Tudóstér: GINOP-2.3.2-15-2016-00020 publikációi

Skopál, A., Ujlaki, G., Gerencsér, A., Bankó, C., Bacsó, Z., Ciruela, F., Virág, L., Haskó, G., Kókai, E.: Adenosine A2A Receptor Activation Regulates Niemann-Pick C1 Expression and Localization in Macrophages.
Curr. Issues Mol. Biol. 45 (6), 4948-4969, 2023.

Guti, E., Bede, Á., Váróczy, C., Hegedűs, C., Demény, M., Virág, L.: High-Content Screening Assay for the Identification of Antibody-Dependent Cellular Cytotoxicity Modifying Compounds.
JoVE. 198 1-12, 2023.

Skopál, A., Kéki, T., Tóth, P., Csóka, B., Koscsó, B., Németh, Z., Antonioli, L., Ivessa, A., Ciruela, F., Virág, L., Haskó, G., Kókai, E.: Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling.
J. Biol. Chem. 298 (5), 1-18, 2022.

Hajnády, Z., Nagy-Pénzes, M., Demény, M., Kovács, K., El-Hamoly, T., Maléth, J., Hegyi, P., Polgár, Z., Hegedűs, C., Virág, L.: OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis.
Biomedicines. 10 (10), 1-17, 2022.

Jdeed, S., Lengyel, M., Uray, I.: Redistribution of the SWI/SNF Complex Dictates Coordinated Transcriptional Control over Epithelial-Mesenchymal Transition of Normal Breast Cells through TGF-[béta] Signaling.
Cells. 11 (17), 1-15, 2022.

Jdeed, S., Erdős, E., Bálint, B., Uray, I.: The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling.
Mol. Cancer Res. 20 (7), 1071-1082, 2022.

Tóth, E., Erdődi, F., Kiss, A.: Activation of Myosin Phosphatase by Epigallocatechin-Gallate Sensitizes THP-1 Leukemic Cells to Daunorubicin.
ACAMC. 21 (9), 1092-1098, 2021.

Zákány, F., Szabó, M., Batta, G., Kárpáti, L., Mándity, I., Fülöp, P., Varga, Z., Panyi, G., Nagy, P., Kovács, T.: An [omega]-3, but Not an [omega]-6 Polyunsaturated Fatty Acid Decreases Membrane Dipole Potential and Stimulates Endo-Lysosomal Escape of Penetratin.
Front. Cell. Dev. Biol. 9 1-17, 2021.

Angyal, Á., Pénzes, Z., Alimohammadi, S., Horváth, D., Takács, L., Vereb, G., Zsebik, B., Bíró, T., Tóth, K., Lisztes, E., Tóth, I., Oláh, A., Szöllősi, A.: Anandamide Concentration-Dependently Modulates Toll-Like Receptor 3 Agonism or UVB-Induced Inflammatory Response of Human Corneal Epithelial Cells.
Int. J. Mol. Sci. 22 (15), 7776, 2021.

Nagyné Szabó, Á., Nagy, P.: I Am the Alpha and the ... Gamma, and the G. Calibration of Intensity-Based FRET Measurements.
Cytom. Part A. 99 (4), 369-371, 2021.

Vörös, O., Panyi, G., Hajdu, P.: Immune Synapse Residency of Orai1 Alters Ca2+ Response of T Cells.
Int. J. Mol. Sci. 22 (21), 1-19, 2021.

Kiss, A., Csíkos, C., Regdon, Z., Polgár, Z., Virág, L., Hegedűs, C.: NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death.
Int. J. Mol. Sci. 22 (16), 1-17, 2021.

El-Hamoly, T., Hajnády, Z., Nagy-Pénzes, M., Bakondi, E., Regdon, Z., Demény, M., Kovács, K., Hegedűs, C., Abd El-Rahman, S., Szabó, É., Maléth, J., Hegyi, P., Virág, L.: Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis.
Int. J. Mol. Sci. 22 (7), 1-15, 2021.

Batta, G., Kárpáti, L., Henrique, G., Tóth, G., Tarapcsák, S., Kovács, T., Zákány, F., Mándity, I., Nagy, P.: Statin-boosted cellular uptake and endosomal escape of penetratin due to reduced membrane dipole potential.
Br. J. Pharmacol. 178 (18), 3667-3681, 2021.

Demény, M., Virág, L.: The PARP enzyme family and the hallmarks of cancer. Part 1. Cell intrinsic hallmarks.
Cancers (Basel). 13 1-28, 2021.

Henn, L., Szabó, A., Imre, L., Román, Á., Ábrahám, A., Vedelek, B., Nánási, P., Boros, I.: Alternative linker histone permits fast paced nuclear divisions in early Drosophila embryo.
Nucleic Acids Res. 48 (16), 9007-9018, 2020.

Jambrovics, K., Uray, I., Keillor, J., Fésüs, L., Balajthy, Z.: Benefits of Combined All-Trans Retinoic Acid and Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia Cells and Further Enhancement by Inhibition of Atypically Expressed Transglutaminase 2.
Cancers (Basel). 12 (3), 648-, 2020.

