Tudóstér: Nagy Gergely publikációi

Nagy, G., Bojcsuk, D., Tzerpos, P., Silye-Cseh, T., Nagy, L.: Lineage-determining transcription factor-driven promoters regulate cell type-specific macrophage gene expression.
Nucleic Acids Res. [Epub ahead of print]2024.

Domokos, A., Varga, Z., Jambrovics, K., Caballero-Sánchez, N., Szabó, E., Nagy, G., Scholtz, B., Halász, L., Váradi, E., Bene, K., Türk-Mázló, A., Bácsi, A., Jeney, V., Szebeni, G., Nagy, L., Czimmerer, Z.: The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages.
Front. Immunol. 14 1-20, 2023.

Patsalos, A., Halász, L., Medina-Serpas, M., Berger, W., Dániel, B., Tzerpos, P., Kiss, M., Nagy, G., Fischer, C., Simándi, Z., Varga, T., Nagy, L.: A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
J. Exp. Med. 219 (1), 1-38, 2022.

Göczi, L., Csumita, M., Horváth, A., Nagy, G., Póliska, S., Pigni, M., Thelemann, C., Dániel, B., Mianesaz, H., Varga, T., Sen, K., Raghav, S., Schoggins, J., Nagy, L., Acha-Orbea, H., Meissner, F., Reith, W., Széles, L.: A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.
J. Immun. 209 (10), 1930-1941, 2022.

Fadel, L., Rehó, B., Volkó, J., Bojcsuk, D., Kolostyák, Z., Nagy, G., Müller, G., Simándi, Z., Hegedűs, É., Szabó, G., Tóth, K., Nagy, L., Vámosi, G.: Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor.
J. Biol. Chem. 295 (29), 10045-10061, 2020.

Bojcsuk, D., Nagy, G., Bálint, B.: Alternatively Constructed Estrogen Receptor Alpha-Driven Super-Enhancers Result in Similar Gene Expression in Breast and Endometrial Cell Lines.
Int. J. Mol. Sci. 21 1-18, 2020.

Nagy, G., Nagy, L.: Motif grammar: the basis of the language of gene expression.
Computational and Structural Biotechnology Journal. 18 2026-2032, 2020.

Csumita, M., Csermely, A., Horváth, A., Nagy, G., Monori, F., Göczi, L., Orbea, H., Reith, W., Széles, L.: Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.
Nucleic Acids Res. 48 (2), 589-604, 2020.

Dániel, B., Czimmerer, Z., Halász, L., Botó, P., Kolostyák, Z., Póliska, S., Berger, W., Tzerpos, P., Nagy, G., Horváth, A., Hajas, G., Silye-Cseh, T., Nagy, A., Sauer, S., Francois-Deleuze, J., Szatmári, I., Bácsi, A., Nagy, L.: The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Genes Dev. 34 (21-22), 1474-1492, 2020.

Nagy, G., Dániel, B., Cuaranta-Monroy, I., Nagy, L.: Unraveling the Hierarchy of cis and trans Factors That Determine the DNA Binding by Peroxisome Proliferator-Activated Receptor γ.
Mol. Cell. Biol. 40 (7), 1-20, 2020.

Patsalos, A., Tzerpos, P., Halász, L., Nagy, G., Pap, A., Giannakis, N., Lyroni, K., Koliaraki, V., Pintye, É., Dezső, B., Kollias, G., Spilianakis, C., Nagy, L.: The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration.
J. Immunol. 203 (6), 1532-1547, 2019.

Czimmerer, Z., Horváth, A., Dániel, B., Nagy, G., Cuaranta-Monroy, I., Kiss, M., Kolostyák, Z., Póliska, S., Steiner, L., Giannakis, N., Varga, T., Nagy, L.: Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches.
Biochim. Biophys. Acta. Gene Regul. Mech. 1861 (1), 14-28, 2018.

Czimmerer, Z., Nagy, Z., Nagy, G., Horváth, A., Silye-Cseh, T., Kriston, Á., Jonás, D., Sauer, S., Steiner, L., Dániel, B., Deleuze, J., Nagy, L.: Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Mol. Cell. Endocrinol. 471 63-74, 2018.

