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Publication list
2023
Bokor, É.,
Kecskés, D.,
Gombás, F.,
Fehér, A.,
Kardos, E.,
Dabian, A.,
Vonza, Z.,
Szennyes, E.,
Somsák, L.:
First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines.
New Journal of Chemistry 47 (1), 56-74, 2023.
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
Kacsir, I.,
Sipos, A.,
Kiss, T.,
Major, E.,
Bajusz, N.,
Tóth, E.,
Buglyó, P.,
Somsák, L.,
Kardos, G.,
Bai, P.,
Bokor, É.:
Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria.
Front. Chem. 11 1-18, 2023.
Journal metrics:
Q1 Chemistry (miscellaneous)
Kacsir, I.,
Sipos, A.,
Major, E.,
Bajusz, N.,
Bényei, A.,
Buglyó, P.,
Somsák, L.,
Kardos, G.,
Bai, P.,
Bokor, É.:
Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities.
Molecules. 28 (7), 1-55, 2023.
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
2022
Bokor, É.,
Ferenczi, A.,
Hashimov, M.,
Juhász-Tóth, É.,
Götz, Z.,
Zaki, A.,
Somsák, L.:
First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of.
Molecules. 27 (22), 1-16, 2022.
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
Kacsir, I.,
Sipos, A.,
Bényei, A.,
Janka, E.,
Buglyó, P.,
Somsák, L.,
Bai, P.,
Bokor, É.:
Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models.
Int. J. Mol. Sci. 23 (2), 1-39, 2022.
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
Balázs, B.,
Tóth, Z.,
Kacsir, I.,
Sipos, A.,
Buglyó, P.,
Somsák, L.,
Bokor, É.,
Kardos, G.,
Bai, P.:
Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands.
Front. Chem. 10 1-9, 2022.
Journal metrics:
Q1 Chemistry (miscellaneous)
2021
Sipos, Á.,
Szennyes, E.,
Hajnal, É.,
Kun, S.,
Szabó, E.,
Uray, K.,
Somsák, L.,
Docsa, T.,
Bokor, É.:
Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors.
Pharmaceuticals. 14 (4), 1-27, 2021.
Journal metrics:
Q1 Drug Discovery
Q2 Molecular Medicine
Q1 Pharmaceutical Science
Kacsir, I.,
Sipos, A.,
Ujlaki, G.,
Buglyó, P.,
Somsák, L.,
Bai, P.,
Bokor, É.:
Ruthenium half-sandwich type complexes with bidentate monosaccharide ligands show antineoplastic activity in ovarian cancer cell models through reactive oxygen species production.
Int. J. Mol. Sci. 221 1-41, 2021.
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
2020
Kyriakis, E.,
Karra, A.,
Papaioannou, O.,
Solovou, T.,
Skamnaki, V.,
Liggri, P.,
Zographos, S.,
Szennyes, E.,
Bokor, É.,
Kun, S.,
Psarra, A.,
Somsák, L.,
Leonidas, D.:
The architecture of hydrogen and sulfur α-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Bioorg. Med. Chem. 28 (1), 1-10, 2020.
Journal metrics:
Q3 Biochemistry
Q2 Clinical Biochemistry
Q2 Drug Discovery
Q3 Molecular Biology
Q3 Molecular Medicine
Q2 Organic Chemistry
Q2 Pharmaceutical Science
2019
Barr, D.,
Szennyes, E.,
Bokor, É.,
Al-Oanzi, Z.,
Moffatt, C.,
Kun, S.,
Docsa, T.,
Sipos, Á.,
Davies, M.,
Mathomes, R.,
Snape, T.,
Agius, L.,
Somsák, L.,
Hayes, J.:
Identification of C-[béta]-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: in Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies.
ACS Chem. Biol. 14 (7), 1460-1470, 2019.
Journal metrics:
Q1 Biochemistry
D1 Medicine (miscellaneous)
Q1 Molecular Medicine
Somsák, L.,
Bokor, É.,
Juhász, L.,
Kun, S.,
Lázár, L.,
Juhász-Tóth, É.,
Tóth, M.:
New syntheses towards C-glycosyl type glycomimetics.
Pure Appl. Chem. 91 (7), 1159-1175, 2019.
Journal metrics:
Q2 Chemical Engineering (miscellaneous)
Q2 Chemistry (miscellaneous)
Szennyes, E.,
Bokor, É.,
Docsa, T.,
Sipos, Á.,
Somsák, L.:
Synthesis of C-β-D-glucopyranosyl derivatives of some fused azoles for the inhibition of glycogen phosphorylase.
