Tudóstér: Széles Lajos István publikációi

Göczi, L., Csumita, M., Horváth, A., Nagy, G., Póliska, S., Pigni, M., Thelemann, C., Dániel, B., Mianesaz, H., Varga, T., Sen, K., Raghav, S., Schoggins, J., Nagy, L., Acha-Orbea, H., Meissner, F., Reith, W., Széles, L.: A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.
J. Immun. 209 (10), 1930-1941, 2022.

Kerekes, V., Sándor, I., Nagy, D., Ozogány, K., Göczi, L., Ibler, B., Széles, L., Barta, Z.: Trends in demography, genetics, and social structure of Przewalski's horses in the Hortobagy National Park, Hungary over the last 22 years.
Glob. Ecol. Conserv. 25 e01407, 2021.

Csumita, M., Csermely, A., Horváth, A., Nagy, G., Monori, F., Göczi, L., Orbea, H., Reith, W., Széles, L.: Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.
Nucleic Acids Res. 48 (2), 589-604, 2020.

Márton, É., Beke-Varga, A., Széles, L., Göczi, L., Penyige, A., Nagy, B., Szilágyi, M.: The Cell-Free Expression of MiR200 Family Members Correlates with Estrogen Sensitivity in Human Epithelial Ovarian Cells.
Int. J. Mol. Sci. 21 (24), 1-19, 2020.

Kerekes, V., Ozogány, K., Sándor, I., Végvári, Z., Czető, C., Nyírő, B., Szabados, T., Széles, L., Barta, Z.: Analysis of habitat use, activity, and body condition scores of Przewalski's horses in Hortobagy National Park, Hungary.
Nat. Conserv. Res. 4 (Suppl.2), 31-40, 2019.

Penyige, A., Márton, É., Soltész, B., Szilágyi, M., Póka, R., Lukács, J., Széles, L., Nagy, B.: Circulating miRNA Profiling in Plasma Samples of Ovarian Cancer Patients.
Int. J. Mol. Sci. 20 (18), E4533, 2019.

Horváth, A., Dániel, B., Széles, L., Cuaranta-Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simándi, Z., Póliska, S., Giannakis, N., Raineri, E., Gut, I., Nagy, B., Nagy, L.: Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals.
Nucleic Acids Res. 47 (6), 2778-2792, 2019.

Piaszyk-Borychowska, A., Széles, L., Csermely, A., Chiang, H., Wesoly, J., Lee, C., Nagy, L., Bluyssen, H.: Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFkB to Enhance Pro-inflammatory Transcription.
Front. Immunol. 10 1-20, 2019.

Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Széles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenár, M., Nagy, L., de Lera, Á., Krężel, W.: 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.
PLoS Genet. 11 (6), e1005213-, 2015.

Széles, L., Meissner, F., Dunand-Sauthier, I., Thelemann, C., Hersch, M., Singovski, S., Haller, S., Gobet, F., Fuertes Marraco, S., Mann, M., Garcin, D., Acha-Orbea, H., Reith, W.: TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State.
J. Immunol. 195 (3), 1025-1033, 2015.

Nagy, Z., Ross, J., Rodriguez, G., Bálint, B., Széles, L., Nagy, L., Kirken, R.: Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells.
PLoS One. 8 (2), e57326, 2013.

Gyöngyösi, A., Szatmári, I., Pap, A., Dezső, B., Pos, Z., Széles, L., Varga, T., Nagy, L.: RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells.
J. Lipid Res. 54 (9), 2458-2474, 2013.

Fuertes Marraco, S., Grosjean, F., Duval, A., Rosa, M., Lavanchy, C., Ashok, D., Haller, S., Otten, L., Steiner, Q., Descombes, P., Luber, C., Meissner, F., Mann, M., Széles, L., Reith, W., Acha-Orbea, H.: Novel Murine Dendritic Cell Lines: a Powerful Auxiliary Tool for Dendritic Cell Research.
Front. Immunol. 3 1-25, 2012.

Nagy, L., Szántó, A., Szatmári, I., Széles, L.: Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response.
Physiol. Rev. 92 (2), 739-789, 2012.

Póliska, S., Csánky, E., Szántó, A., Szatmári, I., Meskó, B., Széles, L., Dezső, B., Scholtz, B., Podani, J., Kilty, I., Takács, L., Nagy, L.: Chronic Obstructive Pulmonary Disease-Specific Gene Expression Signatures of Alveolar Macrophages as well as Peripheral Blood Monocytes Overlap and Correlate with Lung Function.
Respiration. 81 (6), 499-510, 2011.

Bálint, B., Meskó, B., Nagy, L., Lányi, Á., Scholtz, B., Széles, L., Varga, T.: Molekuláris medicina alapjai.
Debreceni Egyetem, Debrecen, 85 p., 2011.

Nakken, B., Varga, T., Szatmári, I., Széles, L., Gyöngyösi, A., Illarionov, P., Dezső, B., Gogolák, P., Rajnavölgyi, É., Nagy, L.: Peroxisome proliferator-activated receptor [gamma]-regulated cathepsin D is required for lipid antigen presentation by dendritic cells.
J. Immunol. 187 (1), 240-247, 2011.

Töröcsik, D., Baráth, M., Benkő, S., Széles, L., Dezső, B., Póliska, S., Hegyi, Z., Homolya, L., Szatmári, I., Lányi, Á., Nagy, L.: Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli.
J. Immunol. 184 (10), 5456-5464, 2010.

Töröcsik, D., Széles, L., Paragh, G., Rákosy, Z., Bárdos, H., Nagy, L., Balázs, M., Inbal, A., Ádány, R.: Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophages.
Thromb. Haemost. 104 (4), 709-717, 2010.

Széles, L., Póliska, S., Nagy, G., Szatmári, I., Szántó, A., Pap, A., Lindstedt, M., Santegoets, S., Rühl, R., Dezső, B., Nagy, L.: Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Mol. Endocrinol. 24 (11), 2218-2231, 2010.

Szántó, A., Bálint, B., Nagy, Z., Barta, E., Dezső, B., Pap, A., Széles, L., Póliska, S., Oros, M., Evans, R., Barak, Y., Schwabe, J., Nagy, L.: STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPAR[gamma]-Regulated Gene Expression in Macrophages and Dendritic Cells.
Immunity. 3 (5), 699-712, 2010.

Széles, L., Keresztes, G., Töröcsik, D., Balajthy, Z., Krenács, L., Póliska, S., Steinmeyer, A., Zuegel, U., Pruenster, M., Rot, A., Nagy, L.: 1,25 dihidroxyvitamin D3 Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.
J. Immunol. 182 (4), 2047-2083, 2009.

Széles, L., Töröcsik, D., Nagy, L.: PPARγ in immunity and inflammation: cell types and diseases.
Biochim. Biophys. Acta. Mol. Cell Biol. Lipids. 1771 (8), 1014-1030, 2007.

Széles, L., Töröcsik, D., Nagy, L.: At the crossroad of lipid metabolism and inflammation.
BIF Futura. 21 79-85, 2006.

Szatmári, I., Vámosi, G., Brázda, P., Bálint, B., Benkő, S., Széles, L., Jeney, V., Özvegy-Laczka, C., Szántó, A., Barta, E., Balla, J., Sarkadi, B., Nagy, L.: Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells.
J. Biol. Chem. 281 (33), 23812-23823, 2006.