Dániel, B., Nagy, G., Horváth, A., Czimmerer, Z., Cuaranta-Monroy, I., Póliska, S., Hays, T., Sauer, S., Francois-Deleuze, J., Nagy, L.: The IL-4/STAT6/PPAR[gamma] signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Nucleic Acids Res. 46 (9), 4425-4439, 2018.

Dániel, B., Nagy, G., Czimmerer, Z., Horváth, A., Hammers, D., Cuaranta-Monroy, I., Póliska, S., Tzerpos, P., Kolostyák, Z., Hays, T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Bálint, B., Sweeney, H., Nagy, L.: The Nuclear Receptor PPAR[gamma] Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.
Immunity. 49 (4), 615-626, 2018.

Czimmerer, Z., Dániel, B., Horváth, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M., Cuaranta-Monroy, I., Simándi, Z., Steiner, L., Nagy, B., Póliska, S., Bankó, C., Bacsó, Z., Schulman, I., Sauer, S., Deleuze, J., Allen, J., Benkő, S., Nagy, L.: The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.
Immunity. 48 (1), 75-90, 2018.

Bojcsuk, D., Nagy, G., Bálint, B.: Inducible super-enhancers are organized based on canonical signal-specific transcription factor binding elements.
Nucleic Acids Res. 45 (7), 3693-3706, 2017.

Kiss, M., Czimmerer, Z., Nagy, G., Bieniasz-Krzywiec, P., Ehling, M., Pap, A., Póliska, S., Botó, P., Tzerpos, P., Horváth, A., Kolostyák, Z., Dániel, B., Szatmári, I., Mazzone, M., Nagy, L.: Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism.
Proc. Natl. Acad. Sci. U. S. A. 114 (40), 10725-10730, 2017.

Varga, T., Mounier, R., Patsalos, A., Gogolák, P., Peloquin, M., Horváth, A., Pap, A., Dániel, B., Nagy, G., Pintye, É., Póliska, S., Cuvellier, S., Ben Larbi, S., Sansbury, B., Spite, M., Brown, C., Chazaud, B., Nagy, L.: Macrophage PPAR[gamma], a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration.
Immunity. 45 (5), 1038-1051, 2016.

Nagy, G., Czipa, E., Steiner, L., Nagy, T., Pongor, S., Nagy, L., Barta, E.: Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA.
BMC Genomics. 17 (637), 1-9, 2016.

Czimmerer, Z., Varga, T., Kiss, M., Vázquez, C., Doan-Xuan, Q., Rückerl, D., Tattikota, S., Yan, X., Nagy, Z., Dániel, B., Póliska, S., Horváth, A., Nagy, G., Varallyay, É., Poy, M., Allen, J., Bacsó, Z., Abreu-Goodger, C., Nagy, L.: The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Genome Med. 8 (1), 1-22, 2016.

Cuaranta-Monroy, I., Simándi, Z., Kolostyák, Z., Doan-Xuan, Q., Póliska, S., Horváth, A., Nagy, G., Bacsó, Z., Nagy, L.: Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid.
Stem Cell Res. 13 (1), 88-97, 2014.

Dániel, B., Nagy, G., Hah, N., Horváth, A., Czimmerer, Z., Póliska, S., Gyuris, T., Keirsse, J., Gysemans, C., Van Ginderachter, J., Bálint, B., Evans, R., Barta, E., Nagy, L.: The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages.
Genes Dev. 28 (14), 1562-1577, 2014.

Dániel, B., Nagy, G., Nagy, L.: The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet?.
FEBS Lett. 588 (15), 2379-2391, 2014.

Nagy, G., Dániel, B., Jonás, D., Nagy, L., Barta, E.: A novel method to predict regulatory regions based on histone mark landscapes in macrophages.
Immunobiology. 218 (11), 1416-1427, 2013.

Széles, L., Póliska, S., Nagy, G., Szatmári, I., Szántó, A., Pap, A., Lindstedt, M., Santegoets, S., Rühl, R., Dezső, B., Nagy, L.: Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Mol. Endocrinol. 24 (11), 2218-2231, 2010.