Carbohydr. Res. 472 33-41, 2019.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2018
Kun, S.,
Begum, J.,
Kyriakis, E.,
Stamati, E.,
Barkas, T.,
Szennyes, E.,
Bokor, É.,
Szabó, E.,
Stravodimos, G.,
Sipos, Á.,
Docsa, T.,
Gergely, P.,
Moffatt, C.,
Patraskaki, M.,
Kokolaki, M.,
Gkerdi, A.,
Skamnaki, V.,
Leonidas, D.,
Somsák, L.,
Hayes, J.:
A multidisciplinary study of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
Eur. J. Med. Chem. 147 266-278, 2018.
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
Nagy, L.,
Márton, J.,
Vida, A.,
Kis, G.,
Bokor, É.,
Kun, S.,
Gönczi, M.,
Docsa, T.,
Tóth, A.,
Antal, M.,
Gergely, P.,
Csóka, B.,
Pacher, P.,
Somsák, L.,
Bai, P.:
Glycogen phosphorylase inhibition improves beta cell function.
Br. J. Pharmacol. 175 (2), 301-319, 2018.
Kyriakis, E.,
Solovou, T.,
Kun, S.,
Czifrák, K.,
Szőcs, B.,
Juhász, L.,
Bokor, É.,
Stravodimos, G.,
Kantsadi, A.,
Chatzileontiadou, D.,
Skamnaki, V.,
Somsák, L.,
Leonidas, D.:
Probing the [beta]-pocket of the active site of human liver glycogen phosphorylase with 3-(C-[beta]-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorganic Chem. 77 485-493, 2018.
Journal metrics:
Q3 Biochemistry
Q2 Drug Discovery
Q3 Molecular Biology
Q2 Organic Chemistry
Kun, S.,
Bokor, É.,
Sipos, Á.,
Docsa, T.,
Somsák, L.:
Synthesis of New C- and N-beta-D-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase.
Molecules. 23 (3), 1-17, 2018.
Journal metrics:
Q2 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
Szennyes, E.,
Bokor, É.,
Langer, P.,
Gyémánt, G.,
Docsa, T.,
Sipos, Á.,
Somsák, L.:
The first general synthesis of 2-C-(beta-D-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes.
New J. Chem. 42 (21), 17439-17446, 2018.
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q1 Materials Chemistry
2017
Bokor, É.,
Kun, S.,
Goyard, D.,
Tóth, M.,
Praly, J.,
Vidal, S.,
Somsák, L.:
C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential.
Chem. Rev. 117 (3), 1687-1764, 2017.
Journal metrics:
D1 Chemistry (miscellaneous)
Bokor, É.,
Kyriakis, E.,
Solovou, T.,
Koppány, C.,
Kantsadi, A.,
Szabó, E.,
Szakács, A.,
Stravodimos, G.,
Docsa, T.,
Skamnaki, V.,
Zographos, S.,
Gergely, P.,
Leonidas, D.,
Somsák, L.:
Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J. Med. Chem. 60 (22), 9251-9262, 2017.
Journal metrics:
D1 Drug Discovery
Q1 Molecular Medicine
Szennyes, E.,
Bokor, É.,
Kiss-Szikszai, A.,
Somsák, L.,
Pascal, Y.:
Preparation of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-D-glycero-D-gulo-heptonimidamide.
In: Carbohydrate Chemistry: Proven Synthetic Methods / Christian Vogel, Paul Murphy, CRC Press-Taylor & Francis Group, Boca Raton, 323-332, 2017, (Volume 4 ) ISBN: 9781498726917
Agócs, A.,
Bokor, É.,
Takátsy, A.,
Lóránd, T.,
Deli, J.,
Somsák, L.,
Nagy, V.:
Synthesis of carotenoid-monosaccharide conjugates via azide-alkyne click-reaction.
Tetrahedron. 73 (5), 519-526, 2017.
Journal metrics:
Q2 Biochemistry
Q2 Drug Discovery
Q2 Organic Chemistry
Kantsadi, A.,
Stravodimos, G.,
Kyriakis, E.,
Chatzileontiadou, D.,
Solovou, T.,
Kun, S.,
Bokor, É.,
Somsák, L.:
van der Waals interactions govern C-[beta]-D-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol. 199 (1), 57-67, 2017.
