Tudóstér: Juhász László publikációi

Homolya, L., Mathomes, R., Varga, L., Docsa, T., Juhász, L., Hayes, J., Somsák, L.: Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors.
Int. J. Mol. Sci. 25 (9), 1-21, 2024.

József, J., Somsák, L., Tóth, M., Juhász, L.: [2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones.
Eur. J. Org. Chem. 26 (12), 1-10, 2023.

Juhász-Tóth, É., Malecz, Á., Tóth, M., Homolya, Á., Kaszás, T., Somsák, L., Juhász, L.: 2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction.
New J. Chem. 47 (42), 19376-19388, 2023.

Homolya, Á., Jedlóczki, I., Ábrahám, A., Somsák, L., Tóth, M., Juhász, L.: Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions.
Carbohydr. Res. 529 1-12, 2023.

József, J., Somsák, L., Juhász, L.: Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók.
Magy. Kém. F. 129 (3-4), 147-154, 2023.

Kaszás, T., Szakács, B., Juhász-Tóth, É., Cservenyák, I., Kovács, T., Juhász, L., Somsák, L., Tóth, M.: Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles.
European Journal of Organic Chemistry 2022 (42), e202201103, 2022.

Kaszás, T., Baráth, B., Balázs, B., Blága, T., Juhász, L., Somsák, L., Tóth, M.: Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids.
Molecules. 27 (6), 1-31, 2022.

Homolya, L., Antal, D., Nagy, M., Juhász-Tóth, É., Tóth, M., Bényei, A., Somsák, L., Juhász, L.: Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions.
Carbohydr. Res. 519 1-10, 2022.

Homolya, L., Juhász, L., Somsák, L.: Halogen addition to some 1-C-substituted pyranoid glycals.
Carbohydr. Res. 504 1-11, 2021.

Nagy, L., Béke, F., Juhász, L., Kovács, T., Juhász-Tóth, É., Docsa, T., Tóth, A., Gergely, P., Somsák, L., Bai, P.: Glycogen phosphorylase inhibitor, 2,3-bis[(2E)-3-(4-hydroxyphenyl)prop-2-enamido] butanedioic acid (BF142), improves baseline insulin secretion of MIN6 insulinoma cells.
PLoS One. 15 (9), 1-15, 2020.

József, J., Debreczeni, N., Eszenyi, D., Borbás, A., Juhász, L., Somsák, L.: Synthesis and photoinitiated thiol-ene reactions of exo-mannals - a new route to C-beta-d-mannosyl derivatives.
RSC Adv. 10 (57), 34825-34836, 2020.

Somsák, L., Bokor, É., Juhász, L., Kun, S., Lázár, L., Juhász-Tóth, É., Tóth, M.: New syntheses towards C-glycosyl type glycomimetics.
Pure Appl. Chem. 91 (7), 1159-1175, 2019.

József, J., Juhász, L., Somsák, L.: Thio-click reaction of 2-deoxy-exo-glycals towards new glycomimetics: stereoselective synthesis of C-2-deoxy-D-glycopyranosyl compounds.
New J. Chem. 43 (15), 5670-5686, 2019.

Kyriakis, E., Solovou, T., Kun, S., Czifrák, K., Szőcs, B., Juhász, L., Bokor, É., Stravodimos, G., Kantsadi, A., Chatzileontiadou, D., Skamnaki, V., Somsák, L., Leonidas, D.: Probing the [beta]-pocket of the active site of human liver glycogen phosphorylase with 3-(C-[beta]-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorganic Chem. 77 485-493, 2018.

Lázár, L., Juhász, L., Batta, G., Borbás, A., Somsák, L.: Unprecedented [beta]-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals.
New J. Chem. 41 (3), 1284-1292, 2017.

Juhász, L.: Bruckner-termi előadás: Glükopiranozil-oxadiazol- és triazolkarboxamidok mint GP-inhibitorok : szintézis, enzimkinetika és szerkezet-hatás összefüggések.
Magy. kém. lapja. 70 (9), 278-280, 2015.

Begum, J., Varga, G., Docsa, T., Gergely, P., Hayes, J., Juhász, L., Somsák, L.: Computationally motivated synthesis and enzyme kinetic evaluation of N-([beta]-D-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors.
Med. Chem. Commun. 6 (1), 80-89, 2015.

József, J., Juhász, L., Illyés, T., Csávás, M., Borbás, A., Somsák, L.: Photoinitiated hydrothiolation of pyranoid exo-glycals: the d-galacto and d-xylo cases.
Carbohydr. Res. 413 63-69, 2015.

Kun, S., Bokor, É., Varga, G., Szőcs, B., Páhi, A., Czifrák, K., Tóth, M., Juhász, L., Docsa, T., Gergely, P., Somsák, L.: New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4- triazoles, nanomolar inhibitors of glycogen phosphorylase.
Eur. J. Med. Chem. 76 567-579, 2014.

Juhász, L., Varga, G., Sztankovics, A., Béke, F., Docsa, T., Kiss-Szikszai, A., Gergely, P., Kóňa, J., Tvaroška, I., Somsák, L.: Structure-activity relationships of glycogen phosphorylase inhibitor FR258900 and its analogues: a combined synthetic, enzyme kinetics, and computational study.
ChemPlusChem. 79 (11), 1558-1568, 2014.