Batta, G., Hajdu, T., Nagy, P.: Characterization of the Effect of Sphingolipid Accumulation on Membrane Compactness, Dipole Potential, and Mobility of Membrane Components.
In: Lipid Rafts. Methods in Molecular Biology. Ed.: E. Bieberich, Humana, New York, 283-301, 2020, (Methods in Molecular Biology ; 2187) ISBN: 9781071608135

Hajdu, T., Váradi, T., Rebenku, I., Kovács, T., Szöllősi, J., Nagy, P.: Comprehensive Model for Epidermal Growth Factor Receptor Ligand Binding Involving Conformational States of the Extracellular and the Kinase Domains.
Front. Cell. Dev. Biol. 8 1-53, 2020.

Zákány, F., Kovács, T., Panyi, G., Varga, Z.: Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels.
Biochim. Biophys. Acta. Mol. Cell Biol. Lipids. 1865 (8), 1-27, 2020.

Lontay, B., Kiss, A., Virág, L., Tar, K.: How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington's Disease? A Comprehensive Review.
Int. J. Mol. Sci. 21 (12), 1-34, 2020.

Nagyné Szabó, Á., Szendi-Szatmári, T., Szöllősi, J., Nagy, P.: Quo vadis FRET? Förster's method in the era of superresolution.
Methods Appl. Fluoresc. 8 (3), 1-18, 2020.

Kiss, A., Ráduly, A., Regdon, Z., Polgár, Z., Tarapcsák, S., Sturniolo, I., El-Hamoly, T., Virág, L., Hegedűs, C.: Targeting nuclear NAD+ synthesis inhibits DNA repair, impairs metabolic adaptation increases chemosensitivity of U-2OS osteosarcoma cells.
Cancers (Basel). 12 (5), 1-27, 2020.

Douida, A., Batista, F., Robaszkiewicz, A., Botó, P., Aladdin, A., Szenykiv, M., Czinege, R., Virág, L., Tar, K.: The proteasome activator PA200 regulates expression of genes involved in cell survival upon selective mitochondrial inhibition in neuroblastoma cells.
J. Cell. Mol. Med. 24 (12), 6716-6730, 2020.

Kónya, Z., Bécsi, B., Kiss, A., Horváth, D., Hadháziné Raics, M., Kövér, K., Lontay, B., Erdődi, F.: Inhibition of protein phosphatase-1 and -2A by ellagitannins: structure-inhibitory potency relationships and influences on cellular systems.
J. Enzym. Inhib. Med. Chem. 34 (1), 500-509, 2019.

Kovács, P., Csonka, T., Kovács, T., Sári, Z., Ujlaki, G., Sipos, A., Karányi, Z., Szeőcs, D., Hegedűs, C., Uray, K., Jankó, L., Kiss, M., Kiss, B., Laoui, D., Virág, L., Méhes, G., Bai, P., Mikó, E.: Lithocholic acid, a metabolite of the microbiome, increases oxidative stress in breast cancer.
Cancers (Basel). 11 1-31, 2019.

Regdon, Z., Robaszkiewicz, A., Kovács, K., Rygielska, Ż., Hegedűs, C., Bodoor, K., Szabó, É., Virág, L.: LPS protects macrophages from AIF-independent parthanatos by downregulation of PARP1 expression, induction of SOD2 expression, and a metabolic shift to aerobic glycolysis.
Free Radic. Biol. Med. 131 184-196, 2019.

Costea, T., Nagy, P., Ganea, C., Szöllősi, J., Mocanu, M.: Molecular Mechanisms and Bioavailability of Polyphenols in Prostate Cancer.
Int. J. Mol. Sci. 20 (5), 1-39, 2019.

Tokarz, P., Poszaj, T., Regdon, Z., Virág, L., Robaszkiewicz, A.: PARP1-LSD1 functional interplay controls transcription of SOD2 that protects human pro-inflammatory macrophages from death under an oxidative condition.
Free Radic. Biol. Med. 131 218-224, 2019.

Robinson, N., Ganesan, R., Hegedűs, C., Kovács, K., Kufer, T., Virág, L.: Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos.
Redox Biol. 26 1-8, 2019.

Szendi-Szatmári, T., Nagyné Szabó, Á., Szöllősi, J., Nagy, P.: Reducing the Detrimental Effects of Saturation Phenomena in FRET Microscopy.
Anal. Chem. 91 (9), 6378-6382, 2019.

Virág, L., Jaén, R., Regdon, Z., Boscá, L., Prieto, P.: Self-defense of macrophages against oxidative injury: fighting for their own survival.
Redox Biol. 26 1-9, 2019.

Bakondi, E., Singh, S., Hajnády, Z., Nagy-Pénzes, M., Regdon, Z., Kovács, K., Hegedűs, C., Madácsy, T., Maléth, J., Hegyi, P., Demény, M., Nagy, T., Kéki, S., Szabó, É., Virág, L.: Spilanthol Inhibits Inflammatory Transcription Factors and iNOS Expression in Macrophages and Exerts Anti-inflammatory Effects in Dermatitis and Pancreatitis.
Int. J. Mol. Sci. 20 (17), 1-18, 2019.