2016
Bokor, É.,
Széles, Z.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
C-Glucopyranosyl-1,2,4-triazol-5-ones: synthesis and inhibition of glycogen phosphorylase.
Carbohydr. Res. 429 128-134, 2016.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2023
Bokor, É.,
Kecskés, D.,
Gombás, F.,
Fehér, A.,
Kardos, E.,
Dabian, A.,
Vonza, Z.,
Szennyes, E.,
Somsák, L.:
First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines.
New Journal of Chemistry 47 (1), 56-74, 2023.
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
Kacsir, I.,
Sipos, A.,
Kiss, T.,
Major, E.,
Bajusz, N.,
Tóth, E.,
Buglyó, P.,
Somsák, L.,
Kardos, G.,
Bai, P.,
Bokor, É.:
Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria.
Front. Chem. 11 1-18, 2023.
Journal metrics:
Q1 Chemistry (miscellaneous)
Kacsir, I.,
Sipos, A.,
Major, E.,
Bajusz, N.,
Bényei, A.,
Buglyó, P.,
Somsák, L.,
Kardos, G.,
Bai, P.,
Bokor, É.:
Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities.
Molecules. 28 (7), 1-55, 2023.
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
2022
Bokor, É.,
Ferenczi, A.,
Hashimov, M.,
Juhász-Tóth, É.,
Götz, Z.,
Zaki, A.,
Somsák, L.:
First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of.
Molecules. 27 (22), 1-16, 2022.
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
Kacsir, I.,
Sipos, A.,
Bényei, A.,
Janka, E.,
Buglyó, P.,
Somsák, L.,
Bai, P.,
Bokor, É.:
Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models.
Int. J. Mol. Sci. 23 (2), 1-39, 2022.
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
Balázs, B.,
Tóth, Z.,
Kacsir, I.,
Sipos, A.,
Buglyó, P.,
Somsák, L.,
Bokor, É.,
Kardos, G.,
Bai, P.:
Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands.
Front. Chem. 10 1-9, 2022.
Journal metrics:
Q1 Chemistry (miscellaneous)
2021
Sipos, Á.,
Szennyes, E.,
Hajnal, É.,
Kun, S.,
Szabó, E.,
Uray, K.,
Somsák, L.,
Docsa, T.,
Bokor, É.:
Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors.
Pharmaceuticals. 14 (4), 1-27, 2021.
Journal metrics:
Q1 Drug Discovery
Q2 Molecular Medicine
Q1 Pharmaceutical Science
Kacsir, I.,
Sipos, A.,
Ujlaki, G.,
Buglyó, P.,
Somsák, L.,
Bai, P.,
Bokor, É.:
Ruthenium half-sandwich type complexes with bidentate monosaccharide ligands show antineoplastic activity in ovarian cancer cell models through reactive oxygen species production.
Int. J. Mol. Sci. 221 1-41, 2021.
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
2020
Kyriakis, E.,
Karra, A.,
Papaioannou, O.,
Solovou, T.,
Skamnaki, V.,
Liggri, P.,
Zographos, S.,
Szennyes, E.,
Bokor, É.,
Kun, S.,
Psarra, A.,
Somsák, L.,
Leonidas, D.:
The architecture of hydrogen and sulfur α-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Bioorg. Med. Chem. 28 (1), 1-10, 2020.
Journal metrics:
Q3 Biochemistry
Q2 Clinical Biochemistry
Q2 Drug Discovery
Q3 Molecular Biology
Q3 Molecular Medicine
Q2 Organic Chemistry
Q2 Pharmaceutical Science
2019
Barr, D.,
Szennyes, E.,
Bokor, É.,
Al-Oanzi, Z.,
Moffatt, C.,
Kun, S.,
Docsa, T.,
Sipos, Á.,
Davies, M.,
Mathomes, R.,
Snape, T.,
Agius, L.,
Somsák, L.,
Hayes, J.:
Identification of C-[béta]-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: in Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies.
ACS Chem. Biol. 14 (7), 1460-1470, 2019.
Journal metrics:
Q1 Biochemistry
D1 Medicine (miscellaneous)
Q1 Molecular Medicine
Somsák, L.,
Bokor, É.,
Juhász, L.,
Kun, S.,
Lázár, L.,
Juhász-Tóth, É.,
Tóth, M.:
New syntheses towards C-glycosyl type glycomimetics.
Pure Appl. Chem. 91 (7), 1159-1175, 2019.
