1997.

Fésüs, L., Szondy, Z., Uray, I.: Probing the molecular program of apoptosis by cancer chemopreventive agents.
J. Cell. Biochem. Suppl. Suppl. 22 151-161, 1995.