Jambrovics, K., Uray, I., Keresztessy, Z., Keillor, J., Fésüs, L., Balajthy, Z.: Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-kB activation.
Haematol-Hematol. J. 104 (3), 505-515, 2019.

Batta, G., Soltész, L., Kovács, T., Bozó, T., Mészár, Z., Kellermayer, M., Szöllősi, J., Nagy, P.: Alterations in the properties of the cell membrane due to glycosphingolipid accumulation in a model of Gaucher disease.
Sci Rep. 8 (1), 157, 2018.

Chowdhury, P., Powell, R., Stephan, C., Uray, I., Talley, T., Karki, M., Tripathi, D., Park, Y., Mancini, M., Davies, P., Dere, R.: Bexarotene: a Novel Modulator of AURKA and the Primary Cilium in VHL-deficient Cells.
J. Cell Sci. 131 1-12, 2018.

Barok, M., Puhka, M., Vereb, G., Szöllősi, J., Isola, J., Joensuu, H.: Cancer-derived exosomes from HER2-positive cancer cells carry trastuzumab-emtansine into cancer cells leading to growth inhibition and caspase activation.
BMC Cancer. 18 (1), 504-516, 2018.

Hrubi, E., Imre, L., Robaszkiewicz, A., Virág, L., Kerényi, F., Nagy, K., Varga, G., Jenei, A., Hegedűs, C.: Diverse effect of BMP-2 homodimer on mesenchymal progenitors of different origin.
Hum. Cell. 31 (2), 139-148, 2018.

Tempka, D., Tokarz, P., Chmielewska, K., Kluska, M., Pietrzak, J., Rygielska, Ż., Virág, L., Robaszkiewicz, A.: Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair.
Redox Biol. 15 316-326, 2018.

Filippi, A., Picot, T., Aanei, C., Nagy, P., Szöllősi, J., Campos, L., Ganea, C., Mocanu, M.: Epigallocatechin-3-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines.
Int. J. Food Sci. Nutr. 69 (5), 584-597, 2018.

Robaszkiewicz, A., Wisnik, E., Regdon, Z., Chmielewska, K., Virág, L.: PARP1 facilitates EP300 recruitment to the promoters of the subset of RBL2-dependent genes.
Biochim. Biophys. Acta. Gene Regul. Mech. 1861 (1), 41-53, 2018.

Pietrzak, J., Spickett, C., Płoszaj, T., Virág, L., Robaszkiewicz, A.: PARP1 promoter links cell cycle progression with adaptation to oxidative environment.
Redox Biol. 18 1-5, 2018.

Hegedűs, C., Kovács, K., Polgár, Z., Regdon, Z., Szabó, É., Robaszkiewicz, A., Forman, H., Martner, A., Virág, L.: Redox control of cancer cell destruction.
Redox Biol. 16 59-74, 2018.

Bodnár, E., Bakondi, E., Kovács, K., Hegedűs, C., Lakatos, P., Robaszkiewicz, A., Regdon, Z., Virág, L., Szabó, É.: Redox Profiling Reveals Clear Differences between Molecular Patterns of Wound Fluids from Acute and Chronic Wounds.
Oxid. Med. Cell. Longev. 2018 1-12, 2018.

Csősz, É., Márkus, B., Darula, Z., Medzihradszky-Fölkl, K., Nemes, J., Szabó, E., Tőzsér, J., Kiss, C., Márton, I.: Salivary proteome profiling of oral squamous cell carcinoma in a Hungarian population.
FEBS Open Bio. 8 (4), 556-569, 2018.

Pogácsás, L., Felföldi, N., Bodnár, E., Csordás, A., Szabó, É.: A krónikus vénás elégtelenség klasszifikációja és korszerű kezelése.
Bőrgyógyász. Venerol. Szle. 93 (3), 108-113, 2017.

Mocanu, M., Nagy, P., Szöllősi, J.: Detection of protein interactions by Subcellular Localization Assay.
Cytom. Part A. 91 (7), 657-658, 2017.

Tóth, G., Szöllősi, J., Vereb, G.: Quantitating ADCC against adherent cells: impedance-based detection is superior to release, membrane permeability, or caspase activation assays in resolving antibody dose response.
Cytom. Part A. 91 (10), 1021-1029, 2017.

Kovács, T., Batta, G., Zákány, F., Szöllősi, J., Nagy, P.: The dipole potential correlates with lipid raft markers in the plasma membrane of living cells.
J. Lipid Res. 58 (8), 1681-1691, 2017.

Kovács, T., Batta, G., Hajdu, T., Nagyné Szabó, Á., Váradi, T., Zákány, F., Csomós, I., Szöllősi, J., Nagy, P.: The Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency.
Sci. Rep. 6 35850, 2016.

Szöllősi, J., Vereb, G., Nagy, P.: The flow of events: how the sequence of molecular interactions is seen by the latest, user-friendly high throughput flow cytometric FRET.
Cytom. Part A. 89 (10), 881-885, 2016.