Journal metrics:
Q2 Chemical Engineering (miscellaneous)
Q2 Chemistry (miscellaneous)
Szennyes, E.,
Bokor, É.,
Docsa, T.,
Sipos, Á.,
Somsák, L.:
Synthesis of C-β-D-glucopyranosyl derivatives of some fused azoles for the inhibition of glycogen phosphorylase.
Carbohydr. Res. 472 33-41, 2019.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2018
Kun, S.,
Begum, J.,
Kyriakis, E.,
Stamati, E.,
Barkas, T.,
Szennyes, E.,
Bokor, É.,
Szabó, E.,
Stravodimos, G.,
Sipos, Á.,
Docsa, T.,
Gergely, P.,
Moffatt, C.,
Patraskaki, M.,
Kokolaki, M.,
Gkerdi, A.,
Skamnaki, V.,
Leonidas, D.,
Somsák, L.,
Hayes, J.:
A multidisciplinary study of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
Eur. J. Med. Chem. 147 266-278, 2018.
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
Nagy, L.,
Márton, J.,
Vida, A.,
Kis, G.,
Bokor, É.,
Kun, S.,
Gönczi, M.,
Docsa, T.,
Tóth, A.,
Antal, M.,
Gergely, P.,
Csóka, B.,
Pacher, P.,
Somsák, L.,
Bai, P.:
Glycogen phosphorylase inhibition improves beta cell function.
Br. J. Pharmacol. 175 (2), 301-319, 2018.
Kyriakis, E.,
Solovou, T.,
Kun, S.,
Czifrák, K.,
Szőcs, B.,
Juhász, L.,
Bokor, É.,
Stravodimos, G.,
Kantsadi, A.,
Chatzileontiadou, D.,
Skamnaki, V.,
Somsák, L.,
Leonidas, D.:
Probing the [beta]-pocket of the active site of human liver glycogen phosphorylase with 3-(C-[beta]-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorganic Chem. 77 485-493, 2018.
Journal metrics:
Q3 Biochemistry
Q2 Drug Discovery
Q3 Molecular Biology
Q2 Organic Chemistry
Kun, S.,
Bokor, É.,
Sipos, Á.,
Docsa, T.,
Somsák, L.:
Synthesis of New C- and N-beta-D-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase.
Molecules. 23 (3), 1-17, 2018.
Journal metrics:
Q2 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
Szennyes, E.,
Bokor, É.,
Langer, P.,
Gyémánt, G.,
Docsa, T.,
Sipos, Á.,
Somsák, L.:
The first general synthesis of 2-C-(beta-D-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes.
New J. Chem. 42 (21), 17439-17446, 2018.
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q1 Materials Chemistry
2017
Bokor, É.,
Kun, S.,
Goyard, D.,
Tóth, M.,
Praly, J.,
Vidal, S.,
Somsák, L.:
C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential.
Chem. Rev. 117 (3), 1687-1764, 2017.
Journal metrics:
D1 Chemistry (miscellaneous)
Bokor, É.,
Kyriakis, E.,
Solovou, T.,
Koppány, C.,
Kantsadi, A.,
Szabó, E.,
Szakács, A.,
Stravodimos, G.,
Docsa, T.,
Skamnaki, V.,
Zographos, S.,
Gergely, P.,
Leonidas, D.,
Somsák, L.:
Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J. Med. Chem. 60 (22), 9251-9262, 2017.
Journal metrics:
D1 Drug Discovery
Q1 Molecular Medicine
Szennyes, E.,
Bokor, É.,
Kiss-Szikszai, A.,
Somsák, L.,
Pascal, Y.:
Preparation of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-D-glycero-D-gulo-heptonimidamide.
In: Carbohydrate Chemistry: Proven Synthetic Methods / Christian Vogel, Paul Murphy, CRC Press-Taylor & Francis Group, Boca Raton, 323-332, 2017, (Volume 4 ) ISBN: 9781498726917
Agócs, A.,
Bokor, É.,
Takátsy, A.,
Lóránd, T.,
Deli, J.,
Somsák, L.,
Nagy, V.:
Synthesis of carotenoid-monosaccharide conjugates via azide-alkyne click-reaction.
Tetrahedron. 73 (5), 519-526, 2017.
Journal metrics:
Q2 Biochemistry
Q2 Drug Discovery
Q2 Organic Chemistry
Kantsadi, A.,
Stravodimos, G.,
Kyriakis, E.,
Chatzileontiadou, D.,
Solovou, T.,
Kun, S.,
Bokor, É.,
Somsák, L.:
van der Waals interactions govern C-[beta]-D-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol. 199 (1), 57-67, 2017.