Polyák, M., Varga, G., Szilágyi, B., Juhász, L., Docsa, T., Gergely, P., Begum, J., Hayes, J., Somsák, L.: Synthesis, enzyme kinetics and computational evaluation of N-(β-d-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors.
Bioorg. Med. Chem. 21 (18), 5738-5747, 2013.

Varga, G., Docsa, T., Gergely, P., Juhász, L., Somsák, L.: Synthesis of tartaric acid analogues of FR258900 and their evaluation as glycogen phosphorylase inhibitors.
Bioorg. Med. Chem. Lett. 23 (6), 1789-1792, 2013.

Somsák, L., Bokor, É., Czifrák, K., Juhász, L., Tóth, M.: Carbohydrate Derivatives and Glycomimetic Compounds in Established and Investigational Therapies of Type 2 Diabetes Mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes. Ed.: Marc B. Zimering, InTech Open Access Publisher, Rijeka, 103-126, 2011.

Somsák, L., Bokor, É., Czifrák, K., Juhász, L., Tóth, M.: Carbohydrate derivatives and glycomimetic compounds in established and investigational therapies of type 2 diabetes mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes / Mark B. Zimering, InTech, Rijeka, 103-126, 2011. ISBN: 9789533075907

Czakó, Z., Docsa, T., Gergely, P., Juhász, L., Antus, S.: Synthesis and glycogen phosphorylase inhibitor activity of funtionalized 1,4-benzodioxanes.
Pharmazie. 65 (4), 235-238, 2010.

Czakó, Z., Juhász, L., Kenéz, Á., Czifrák, K., Somsák, L., Docsa, T., Gergely, P., Antus, S.: Synthesis and glycogen phosphorylase inhibitory activity of N-(beta-D-glucopyranosyl)amides possessing 1,4-benzodioxane moiety.
Bioorg. Med. Chem. 17 (18), 6738-6741, 2009.

Berényi, S., Patonay, T., Juhász, L.: Szerves Kémiai Praktikum II..
Debreceni Egyetemi Kiadó, Debrecen, 92 p., 2009. ISBN: 9789634733010

Juhász, L., Docsa, T., Brunyánszki, A., Gergely, P., Antus, S.: Synthesis and glycogen phosphorylase inhibitor activity of 2,3-dihydrobenzo[1,4]dioxin derivatives.
Bioorg. Med. Chem. 15 (12), 4048-4056, 2007.

Kenéz, Á., Lestár, Z., Lenkey, B., Juhász, L., Antus, S.: Természetes eredetű O- és C-prenilezett flavanonok szintézise és antifungális aktivitásuk vizsgálata.
Acta Pharm. Hung. 77 (1), 17-22, 2007.

Gulácsi, K., Juhász-Tóth, É., Juhász, L., Somsák, L., Tóth, M.: Szerves kémiai praktikum III..
Debreceni Egyetem Kossuth Egyetemi Kiadó, Debrecen, 331 p., 2006. ISBN: 9789634732464

Kónya, K., Kurtán, T., Kiss-Szikszai, A., Juhász, L., Antus, S.: A general CD-method for the configurational assignment of erythro-8.4'-oxyneolign-8'-enes.
Arkivoc. 13 72-78, 2004.

Antus, S., Gulácsi, K., Juhász, L., Kiss, L., Kurtán, T.: Synthesis of Naturally Occurring O-heterocyclic Compounds of Biological Activity.
Pure Appl. Chem. 76 (5), 1025-1032, 2004.

Kenéz, Á., Juhász, L., Antus, S.: A simple synthesis of selinone, an antifungal component of Monotes engleri.
Heterocycl. Commun. 8 (6), 543-548, 2002.

Juhász, L., Visy, J., Simonyi, M., Krohn, K., Antus, S.: Lipase-Catalyzed Kinetic Resolution of (+-)-trans-2-(4-Hydroxy-3-methoxyphenyl)-3-hydroxymethyl-7-methoxy-2,3-dihydrobenzo[b]furan.
Tetrahedron Asymmetry. 13 (11), 1219-1222, 2002.

Juhász, L., Szilágyi, L., Antus, S., Visy, J., Zsila, F., Simonyi, M.: New Insight into the Mechanism of Hypervalent Iodine Oxidation of Flavanones.
Tetrahedron. 58 (21), 4261-4265, 2002.

Antus, S., Kurtán, T., Juhász, L., Kiss, L., Hollósi, M., Májer, Z.: Chiroptical Properties of 2,3-Dihydro[b]furan and Chromane Chromophores in Naturally Occurring O-Heterocycles.
Chirality. 13 (8), 493-506, 2001.

Juhász, L., Dinya, Z., Gunda, T., Antus, S.: A New Approach for the Synthesis of Naturally Occurring Dihydrobenzo[b]furan-Type Neolignans of Potential Biological Activity.
Tetrahedron Lett. 41 (14), 2491-2494, 2000.