2016
Bokor, É.,
Széles, Z.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
C-Glucopyranosyl-1,2,4-triazol-5-ones: synthesis and inhibition of glycogen phosphorylase.
Carbohydr. Res. 429 128-134, 2016.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
Szennyes, E.,
Bokor, É.,
Batta, G.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
Improved preparation of 4(5)-aryl-2-(β-D-glucopyranosyl)-imidazoles, the most efficient glucose analogue inhibitors of glycogen phosphorylase.
RSC Adv. 6 (97), 94787-94794, 2016.
Journal metrics:
Q1 Chemical Engineering (miscellaneous)
Q1 Chemistry (miscellaneous)
Kantsadi, A.,
Bokor, É.,
Kun, S.,
Stravodimos, G.,
Chatzileontiadou, D.,
Leonidas, D.,
Juhász-Tóth, É.,
Szakács, A.,
Batta, G.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
Synthetic, enzyme kinetic, and protein crystallographic studies of C-[béta]-D-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur. J. Med. Chem. 123 737-745, 2016.
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
2015
Bokor, É.,
Kun, S.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
4(5)-Aryl-2-C-glucopyranosyl-imidazoles as New Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase.
ACS Med. Chem. Lett. 6 1215-1219, 2015.
Journal metrics:
Q2 Biochemistry
Q1 Drug Discovery
Q1 Organic Chemistry
Bokor, É.,
Szennyes, E.,
Csupász, T.,
Tóth, N.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
C-(2-Deoxy-D-arabino-hex-1-enopyranosyl)-oxadiazoles: synthesis of possible isomers and their evaluation as glycogen phosphorylase inhibitors.
Carbohydr. Res. 412 71-79, 2015.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
Misra, A.,
Bokor, É.,
Kun, S.,
Bolyog-Nagy, E.,
Kathó, Á.,
Joó, F.,
Somsák, L.:
Chemoselective hydration of glycosyl cyanides to C-glycosyl formamides using ruthenium complexes in aqueous media.
Tetrahedron Lett. 56 (44), 5995-5998, 2015.
Journal metrics:
Q3 Biochemistry
Q2 Drug Discovery
Q2 Organic Chemistry
Szőcs, B.,
Bokor, É.,
Szabó, E.,
Kiss-Szikszai, A.,
Tóth, M.,
Somsák, L.:
Synthesis of 5-aryl-3-C-glycosyl- and unsymmetrical 3,5-diaryl-1,2,4-triazoles from alkylidene-amidrazones.
RSC Advances. 5 (54), 43620-43629, 2015.
Journal metrics:
Q1 Chemical Engineering (miscellaneous)
Q1 Chemistry (miscellaneous)
2014
Kun, S.,
Bokor, É.,
Varga, G.,
Szőcs, B.,
Páhi, A.,
Czifrák, K.,
Tóth, M.,
Juhász, L.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4- triazoles, nanomolar inhibitors of glycogen phosphorylase.
Eur. J. Med. Chem. 76 567-579, 2014.
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
Somsák, L.,
Bokor, É.,
Czibere, B.,
Czifrák, K.,
Koppány, C.,
Kulcsár, L.,
Kun, S.,
Szilágyi, E.,
Tóth, M.,
Docsa, T.,
Gergely, P.:
Synthesis of C-xylopyranosyl- and xylopyranosylidene-spiro-heterocycles as potential inhibitors of glycogen phosphorylase.
Carbohydr. Res. 399 38-48, 2014.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2013
Bokor, É.,
Fekete, A.,
Varga, G.,
Szőcs, B.,
Czifrák, K.,
Komáromi, I.,
Somsák, L.:
C-(β-d-Glucopyranosyl)formamidrazones, formic acid hydrazides and their transformations into 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazoles: a synthetic and computational study.
Tetrahedron. 69 (48), 10391-10404, 2013.
Journal metrics:
Q2 Biochemistry
Q1 Drug Discovery
Q1 Organic Chemistry
Bokor, É.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.
ACS Med. Chem. Lett. 4 (7), 612-615, 2013.
Journal metrics:
Q1 Biochemistry
Q1 Drug Discovery
Q1 Organic Chemistry
Bokor, É.,
Szilágyi, E.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
Synthesis of substituted 2-(β-d-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase.
Carbohydr. Res. 381C 179-186, 2013.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2012
Bokor, É.,
Koppány, C.,
Gonda, Z.,
Novák, Z.,
Somsák, L.:
Evaluation of bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) as catalyst for the synthesis of 1-glycopyranosyl-4-substituted-1,2,3-triazoles.
Carbohydr. Res. 351 42-48, 2012.
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q2 Medicine (miscellaneous)
Q2 Organic Chemistry
2011
Somsák, L.,
Bokor, É.,
Czifrák, K.,
Juhász, L.,
Tóth, M.:
Carbohydrate Derivatives and Glycomimetic Compounds in Established and Investigational Therapies of Type 2 Diabetes Mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes. Ed.: Marc B. Zimering, InTech Open Access Publisher, Rijeka, 103-126, 2011.
Somsák, L.,
Bokor, É.,
Czifrák, K.,
Juhász, L.,
Tóth, M.:
Carbohydrate derivatives and glycomimetic compounds in established and investigational therapies of type 2 diabetes mellitus.
In: Topics in the Prevention, Treatment and Complications of Type 2 Diabetes / Mark B. Zimering, InTech, Rijeka, 103-126, 2011. ISBN: 9789533075907
2010
Somsák, L.,
Bokor, É.,
Czifrák, K.,
Kónya, B.,
Kun, S.,
Tóth, M.:
A glikogén foszforiláz glükózanalóg gátlószerei, mint potenciális antidiabetikumok.
Magy. Kém. F. 116 (1), 19-30, 2010.
Bokor, É.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
Synthesis of 1-(D-glucopyranosyl)-1,2,3-triazoles and their evaluation as glycogen phosphorylase inhibitors.
Bioorg. Med. Chem. 18 (3), 1171-1180, 2010.
Journal metrics:
Q2 Biochemistry
Q1 Clinical Biochemistry
Q1 Drug Discovery
Q3 Molecular Biology
Q2 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Cheng, K.,
Liu, J.,
Sun, H.,
Bokor, É.,
Czifrák, K.,
Kónya, B.,
Tóth, M.,
Docsa, T.,
Gergely, P.,
Somsák, L.:
Tethered derivatives of D-glucose and pentacyclic triterpenes for homo/heterobivalent inhibition of glycogen phosphorylase.
New J. Chem. 34 1450-1464, 2010.
Journal metrics:
Q2 Catalysis
Q1 Chemistry (miscellaneous)
Q1 Materials Chemistry
2009
Chrysina, E.,
Bokor, É.,
Alexacou, K.,
Charavgi, M.,
Oikonomakos, G.,
Zographos, S.,
Leonidas, D.,
Oikonomakos, N.,
Somsák, L.:
Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case.
Tetrahedron Asymmetry. 20 (6-8), 733-740, 2009.
Journal metrics:
Q2 Catalysis
Q1 Inorganic Chemistry
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
Tóth, M.,
Kun, S.,
Bokor, É.,
Benltifa, M.,
Tallec, G.,
Vidal, S.,
Docsa, T.,
Gergely, P.,
Somsák, L.,
Praly, J.:
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.
Bioorg. Med. Chem. 17 (13), 4773-4785, 2009.
Journal metrics:
Q2 Biochemistry
Q1 Clinical Biochemistry
Q1 Drug Discovery
Q3 Molecular Biology
Q2 Molecular Medicine
Q1 Organic Chemistry
Q1 Pharmaceutical Science
2008
Somsák, L.,
Hüse, C.,
Felföldi, N.,
Kónya, B.,
Kútvölgyi, K.,
Bokor, É.,
Czifrák, K.:
Assessment of synthetic methods for the preparation of N-beta-D-glucopyranosyl-N'-substituted ureas, -thioureas and related compounds.
Carbohydr. Res. 343 (12), 2083-2093, 2008.
Journal metrics:
Q2 Analytical Chemistry
Q2 Biochemistry
Q1 Medicine (miscellaneous)
Q2 Organic Chemistry
Somsák, L.,
Czifrák, K.,
Tóth, M.,
Bokor, É.,
Chrysina, E.,
Alexacou, K.,
Hayes, J.,
Tiraidis, C.,
Lazoura, E.,
Leonidas, D.,
Zographos, S.,
Oikonomakos, G.:
New inhibitors of glycogen phosphorylase as potential antidiabetic agents.
Curr. Med. Chem. 15 (28), 2933-2983, 2008.
Journal metrics:
Q1 Molecular Medicine
D1 Pharmacology
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updated: 2024-12-19, 02:05